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Plant extracts×HIGUCHI INC. - List of Manufacturers, Suppliers, Companies and Products

Plant extracts Product List

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Cosmetic ingredients Miracle revival plant extract moisturizing anti-stress jelly essence

Miraculous resurrection plant, moisturizing, anti-stress, Tamerisk cypress, resurrection grass, osmoregulatory function, cell protection, trehalose, dehydrin.

Jelisin is an extract from a drought-resistant plant called Temarikatabiba (Selaginella lepidophylla), which is native to the Chihuahuan Desert in Texas, USA. Temarikatabiba possesses excellent active components and characteristics that allow it to adapt to the extreme environment of the desert, which has low nutrients and extreme dryness. <Features> The dried leaves fold into a spherical shape, reducing the surface area from which moisture can evaporate. <Active Components> It contains trehalose and dehydrins, which help control the osmotic pressure of cells, allowing them to be maintained even in extreme dryness. Additionally, trehalose serves as an energy source, supporting cellular activity. <Efficacy> Moisturizing and stress-relieving effects.

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Body care ingredient African traditional breast enhancement plant extract Kigerin

Bust up, African tradition, bust lift up, sausage tree, France No.1, saponin, flavonoid, firmness improvement, elasticity improvement.

KIGELINE(R)/Kigerin is an extract from the fruit of Kigelia africana (sausage tree), used as a traditional African breast enhancement agent. This product is the best-selling item from Green Tech in France. <Main Ingredients> Saponins, Phytosterols, Flavonoids <Mechanism of Action> Saponins and phytosterols act on dermal fibroblasts, promoting the synthesis of hyaluronic acid and collagen. The increase in these extracellular matrix components contributes to improving skin firmness and elasticity, as well as increasing skin moisture retention, thereby enhancing the firmness and fullness of the breasts. Flavonoids exhibit anti-aging effects by promoting blood circulation. The additive effects of these three components provide firmness and elasticity to the breasts, resulting in a lift. <Efficacy> Breast enhancement effect: Lifts the breasts by improving skin elasticity and moisture retention. Anti-aging effect: Beautifies the neck line through improved firmness. <In Vivo> Accuracy measurement by iconography - Breast enhancement: +70% - Lift: +18%

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Cosmetic ingredients for eye area care with glycation inhibition, highland plant extract, Miralis.

Alpine plants, gentian, glycation inhibition, eye bags, eyelid sagging prevention, eye care, organic, extracellular matrix reinforcement, antioxidant, anti-inflammatory.

The eyes are said to be the most important part of interpersonal communication. During the COVID-19 pandemic, the market for eye care products has expanded as wearing masks has become the norm. Miralis is an extract obtained from the roots of the gentian, a high-altitude plant, harvested using sustainable methods, and standardized for its active ingredient, gentiopicroside. <Mechanism of Action> It suppresses six aging-promoting pathways and cares for the eyelids (upper part of the eye), tear troughs, under-eye bags, and dark circles. - Glycation suppression - Extracellular matrix aging suppression - Antioxidant - Anti-inflammatory - Lymphatic drainage promotion - Angiogenesis suppression <In Vitro> - NRF2: +21% - VEGF-A: -15% - Collagen 1 synthesis promotion: +76% - Glycation suppression Activation of glyoxalase 1: +35% Suppression of AGE (carboxymethyllysine) production: -111% - UV protection: Elastin protection: +41% <In Vivo> - Eyelid wrinkle depth: -22% - Tear trough depth: -14% - Under-eye bag swelling: -18% - Dark circle color: -14%

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Cosmetic ingredient Active plankton extract Silidine

Plankton extract rich in active ingredients, cultivated under excessive oxidative stress. Stimulates endothelin-1 and improves erythema and swelling in the legs.

SILIDINE is a plankton extract made from microalgae rich in nutrients, cultivated under excessive oxidative stress. By cultivating it under sunlight, the excessive oxidative stress causes changes in the cellular phenotype, resulting in a high concentration of low molecular weight oligosaccharides and the bioaccumulation of trace elements from the culture medium in the microalgae extract. <Mechanism of Action> - It induces the expression of the endothelin-1 gene. The endothelin-1 gene stimulates the contraction of veins and improves blood retention. It helps improve acne and erythema caused by swelling and inflammation. When applied to the feet, SILIDINE alleviates heaviness and fatigue in the legs. <Efficacy> Reduction of facial redness: 19% improvement (improvement confirmed in 86% of subjects) Reduction of leg swelling: 36% improvement Immediate effects: moisturizing, refreshing sensation, etc.

