Polysphere Co., Ltd. List of Products and Services

"Uni-spheres" are spherical polystyrene-based latex particles with excellent uniformity, suitable for calibration and precision management of particle size measurement devices, as well as for validating particle size measurement methods. The particle size is determined using the particle size calibration service of the National Metrology Institute of Japan (NMIJ) and is traceable to the International System of Units (SI). 【Specifications】 ■ Form: Aqueous dispersion of polystyrene particles (containing 0.5 mg/ml of sodium azide) ■ Volume: 10 ml ■ Solid concentration: 10 mg/ml *For more details, please download the PDF or feel free to contact us.

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The main raw materials used in the latex agglutination method are latex particles and antibodies. Antibodies are often uniquely manufactured by each company, and the size of the latex particles selected varies depending on the test items. Our company offers a variety of latex particles with different particle sizes to meet testing needs, providing high quality and reproducibility. Additionally, our latex manufacturing technology has received high acclaim from third parties, including being adopted as standard particles by the National Institute of Advanced Industrial Science and Technology. Leveraging our years of experience in manufacturing latex for in vitro diagnostic reagents, we have a robust quality control system that includes lot management. *For more details, please download the PDF or feel free to contact us.*

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Our medical latex particles are high-precision microparticles used in the latex agglutination method for in vitro diagnostic reagents. Polystyrene latex produced by the soap-free method excels in uniformity and dispersibility, supporting stable detection reactions. To accommodate physical adsorption and chemical bonding methods, we offer Plain and COOH types. The COOH type provides three levels of COOH group particles with nearly the same particle size, allowing for the selection of particles suitable for the characteristics of antibodies. With many years of experience in manufacturing latex for in vitro diagnostic reagents, we have ample experience in lot management and other related areas. *For more details, please download the PDF or feel free to contact us.*

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"Hi・spheres COOH_High" is a latex particle manufactured for in vitro diagnostic use through soap-free polymerization. Latex particles produced using this technology do not use surfactants at all during the process, making them excellent for the adsorption and binding of biomolecules such as antibodies. For the chemical bonding type, the amount of carboxyl groups can be selected from three levels. Please feel free to contact us when you need assistance. 【Features】 ■ Excellent adsorption and binding of biomaterials ■ Suppresses aggregation of latex particles during the sensing process ■ Good re-dispersibility through ultrasonic dispersion ■ Available in two types: physical adsorption type and chemical bonding type ■ For the chemical bonding type, the amount of carboxyl groups can be selected from three levels (with nearly the same particle size; initial consideration recommends Low) *For more details, please download the PDF or feel free to contact us.

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"Hi・spheres COOH_Middle" is a latex particle manufactured using soap-free polymerization for in vitro diagnostic use. It excels in the adsorption and binding of biological substances, suppresses the aggregation of latex particles in the detection process, and features good re-dispersibility through ultrasonic dispersion. We also support users who are unfamiliar with standard antibody detection protocols. Please feel free to contact us if you have any requests. 【Features】 ■ Excellent adsorption and binding of biological substances ■ Suppresses aggregation of latex particles in the detection process ■ Good re-dispersibility through ultrasonic dispersion ■ Available in two types: physical adsorption type and chemical bonding type ■ The chemical bonding type offers three levels of carboxyl group content (with nearly identical particle size; Low is recommended for initial considerations) *For more details, please download the PDF or feel free to contact us.

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"Hi・spheres COOH_Low" is a latex particle manufactured for in vitro diagnostic use through soap-free polymerization. Due to special modifications on the particle surface, it suppresses the aggregation of latex particles during the sensing process and allows for smooth re-dispersion even after ultrasonic dispersion post-centrifugation. Two types are available: physical adsorption type and chemical bonding type. The chemical bonding type offers three levels of carboxyl group amounts to choose from. 【Features】 ■ Excellent adsorption and binding of biomaterials ■ Suppresses aggregation of latex particles during the sensing process ■ Good re-dispersibility through ultrasonic dispersion ■ Available in two types: physical adsorption type and chemical bonding type ■ The chemical bonding type allows selection from three levels of carboxyl group amounts (with nearly identical particle sizes; Low is recommended for initial consideration) *For more details, please download the PDF or feel free to contact us.

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"Hi・spheres Plain" is a latex particle manufactured for in vitro diagnostic use through soap-free polymerization. Latex particles produced using this technology do not use surfactants at all during the process, which enhances their ability to adsorb and bind biomolecules such as antibodies. Additionally, special modifications to the particle surface suppress the aggregation of latex particles during the sensing process, allowing for smooth re-dispersion even after centrifugation and ultrasonic dispersion. 【Features】 ■ Excellent adsorption and binding of biomaterials ■ Suppression of latex particle aggregation during the sensing process ■ Good re-dispersibility through ultrasonic dispersion ■ Available in two types: physical adsorption type and chemical bonding type ■ The chemical bonding type offers three levels of carboxyl group content (with nearly identical particle size; initial studies recommend Low) *For more details, please download the PDF or feel free to contact us.

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"Uni-spheres" are newly developed particle size calibration standard particles based on soap-free polymerization technology cultivated in the development of latex for in vitro diagnostic reagents. They are uniform, spherical polystyrene-based latex particles that can be used for the calibration and precision management of particle size measurement devices, as well as for the validation of particle size measurement methods. The particle size is determined using the particle size calibration service of the National Metrology Institute of Japan (NMIJ) and is traceable to the International System of Units (SI). 【Specifications】 ■ Form: Aqueous dispersion of polystyrene particles (containing 0.5 mg/ml of sodium azide) ■ Volume: 10 ml ■ Solid concentration: 10 mg/ml ■ CV value (reference): 1.0% ■ Density (reference): 1.0540 g/cm3 ■ Particle mass (reference): 4.916 fg *For more details, please download the PDF or feel free to contact us.

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