モレキュラーデバイスジャパン List of Products and Services

The "SpectraMax iD5e" is a product that enables advanced measurements in five detection modes: absorbance, fluorescence, luminescence, time-resolved fluorescence (TRF), and fluorescence polarization (FP). With its hybrid optical system, touchscreen interface, and temperature control features, it provides flexibility and accuracy for complex assays. Additionally, it offers over 200 preset protocols, including those compatible with our entire reagent suite, allowing for a variety of assays. 【Features】 ■ Excellent hybrid optical system ■ Simple data acquisition and analysis ■ Flexible temperature control ■ Ongoing support and service *For more details, please download the PDF or feel free to contact us.

• Other laboratory equipment and containers

The "SpectraMax iD3s" is an ideal solution for measuring absorbance, fluorescence, and luminescence. As an option, it can be upgraded with dual injection, environmental control (CO2/O2) for live cell assays, and advanced shaking capabilities. Additionally, the high-efficiency monochromator optical system combined with a super-cooled photomultiplier tube (PMT) enhances sensitivity, selectivity, and dynamic range while minimizing noise. 【Features】 ■ Excellent optical system ■ Simple data acquisition and analysis ■ Flexible temperature control ■ Ongoing support and service *For more details, please download the PDF or feel free to contact us.

• Other laboratory equipment and containers

The "QPix FLEX" is a laboratory system that can automate a series of tasks from plating to streaking, colony picking, and liquid handling. Equipped with a high-resolution color camera that identifies the shape and color of colonies, it achieves high-precision picking. With a compact size of W640mm × D550mm × H710mm, it can be installed in low-oxygen and anaerobic chambers, reducing the time spent on repetitive manual tasks and contributing to improved throughput and quality. 【Features】 - Automates each step of microbial screening. It supports labor-intensive liquid handling tasks such as media dispensing, glycerol addition, plating, and hit picking. - High-precision picking reduces rework and sample loss. - A replaceable tip system allows for compatibility with multiple varieties using a single unit. - Ensures traceability of each process and sample through 2D barcode reading. *For more details, please refer to the materials available for download in the catalog. Feel free to contact us with any inquiries.

• Microbiology
• Cell manipulation
• Other inspection equipment and devices

"ImageXpress HCS.ai" is a high-content screening system that inspires users' imagination with high-quality imaging and analysis, enabling them to easily obtain the data they need. It can be configured to meet the requirements of users and can be upgraded to adapt to the evolving needs of research. Empower your team to obtain high-resolution images and robust data from various 2D and 3D cell assays, and leverage the power of AI to gain deeper insights. 【Features】 ■ Addresses future lab needs ■ Access to insightful data ■ Ability to capture details of 2D and 3D biological models ■ Capability to gain deeper insights ■ Ability to obtain clearer images more quickly ■ Everything from image acquisition to data analysis can be done on a single platform *For more details, please download the PDF or feel free to contact us.

• Other inspection equipment and devices

"DispenCell" is a dispensing device developed for the rapid, easy, and gentle isolation of single cells. During dispensing, it is possible to prove the clonality of single cells. Its small footprint allows it to fit perfectly into various experimental environments, such as working within a sterile hood, routine plating on a benchtop, and existing automated workflows. Additionally, it features a simple interface for intuitive operation, easy setup, and requires no cleaning or calibration. [Features] ■ Gentle dispensing ■ Proof of clonality ■ High cloning efficiency ■ Compact ■ No contamination *For more details, please refer to the PDF document or feel free to contact us.

• Dispenser

The "ImageXpress Micro Confocal" is a unique and flexible high-content imaging system that can perform wide-field and confocal imaging with a single device. Thanks to its proprietary confocal technology, it is well-suited for acquiring and analyzing high-quality images of complex three-dimensional models such as spheroids, tissues, and OrganoPlates. When equipped with an optional immersion lens, it can capture even clearer images, enabling more quantitative analysis. 【Features】 - A high-sensitivity sCMOS camera with a wide dynamic range of over 3 logs, allowing for rapid acquisition of statistically significant data. - High-resolution cell images of three-dimensional models, improving quantitativeness. - An optical system utilizing proprietary AgileOptix technology, achieving high-quality imaging while maintaining throughput. *For more details, please refer to the PDF materials or feel free to contact us.