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Cosmetic ingredient: Cetylin, an anti-wrinkle ingredient that inhibits glycation from Colohar seed extract.

Restoration of barrier function and anti-wrinkle effect through the anti-glycation and keratinocyte differentiation-promoting effects of Korohas seed extract. Active ingredient: Galactomannan oligosaccharides.

SETILINE is an extract from fenugreek (koroha) seeds. It contains galactomannan oligosaccharides as its main component, standardized to contain 80% or more of mannose and galactose. Galactomannan oligosaccharides are said to have effects such as suppressing glycation reactions, promoting keratinocyte differentiation, and exhibiting antioxidant properties. This raw material is an extract of koroha seeds that possesses various effects attributed to galactomannan oligosaccharides. <DNA Transcriptome Analysis> - Suppression of ISM1 and HK3 gene expression - Promotion of SOD2 gene expression - Stimulation of SAA1 gene expression - Promotion of hyaluronic acid production - Suppression of MAL gene expression - Suppression of KRT16 gene expression and more. <In Vitro> - Suppression of glycation substance production: -26% - Promotion of keratinocyte differentiation - Epidermal densification: +14% <In Vivo> Improvement in elasticity: +45% (maximum: +214%) Improvement in firmness: +11% (maximum: +93%) Anti-wrinkle: maximum: -37% Smoothing: -30.5% and more.

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Cosmetic ingredients for dry and dehydrated skin, microbiome adjustment, holobiosis.

An extract fermented with cold-resistant bacteria from the roots of gentian collected in the French Alps, designed for dry and dehydrated skin with microbiome-regulating ingredients.

This product is an extract fermented with rare cold-resistant bacteria that inhabit the air in France, using the roots of wild gentian organically grown in the high mountains of France. This bacteria is resistant to cold and dry environments, and the holobiosis fermented with it demonstrates effectiveness for dehydrated (water-deficient) and dry (lipid-deficient) skin, showing various efficacy data such as promoting hyaluronic acid synthesis in the epidermis and dermis, antioxidant effects, strengthening barrier functions, and promoting beneficial skin bacteria. Main components: polar lipids, amino acids, loganin acid, swertia amarin. Standardized. In Vitro: Hyaluronic acid synthesis: +62% (keratinocytes), +32% (fibroblasts) CD44 synthesis: +42% (keratinocytes) Lipid synthesis: +147% (keratinocytes) Increase in tight junction-related proteins Increase in basement membrane structural proteins (2 types) Increase in collagen-binding proteins (2 types) Increased expression of antioxidant-related genes (8 types) In Vivo: Skin surface moisture content: +7.3% (all subjects), +12.5% (seborrheic deficiency) Promotion of sebum production: +27% (all), +43% (deficiency) Wrinkle length: -5% Epidermal Staphylococcus: +39% Ralstonia species: +45%

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[New Product] Cosmetic Ingredient: Longevity Gene Stimulator, Plant Extract for Improved Skin Lifespan

Time Ris influences longevity genes, achieving improved skin lifespan [Scheduled to exhibit at the Tokyo 2025/Okinawa 2024 Cosmetics Development Expo (Booth: C11-20)]

It is an extract of the natural ruby-colored Chosen Gomi, a symbol of beauty and longevity, with a wide range of health benefits. It works on the skin longevity mechanism, leading to vibrant, radiant, and smooth skin. <Active Ingredients> Lignans: ≥10%/DM Longevity extension mechanism Schisandrin: 6-8%/DM Autophagy induction & improvement of skin health lifespan Organic Acids: Citric Acid: 10-15% Malic Acid: 10-15% Tartaric Acid ≥2% Cellular energy production <Efficacy> Unit: % Vitro SIRT6: +181 FOXO3: +104 Anti-inflammatory (NfkB: -14, IL6: -66, PGE2: -87) Antioxidant (ROS: -16, SOD2: +50, Catalase: +104) Mitochondrial activity: +55 Autophagy (LAMP2A: +80, LC3A: +44) Skin barrier (Cornifin A, Occludin: +32, Filaggrin: +160, MDA: -22, Epidermal thickness: +63) Dermis (Elastin: +16, MMP1: -72) Vivo TEWL: -24 Moisture content: +34 Microcirculation: +33 Radiance: +47

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