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Polysphere Co., Ltd.

addressIbaraki/Tsukuba-shi/4-19-1 Midorigahara X/S WORKSITE
phone050-3613-0667
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last updated:Nov 07, 2025
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体外診断薬用粒子 体外診断薬用粒子
標準粒子 標準粒子
体外診断薬用粒子

体外診断薬用粒子

ポリスフェア社の「Hi・spheres」は、ソープフリー重合で製造された体外診断薬用のラテックス粒子です。この技術により製造されたラテックス粒子は、その過程で界面活性剤を全く使用しないため、抗体など生体分子の吸着や結合に優れています。また粒子表面への特殊な修飾により、感さ工程でのラテックス粒子の凝集を抑制し、遠心分離後の超音波分散においてもスムーズな再分散が可能です。

Medical latex particles for in vitro diagnostic reagents

Providing technology that supports the reliability of diagnostic drugs with high-precision latex particles. It is also adopted by the National Institute of Advanced Industrial Science and Technology as standard particles.

Our medical latex particles are high-precision microparticles used in the latex agglutination method for in vitro diagnostic reagents. Polystyrene latex produced by the soap-free method excels in uniformity and dispersibility, supporting stable detection reactions. To accommodate physical adsorption and chemical bonding methods, we offer Plain and COOH types. The COOH type provides three levels of COOH group particles with nearly the same particle size, allowing for the selection of particles suitable for the characteristics of antibodies. With many years of experience in manufacturing latex for in vitro diagnostic reagents, we have ample experience in lot management and other related areas. *For more details, please download the PDF or feel free to contact us.*

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Reagents suitable for the latex agglutination method.

Latex particles designed for in vitro diagnostic reagents, ensuring stable supply and quality.

The main raw materials used in the latex agglutination method are latex particles and antibodies. Antibodies are often uniquely manufactured by each company, and the size of the latex particles selected varies depending on the test items. Our company offers a variety of latex particles with different particle sizes to meet testing needs, providing high quality and reproducibility. Additionally, our latex manufacturing technology has received high acclaim from third parties, including being adopted as standard particles by the National Institute of Advanced Industrial Science and Technology. Leveraging our years of experience in manufacturing latex for in vitro diagnostic reagents, we have a robust quality control system that includes lot management. *For more details, please download the PDF or feel free to contact us.*

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Latex for In Vitro Diagnostic Reagents "Hi-spheres Plain"

Preliminary samples are also available! Support for inexperienced users with standard antibody sensitivity protocols.

"Hi・spheres Plain" is a latex particle manufactured for in vitro diagnostic use through soap-free polymerization. Latex particles produced using this technology do not use surfactants at all during the process, which enhances their ability to adsorb and bind biomolecules such as antibodies. Additionally, special modifications to the particle surface suppress the aggregation of latex particles during the sensing process, allowing for smooth re-dispersion even after centrifugation and ultrasonic dispersion. 【Features】 ■ Excellent adsorption and binding of biomaterials ■ Suppression of latex particle aggregation during the sensing process ■ Good re-dispersibility through ultrasonic dispersion ■ Available in two types: physical adsorption type and chemical bonding type ■ The chemical bonding type offers three levels of carboxyl group content (with nearly identical particle size; initial studies recommend Low) *For more details, please download the PDF or feel free to contact us.

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Latex for in vitro diagnostic reagents "Hi-spheres COOH_Low"

Since no surfactants are used at all, it excels in the adsorption and binding of biomolecules such as antibodies!

"Hi・spheres COOH_Low" is a latex particle manufactured for in vitro diagnostic use through soap-free polymerization. Due to special modifications on the particle surface, it suppresses the aggregation of latex particles during the sensing process and allows for smooth re-dispersion even after ultrasonic dispersion post-centrifugation. Two types are available: physical adsorption type and chemical bonding type. The chemical bonding type offers three levels of carboxyl group amounts to choose from. 【Features】 ■ Excellent adsorption and binding of biomaterials ■ Suppresses aggregation of latex particles during the sensing process ■ Good re-dispersibility through ultrasonic dispersion ■ Available in two types: physical adsorption type and chemical bonding type ■ The chemical bonding type allows selection from three levels of carboxyl group amounts (with nearly identical particle sizes; Low is recommended for initial consideration) *For more details, please download the PDF or feel free to contact us.

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Latex "Hi-spheres COOH_Middle"

Control the particle size of each lot! For the chemical bonding type, the amount of carboxyl groups can be selected from three levels.

"Hi・spheres COOH_Middle" is a latex particle manufactured using soap-free polymerization for in vitro diagnostic use. It excels in the adsorption and binding of biological substances, suppresses the aggregation of latex particles in the detection process, and features good re-dispersibility through ultrasonic dispersion. We also support users who are unfamiliar with standard antibody detection protocols. Please feel free to contact us if you have any requests. 【Features】 ■ Excellent adsorption and binding of biological substances ■ Suppresses aggregation of latex particles in the detection process ■ Good re-dispersibility through ultrasonic dispersion ■ Available in two types: physical adsorption type and chemical bonding type ■ The chemical bonding type offers three levels of carboxyl group content (with nearly identical particle size; Low is recommended for initial considerations) *For more details, please download the PDF or feel free to contact us.

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Latex "Hi-spheres COOH_High"

Excellent re-dispersibility through ultrasonic dispersion! Available in two types: physical adsorption type and chemical bonding type.

"Hi・spheres COOH_High" is a latex particle manufactured for in vitro diagnostic use through soap-free polymerization. Latex particles produced using this technology do not use surfactants at all during the process, making them excellent for the adsorption and binding of biomolecules such as antibodies. For the chemical bonding type, the amount of carboxyl groups can be selected from three levels. Please feel free to contact us when you need assistance. 【Features】 ■ Excellent adsorption and binding of biomaterials ■ Suppresses aggregation of latex particles during the sensing process ■ Good re-dispersibility through ultrasonic dispersion ■ Available in two types: physical adsorption type and chemical bonding type ■ For the chemical bonding type, the amount of carboxyl groups can be selected from three levels (with nearly the same particle size; initial consideration recommends Low) *For more details, please download the PDF or feel free to contact us.

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