ITWジャパン List of News Articles

A world where miniaturization and high performance are advancing daily. Mobile phones now have features that were unimaginable just a few years ago. The realization of such high performance is thanks to thin film technology, which is utilized in a wide range of applications as follows: 【Applications of Thin Film Technology】 - Microelectronics - Anti-reflective coatings for glass - Antibacterial metal coatings for medical devices - Flexible solar cells Thin film technology is defined as "the process of creating, coating, and processing thin film materials on a substrate surface." We are currently publishing basic knowledge materials on glass coatings for the glass industry! ⚫ Glass Coatings ⚫ What is Low-E Glass? ⚫ Laminating and Materials of Low-E Coatings ⚫ Application Requirements ⚫ What is Low-E Coating Technology? ⚫ Glass Coating Market Please take a moment to read it. https://mono.ipros.com/news/detail/129167/

Brooks has added a mass flow controller specifically designed for bioprocesses to its range of general-purpose mass flow controllers. In this article, we will introduce this product and its distinctive advantages. 1. One MFC can cover the necessary spare parts for each type of gas. 2. With a control range of 1:250, it enables high-precision and accurate flow control, reducing the number of MFCs needed. 3. It accommodates a wide range of bioreactor needs, from benchtop types to large stainless steel tanks. There is a wealth of adoption experience for both single-use and multi-use applications. For more detailed product specifications, case studies, and advantages, please feel free to contact us. A representative well-versed in flow control and bioreactors will assist you.

Hot Melt Extrusion (HME) is a method that uses heat and pressure to melt polymers and extrude them into molds in a continuous process. HME is widely applied in the plastics industry and has recently been used in pharmaceutical formulations and drug delivery systems. The HME process is used to mix active pharmaceutical ingredients (APIs) with polymers and other excipients at high temperatures and pressures. The extruded material can be cut or crushed into micro-pellets for filling into capsules or compressing into tablets. Highlights: Measurement and control of mass flow rate of supercritical CO2 Achieving accurate flow rates even at low temperatures (below -30°C) Process Solution: Due to the high reliability of Brooks Instrument's Quantim Coriolis mass flow measurement and control for fluids, systems using this mass flow can measure and control the mass flow rate of the liquid CO2 being injected, rather than the pump's operating speed. In the HME process, when CO2 is maintained above its critical temperature and critical pressure, it enters a supercritical state.

In the EtherNer/IP model, when scaling up a system built at a desktop research lab level to manufacturing level, it is relatively easy to implement specification changes from single control to recipe control. The SLA5800 series is available in a flow range from 3cc/min to a maximum of 2500L/min, allowing for scaling up by adjusting parameters to match the maximum capacity using recipes and interfaces. When replacing or adding MFCs in the evaluation system, it can be done simply with just a LAN cable and a power cable, without the need for additional hardware. This not only contributes to flexible system changes but also significantly improves space efficiency and maintainability. At the same time, IoT integration is also possible. Remote operation can be incorporated on a PC basis with a low barrier to implementation. The SLA5800 series bio package uses FDA-compliant elastomers. It is capable of providing documentation and evidence, while also increasing the shielding rate during valve closure compared to conventional products, enabling more precise adjustments of dissolved oxygen (DO) levels, particularly in oxygen control. ITW Japan Co., Ltd. Brooks Instrument

In the manufacturing process of active pharmaceutical ingredients for biopharmaceuticals, including antibody drugs and vaccines, the goal is to culture and scale up biological entities such as viruses and cells, necessitating the creation of an environment conducive to the survival of the target organisms. The research and development department continuously seeks the optimal conditions for each type of cell or virus, which involves adjusting the flow rates of air, oxygen, nitrogen, and carbon dioxide to achieve optimal concentrations. Additionally, it is crucial to maintain a stable environment by adjusting the flow rates of each gas in response to monitoring results of pH and dissolved oxygen concentration. Particularly for oxygen, even small flow rates can lead to a rapid increase in dissolved oxygen concentration, requiring precise control of the flow rates. The SLA5800 series has a proven track record in many culture devices and facilities, continuing from the previous generation 5800E/i series, and is a stable product line with a large number of units shipped and consistent maintenance continuity. ITW Japan Co., Ltd. Brooks Instrument

The importance of gas flow control and mass flow controllers in the manufacturing of biopharmaceuticals, including antibody drugs, has been frequently introduced. This time, we will introduce the applications of mass flow controllers/flow meters in medical devices. In the manufacturing and control of respiratory-related medical devices, flow meters and mass flow controllers are utilized. The key factor is to maintain the appropriate ratio of oxygen and carbon dioxide concentrations in the respiratory gas, optimizing blood concentrations. It is necessary to precisely adjust and supply the gas flow of air/oxygen. The requirements include the ability to adjust gas flow to maintain appropriate concentrations in the respiratory gas and the functionality to mix/blend. Additionally, it is important to ensure that appropriate materials are used for medical devices/equipment. For gas blending applications, we offer a range of products including area flow meters (including those with valves), the SLA5850 series mass flow controllers, and the SLA5850 Biotech package, which comes pre-installed with the required four types of gas calibration data and uses materials compliant with USP standards. ITW Japan Co., Ltd. Brooks Instrument

The VDM300, designed for advanced stripping and passivation processes after metal etching, achieves superior accuracy, high flow rates, a wide control range, and low power consumption compared to flash vaporization systems. Features of the VDM300: 1. Flow range: 3 slpm (DIW vapor) 2. Direct steam measurement for excellent flow accuracy 3. Direct connection to the plant's pure water supply system 4. Operable even at minimum temperature (non-heated state) 5. Optimally designed for rinsing and drainage 6. EtherCAT digital communication 7. Brooks Expert Support Tool (BEST) graphical interface