ITWジャパン List of News Articles

In the EtherNer/IP model, when scaling up a system built at a desktop research lab level to manufacturing level, it is relatively easy to implement specification changes from single control to recipe control. The SLA5800 series is available in a flow range from 3cc/min to a maximum of 2500L/min, allowing for scaling up by adjusting parameters to match the maximum capacity using recipes and interfaces. When replacing or adding MFCs in the evaluation system, it can be done simply with just a LAN cable and a power cable, without the need for additional hardware. This not only contributes to flexible system changes but also significantly improves space efficiency and maintainability. At the same time, IoT integration is also possible. Remote operation can be incorporated on a PC basis with a low barrier to implementation. The SLA5800 series bio package uses FDA-compliant elastomers. It is capable of providing documentation and evidence, while also increasing the shielding rate during valve closure compared to conventional products, enabling more precise adjustments of dissolved oxygen (DO) levels, particularly in oxygen control. ITW Japan Co., Ltd. Brooks Instrument

In the manufacturing process of active pharmaceutical ingredients for biopharmaceuticals, including antibody drugs and vaccines, the goal is to culture and scale up biological entities such as viruses and cells, necessitating the creation of an environment conducive to the survival of the target organisms. The research and development department continuously seeks the optimal conditions for each type of cell or virus, which involves adjusting the flow rates of air, oxygen, nitrogen, and carbon dioxide to achieve optimal concentrations. Additionally, it is crucial to maintain a stable environment by adjusting the flow rates of each gas in response to monitoring results of pH and dissolved oxygen concentration. Particularly for oxygen, even small flow rates can lead to a rapid increase in dissolved oxygen concentration, requiring precise control of the flow rates. The SLA5800 series has a proven track record in many culture devices and facilities, continuing from the previous generation 5800E/i series, and is a stable product line with a large number of units shipped and consistent maintenance continuity. ITW Japan Co., Ltd. Brooks Instrument

The importance of gas flow control and mass flow controllers in the manufacturing of biopharmaceuticals, including antibody drugs, has been frequently introduced. This time, we will introduce the applications of mass flow controllers/flow meters in medical devices. In the manufacturing and control of respiratory-related medical devices, flow meters and mass flow controllers are utilized. The key factor is to maintain the appropriate ratio of oxygen and carbon dioxide concentrations in the respiratory gas, optimizing blood concentrations. It is necessary to precisely adjust and supply the gas flow of air/oxygen. The requirements include the ability to adjust gas flow to maintain appropriate concentrations in the respiratory gas and the functionality to mix/blend. Additionally, it is important to ensure that appropriate materials are used for medical devices/equipment. For gas blending applications, we offer a range of products including area flow meters (including those with valves), the SLA5850 series mass flow controllers, and the SLA5850 Biotech package, which comes pre-installed with the required four types of gas calibration data and uses materials compliant with USP standards. ITW Japan Co., Ltd. Brooks Instrument

The VDM300, designed for advanced stripping and passivation processes after metal etching, achieves superior accuracy, high flow rates, a wide control range, and low power consumption compared to flash vaporization systems. Features of the VDM300: 1. Flow range: 3 slpm (DIW vapor) 2. Direct steam measurement for excellent flow accuracy 3. Direct connection to the plant's pure water supply system 4. Operable even at minimum temperature (non-heated state) 5. Optimally designed for rinsing and drainage 6. EtherCAT digital communication 7. Brooks Expert Support Tool (BEST) graphical interface

When using a thermal mass flow meter, it is very important to understand its measurement principle. Setting high-precision and stable process conditions is not only essential but also very beneficial for troubleshooting and early detection. The sensor consists of a heater (H) placed in the center of the tube and temperature sensors (T1 and T2) positioned equidistantly on either side. The heater is continuously supplied with properly controlled power, generating heat. When there is no flow in the sensor tube, the heat from the heater is evenly transferred to temperature sensors T1 and T2, resulting in both being at the same temperature. However, when there is flow in the direction indicated by the arrows in the diagram, the fluid carries heat away from T1, causing its temperature to drop, while T2 receives heat, resulting in a temperature increase. The resulting temperature difference between T1 and T2 becomes a function of the mass flow rate of the fluid within the sensor tube. This is processed appropriately and output as an electrical signal representing the mass flow rate. (This is an excerpt from the original text.) https://www.youtube.com/watch?v=XKpX3rrt1qc [ITW Japan Co., Ltd. Brooks Instrument]