水戸工業 Product Lineup

"I-DOT One" is a high-speed micro dispensing device capable of nano-level precise dispensing through high-speed air pressure control. It can automatically dispense 96 types of reagents into any well with automatic control, completing dispensing in under 20 seconds for 384 wells and under 80 seconds for 1536 wells. (When dispensing 100 nL per reagent) *Currently, we are accepting sample tests for "I-DOT One." A detailed "technical document" explaining the product is also available! (You can view it from "Download") [Features] ■ Achieves ultra-high precision through air pressure method ■ Capable of dispensing cells with high survival rates (≧95%) ■ Dispensing range from 8.0 nL to 80 μL ■ Compact size ■ Reduced contamination risk through non-contact method ■ Compatible with micro well plates of 1536 or more ■ High operability using a touch panel

The German company Dispendix's high-speed micro dispensing device "I-DOT One" is a nano-level dispensing system controlled by high-speed pneumatic control. It can automatically dispense 96 types of reagents into any well under automatic control, capable of dispensing in 20 seconds for 384 wells and within 80 seconds for 1536 wells. 【Features】 ■ Achieves ultra-high precision through pneumatic method! ■ Enables cell dispensing with high survival rates (> 95%)! ■ Dispenses over a wide range from 8 nL to 80 μL! ■ Compact size allows installation in isolators and other spaces! ■ Reduces contamination risk through non-contact method! ■ Compatible with micro well plates of 1536 wells or more! ■ High operability using a touch panel! *For more details, please refer to the catalog or feel free to contact us.

It can dispense single cells with a probability of over 90%. Dispensing into 96 MWP takes about 3 to 5 minutes and can accommodate a wide variety of cell types. Since it uses disposable cartridges, there is no risk of contamination, and no cleaning is required. The minimum sample volume needed is just 5 μL, so rare samples such as clinical samples are not wasted.

We would like to introduce our high-speed micro-dispenser "I-DOT" and the single-cell dispenser "x. sight." <High-speed Micro-dispenser "I-DOT One" *Sample Testing Available> It can dispense a wide range from 8nL to 80μL with an accuracy error of less than 5%. It can automatically dispense 96 types of reagents into any well under automatic control. ■ Achieves very low damage to various cells during dispensing ■ Dispensing is completed within 80 seconds for 1536 wells (when dispensing 100nL per reagent) ■ Reduces contamination risk with a non-contact method <Single-cell Dispenser "x. sight"> Enables single-cell isolation of various cells with high probability and high survival rate. Dispensing into 96 wells is completed in about 3 to 5 minutes. ■ Uses disposable cartridges that have low contamination risk and require no cleaning ■ Supports a minimum of 5μL micro-samples, making it suitable for dispensing rare samples ■ Also available are models compatible with fluorescent imaging and high-magnification imaging *In addition to the product catalog, we are currently offering application materials for "I-DOT One." If you wish to conduct a sample test, please feel free to contact us.

The "I-DOT One" is a dispensing device that achieves high-speed quantitative dispensing at the nano level. By using the "DMA Plate," which has hydrophobic and hydrophilic micro-patterns, it enables high-throughput screening while reducing the amount of cells used. Currently, we are distributing case studies utilizing the "I-DOT One" and "DMA Plate"! You can view them immediately by clicking the download button. [Overview of Case Studies] ■ "High-throughput from spheroid creation to drug screening" Spheroids are formed with one droplet per spheroid using the hanging drop method. High throughput is achieved through analysis on the DMA Plate. ■ "Achieving organic synthesis, mass analysis, and cell-based evaluation quickly and cost-effectively" Suitable for organic solvents (chemical synthesis) and aqueous solutions (biological screening). On-chip organic synthesis, property evaluation, and screening are realized. *Introduction materials for the "I-DOT One" and "DMA Plate" are also available for download.

The high-speed micro dispensing device "I.DOT series" achieves non-contact dispensing, enabling high-speed and high-precision processing. Two new models, 'I.DOT L' and 'I.DOT HT', have been added. 'I.DOT L' (large volume type) has increased the well size from 80μL to 500μL, while 'I.DOT HT' (high throughput type) has increased the maximum number of reagents from 96 to 384. 【Product Features】 ■ Suppresses contamination ■ Contributes to saving experimental time ■ Compatible with SBS standard well plates as well as plates with unique pitches ■ Supports various liquids such as aqueous solvents, buffers, DMSO, glycerol, etc. ■ Allows for reagent savings *For more details, please refer to the catalog. Feel free to contact us with any inquiries.

The new product "I.DOT LT" is a compact non-contact nanoliter dispensing device that supports precise and high-speed dispensing from a minimum of 17.3 nL (H2O) and can handle up to 12 different liquids simultaneously. Equipped with the manufacturer's proprietary high-performance droplet sensor, it reliably confirms the success of the dispensing process. It boasts high-speed performance, dispensing a 384-well plate in 70 seconds (20 nL, H2O). Additionally, its design minimizes dead volume to less than 1 μL (H2O), contributing to the reduction of rare samples and expensive reagents used in NGS and crystallization analysis. 【Features】 ■ Capable of dispensing 12 different liquids at once ■ Minimum dispensing volume of 17.3 nL (H2O) ■ Compact tabletop size (W354×H349×D367mm, 15kg) ■ Capable of dispensing small volumes of aqueous solutions, PCR master mixes, and viscous reagents (glycerol 43%) ■ Achieves high efficiency and high reproducibility in micro-dispensing ■ Can dispense in an array format on slide glass and agar media ★ Currently accepting requests for free demonstrations. Please feel free to contact us if you are interested. *For more details about the product, please refer to the documentation. Don't hesitate to reach out with any inquiries!

**25th Annual Meeting of the Japanese Society for Regenerative Medicine Co-hosted Academic Seminar** ■Chair: Norio Suzuki (Tohoku University) ■"Expanding Spheroid and Organoid Research with Hypoxia × Rotating Suspension Culture" Yoshinobu Utagawa (Tohoku University) ■"The Potential of Hypoxic Culture Indicated by New Cell Behaviors" Masanobu Horie (Kyoto University) ■March 20 (Friday) 12:00 - 12:50 (at Kobe International Conference Center) **Product Overview** 'ClinoStar2' achieves an extremely low-stress culture environment through a rotating suspension method, and with the Hypoxia option, it enables better reproduction of in vivo conditions! It is a very compact device most suitable for the production of organoids and spheroids as an alternative to animal experiments and for rapid culture. Equipped with six independent cameras corresponding to each reactor, it allows for remote observation and adjustment of rotation speed from a tablet. A beautiful, compact all-in-one culture device with incubator functionality! It reduces the frequency of medium changes, helping to conserve research resources. *Please inquire about demonstrations and various applications.*