• Image analysis software

The "FLIPR Penta" is a high-throughput cell-based screening system developed to enhance the FLIPR platform for monitoring GPCRs and ion channels. With advanced high-speed cameras and Peak Pro2 software, it enables detailed measurement and analysis of calcium oscillations in human iPS cell-derived cardiomyocytes and neurons. It allows high-speed imaging at up to 100Hz and can quickly analyze oscillation patterns for over 30 peak parameters. 【Features】 ■ High-throughput screening for initial toxicity assessment ■ Highly scalable optical system ■ User-replaceable 96, 384, and 1536 well pipettors ■ Intuitive and user-friendly software ■ Internal plate handler for FLIPR Cycler *For more details, please refer to the PDF materials or feel free to contact us.

• Software (middle, driver, security, etc.)

The "SpectraMax Mini" is a microplate reader equipped with three detection modes: UV-Vis absorbance, fluorescence, and luminescence. Users can upgrade from two modes to three modes themselves, and the included software supports rapid data acquisition and analysis. With a compact body that can be placed anywhere, it offers a one-stop solution from measurement to analysis and reporting. It is capable of measuring small sample volumes using microplates. 【Features】 ■ Compact body that can be placed anywhere ■ One-stop solution from measurement to reporting ■ Highly versatile multi-mode detection ■ Absorbance measurement using a wavelength-adjustable monochromator ■ Capable of measuring small sample volumes with microplates *For more details, please refer to the PDF document or feel free to contact us.

• Other inspection equipment and devices

Organoids derived from iPS cells and tissue stem cells are expected to serve as advanced in vitro models for disease modeling and drug screening, as they mimic human tissue structure and function, thereby improving the clinical predictability of drug responses. However, challenges such as the complexity of sample preparation, reproducibility, and scalability hinder their practical application as a major screening method in drug discovery. To address this bottleneck in sample preparation, our product does not perform mechanical operations regularly; instead, AI machine learning automatically makes decisions based on monitoring results of the samples. Under a 24-hour operational environment, it appropriately conducts and manages medium exchanges and passaging, fully automating the complex workflow of the organoid culture process. As a result, we achieve significant reductions in costs and time, as well as a decrease in human error, while enhancing the productivity of the cell culture process in assays using iPS cells and organoids. *For detailed specifications, please refer to the PDF document or feel free to consult us.*

• Other Culture

The "ImageXpress Confocal HT.ai" is a high-content imaging system that enhances the image quality and throughput of assays for 3D organoids and spheroids, enabling observations that are difficult with other technologies. It achieves appropriate confocal imaging tailored to the sample using a high-output light source and dual spinning disks. With the immersion lens option, it captures bright images even at the depths of thick samples. 【Features】 ■ High-performance laser excitation light source ■ AgileOptix technology ■ Automatic water supply and drainage immersion lens option ■ IN Carta image analysis software *For more details, please refer to the PDF materials or feel free to contact us.

• Other information systems

"SoftMax Pro GxP" is a highly secure software that is fully compliant with FDA 21 CFR Part 11, maintaining data integrity through a streamlined workflow. It is optimized to simplify various operations, from controlling the microplate reader of molecular devices to data acquisition, analysis, and report generation. 【Features】 ■ Track and Record All Changes The system's audit trail tracks and records all changes, including timestamps, usernames, user IDs, section statements, signature information, and measurement results. ■ Achieve Secure Document Sharing Document data is stored in a Microsoft SQL database, enabling thoroughly managed document sharing with controlled access permissions. ■ Maintain Data Integrity By using a paperless document status system, data integrity can be maintained through electronic signatures and document workflows. *For more details, please refer to the PDF materials or feel free to contact us.

• Software (middle, driver, security, etc.)

