FullStem Co. Ltd. List of Products and Services

■Features - Automated culture system accepted under the second type of regenerative medicine provision plan (osteoarthritis of the knee) ■Cell Type Adherent cells ■Cell Processing Capacity For adipose-derived mesenchymal stem cells, it is possible to culture up to 6*10^9 cells (600 million cells) in about 40 days (after 2 passages) (iPS cells can be cultured in amounts 10 times greater) ■Simultaneous Culture of Multiple Samples Not supported (it is possible to culture the required number of cells for multiple uses at once) ■Culture Period The doubling time of the cells remains the same as in general culture methods, but the cell count will reach 10 times the initial amount in about 10 days. ■Cell Quality Since the culture method does not involve constant stirring, there is no fluid stress, and there are no changes in cell quality. Our research has confirmed the following: - Maintenance of stem cell markers and retention of differentiation potential - No enlargement of cell diameter or aging phenomena - No chromosomal changes that could lead to tumorigenesis, and no tumor formation after transplantation ■Cell Recovery Rate and Viability Over 90% ■Adjustment of Cultured Cell Numbers It is possible to adjust the number of cells by modifying the amount of non-woven fabric that serves as the cell scaffold.

• Culture Equipment