The fluorescent microplate reader "Gemini EM/XPS" provides a flexible environment for setting appropriate excitation and measurement wavelengths for most fluorescence intensity assays. Equipped with dual monochromators, it allows you to experiment with new or novel dyes without the need to purchase expensive filter sets. Control of the device and data analysis are performed using the included SoftMax Pro software, enabling smooth data analysis without the need to export to other spreadsheet software. 【Features】 ■ Dual monochromator ■ No filters required ■ Top and bottom measurement ■ Higher sensitivity than well scanning ■ Validation tools for software and device *For more details, please refer to the PDF materials or feel free to contact us.

• Other research reagents

The "QPix400 Series" is a fully automated microbial colony picking system that screens markers in advance and allows for the picking of only the desired colonies. By combining white light and fluorescence, it screens valuable colonies and achieves high-speed, high-precision picking through its unique picking mechanism. This proven system has been delivered to over 600 pharmaceutical companies, universities, and public research institutions worldwide. 【Features】 ■ Automation of colony picking according to throughput ■ Easy and rapid colony screening ■ High-speed, high-precision picking ■ Consistent data management through barcodes ■ Prevention of contamination with customizable HEPA filters *For more details, please refer to the PDF document or feel free to contact us.

• Microbiology

"FLIPR Penta" is a cell-based kinetic assay system designed for the identification of initial leads for GPCRs and ion channels. It allows for configurations based on library size, detection mode, and screening format, facilitating a smooth transition from assay development to lead optimization. Simultaneous dispensing and measurement for all wells is possible, making it suitable for high-throughput screening. 【Features】 ■ Cell-based kinetic assay system ■ Simultaneous dispensing and measurement for all wells ■ Compatible with fluorescence and luminescence assays ■ System configuration adjustable according to the assay *For more details, please refer to the PDF materials or feel free to contact us.

• others

The "AquaMax 4000/2000" is a microplate washer that features a modular design with interchangeable heads. It offers various cleaning functions and is suitable for biochemical assays, including ELISA, as well as cell-based assays. The device is equipped with an automatic cleaning function to prevent issues caused by maintenance deficiencies. 【Features】 ■ Compatible with 96/384 well microplates ■ Easily interchangeable cleaning heads ■ Cell washing head for cell-based assays ■ Simultaneous aspiration and dispensing from all wells ■ Intuitive operation from a touch screen *For more details, please refer to the PDF document or feel free to contact us.

• Other cleaning equipment

The cell imaging system "ImageXpress Pico" is an automated cell imaging system that achieves time reduction and efficiency in image acquisition and analysis workflows. With just a few clicks after image analysis, you can easily generate heat maps, scatter plots, and bar graphs. It is equipped with options such as objective lenses, filters, reagent injectors, and environmental control modules to meet the needs of various laboratories. 【Features】 - Achieves time reduction and efficiency in image acquisition and analysis workflows - Easily generates heat maps, scatter plots, and bar graphs - Equipped with options such as objective lenses and filters - Meets the needs of various laboratories *For more details, please refer to the PDF document or feel free to contact us.

• Image Cytometer

This is a catalog for budget applications for microplate readers from Molecular Devices, a pioneer in microplate readers. It clearly introduces various models and prices, including absorbance, fluorescence, luminescence, multi-mode plate readers, and plate washers. You can easily see the measurement modes, compatibility with various applications, and options such as injectors at a glance. Please apply using the URL below. https://www.moleculardevices.co.jp/budget_catalog

• Analytical Equipment

The multi-mode microplate reader 'SpectraMax i3x' is equipped with absorbance, fluorescence, and luminescence measurement capabilities, and can continuously add a wider range of applications with dedicated cartridges. By adding cartridges for upgrades, it enables Western blotting, imaging, and high-speed kinetic measurements using reagent injectors. [Features] ■ High-sensitivity absorbance, fluorescence, and luminescence microplate reader ■ User-upgradable options ■ Streamlined data analysis with SoftMax Pro software ■ Easy application addition by simply inserting cartridges ■ Capable of cell imaging using bright field and fluorescence (Option: SpectraMax MiniMax 300) [Examples of dedicated cartridges] ScanLate Western blot detection AlphaScreen HTRF CisBio Certified Time-resolved fluorescence (TRF) Ex: 370 nm, Em: 616/642 nm Fluorescence polarization (FP) Fluorescein, Rhodamine BRET Auto dual injector

• Fluorescence spectrophotometer

The microplate reader "SpectraMax Paradigm" flexibly accommodates a variety of applications simply by adding or exchanging cartridges. It supports over 20 types of cartridges and custom cartridges, including absorbance, fluorescence, time-resolved fluorescence (TRF) including HTRF, fluorescence polarization, AlphaScreen, AlphaLISA, and luminescence. Each cartridge is equipped with a dedicated optical system, achieving highly sensitive detection comparable to dedicated devices. 【Features】 ■ Flexibly accommodates a variety of applications ■ Capable of measuring absorbance, fluorescence, and time-resolved fluorescence including HTRF ■ Achieves high sensitivity and a wide measurement range (fluorescence) ■ Compatible with 6-1536 wells ■ Upward and downward measurement ■ Automatic Z-axis height focus adjustment *For more details, please refer to the PDF document or feel free to contact us.

• Fluorescence spectrophotometer

The confocal HCS imaging system ImageXpress Micro Confocal employs unique confocal technology, making it an optimal high-content imaging system for three-dimensional cells and tissues. It enables the analysis of thick samples such as spheroids, organoids, and organs, which are difficult to examine with conventional fluorescence microscopes, as well as fine intracellular localization. Additionally, it can acquire images using 1536-well plates, allowing for higher throughput assays. 【Features】 ■ Acquire both conventional fluorescence images and confocal images with a single device ■ Switch between fluorescence and confocal images with one click ■ Capture confocal images at high speed ■ Long lifespan with no maintenance required ■ Equipped with a wide-field and high-sensitivity sCMOS camera ■ Capable of phase contrast imaging for bright field images and incubator integration ■ Easily execute image acquisition and analysis with software *For more details, please refer to the PDF materials or feel free to contact us.

• Microbiology

The SpectraMax ABS absorbance microplate reader allows for easy and rapid execution of various assays such as ELISA, microbial growth, and protein quantification. Equipped with an 8-channel reading head for quick measurements and featuring a patented PathCheck sensor. By using the PathCheck sensor, which is not affected by temperature, the depth of the sample solution corresponding to the optical path length is detected and automatically standardized, ensuring accurate absorbance values. 【Features】 ■ Wavelength selection by monochromator eliminates the need for purchasing or replacing filters ■ Compact design and reasonable price ■ Compatible with 96-well plates, achieving high throughput with small sample volumes ■ Powerful data analysis with industry-standard SoftMax Pro software ■ Performance optimization through validation tools

• Other protein analysis

The "FlexStation3 Microplate Reader" is a 5-mode multi-plate reader equipped with a liquid transfer system. With the built-in 8 or 16 channel pipetter, it automatically dispenses samples from a 96 or 384 well compound reagent plate to the measurement microplate, well by well. Dispensing volumes and concentrations can be set for each well, and since the dispensing is done directly from the plate, it reduces reagent consumption while allowing various assay conditions to be tested on a single plate, making it suitable for agonist-antagonist screening. 【Features】 ■ A 5-mode reader capable of fluorescence, absorbance, time-resolved fluorescence, fluorescence polarization, and luminescence for diverse applications ■ A flexible liquid transfer system that accommodates various assay protocols ■ User-configurable pipetting operations to establish and optimize measurement conditions ■ Equipment and software are compliant with validation requirements *For more details, please refer to the PDF document or feel free to contact us.

• Other photoanalytical instruments

This product is a system that has perfected image acquisition and analysis technology. Thanks to its agile design, high-speed image acquisition has become possible. It comes with an option to upgrade to a confocal system as needed. 【Features】 ■ Beautiful image acquisition and expandability with the addition of a confocal unit ■ Compatible with a wide range of applications through objective lenses from 1x to 100x and a customizable 5-position filter cube ■ Fast data acquisition with a wide field of view and a broad dynamic range ■ Expand applications by adding a bright field unit, liquid dispensing mechanism, and environmental control unit *For more details, please refer to the PDF document or feel free to contact us.

• Image Cytometer

This product is a dedicated option system that enables visualization and analysis of cells on the SpectraMax i3x multi-mode microplate reader. With a simple workflow, it allows for cell recognition in bright field and imaging using green and red fluorescence channels. Additionally, since upgrades can be performed on the customer site, imaging analysis with the microplate reader can be achieved without investing in complex microscope systems. 【Features】 - Consolidates cell imaging and microplate reader assays into a single workflow - Measures non-stained cell counts and confluency using StainFree technology - Enables viability assessment and toxicity assays through multi-channel functionality - Quickly and easily captures and analyzes images with SoftMax Pro software *For more details, please refer to the PDF document or feel free to contact us.

• Image analysis software

The "ScanLater Western Blot Detection System" can be installed on the SpectraMax i3x and Paradigm detection platforms. Without the need to invest in a dedicated system, the ScanLater Western Blot Detection Cartridge can be attached in just a few minutes, adding detection capabilities. 【Features】 ■ Western blot detection with a microplate reader ■ Enhanced signal stability with a substrate-free method ■ Expanded dynamic range without the need for cumbersome optimization *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices

This is a stacker system for tabletop microplate readers. It can be operated with SoftMax Pro microplate data acquisition and analysis software, providing an easy-to-use environment for both beginners and experienced users. There are options for 20, 40, and 50 plate magazines and a barcode reader. 【Features】 ■ Integration with SPECTRAMAX readers is possible ■ Robust and highly reliable ■ Easy setup and use ■ Flexible operation ■ Extends the power of SOFTMAX PRO *For more details, please refer to the PDF materials or feel free to contact us.

• Other photoanalytical instruments

The "SpectraMax Paradigm" is a revolutionary multi-mode microplate reader that features a design (patent pending) allowing researchers to easily configure the system themselves. With this cartridge system, you can select and use only the necessary cartridges. Even if you change the detection method, you can achieve the desired detection simply by adding a new cartridge while keeping the device unchanged. 【Features】 ■ Achieves extremely high sensitivity detection ■ Over 20 types of cartridges and custom cartridges ■ Upward/downward measurement and automatic z-axis height adjustment ■ No gain adjustment needed during fluorescence measurement ■ Capable of measuring sample concentrations up to 7 digits in a single measurement *For more details, please refer to the PDF materials or feel free to contact us.

• Other microscopes and optical inspection equipment

"ClonePix2" is an automated animal cell picking system that efficiently picks high-yielding clones of antibody drug candidates and other proteins. It captures images of cell colonies using white light and fluorescence. By ranking the individually identified colonies based on fluorescence intensity through image analysis, efficient screening can be performed. Customization is also possible to automatically screen and pick high-yielding clones derived from single cells. 【Features】 ■ High-efficiency colony picking system utilizing imaging capabilities ■ Colonies identified using a unique image analysis algorithm ■ Multi-channel image analysis using various fluorescence filters ■ Total solution including media and reagents ■ Customization allows for a streamlined workflow from identifying single cells to screening for production capability. *For more details, please refer to the PDF materials or feel free to contact us.

• Animal cells

The "CloneSelect Imager" that we handle quickly measures cell confluency using white transmitted light imaging. Regardless of the number of wells in the microplate, the measurement time for one plate is less than 90 seconds. Measurements can be taken with the plate covered, allowing it to be returned to the incubator for continued culture after measurement. By evaluating colony formation retrospectively, it is easy and accurate to determine monoclonality. 【Features】 ■ Rapid image acquisition with easy-to-use software ■ Objective and quantitative evaluation of cell proliferation ■ Tracking the process of colony formation ■ Support from imaging to analysis and reporting *For more details, please refer to the PDF document or feel free to contact us.

• Other cell research

The "QPix 400 Series" is an automated microbial colony picking system that enables consistent data management through barcodes. It allows for the detection of colonies while simultaneously quantifying fluorescent labels, enabling screening of colonies that produce the target protein before picking. Its unique picking mechanism achieves high-speed and high-precision picking. 【Features】 ■ Automation of colony picking according to throughput ■ Screening of valuable colonies by combining white light and fluorescence ■ High-speed and high-precision picking ■ Consistent data management through barcodes ■ Prevention of contamination with a customizable HEPA filter *For more details, please refer to the PDF materials or feel free to contact us.

• Analysis Equipment