オンチップ・バイオテクノロジーズ List of Products and Services

We are broadcasting the fifth installment of our webinar held on May 28, 2021. We invited the group leader from the Biomedical Research Division of the National Institute of Advanced Industrial Science and Technology to give a lecture. A roundtable discussion with our representatives was also conducted. In addition, we have various webinars from the past available for viewing. Please take a look. 【Lecture Content】 ■Lecture 1: Introduction to Onchip products and applications ■Lecture 2: "High-throughput technology for microbial exploration and acquisition using water-in-oil (w/o) droplets" ■Discussion: Roundtable discussion between the research group leader and our representatives ■Date and Time: May 28, 2021 (Friday) from 16:00 to 17:00 *For more details, please refer to the PDF document or feel free to contact us.

• Technical Seminar

We are broadcasting the fourth webinar hosted by our company, which took place on January 7, 2021. We invited a lecturer from the Fermentation Science Laboratory at Nagaoka University of Technology to give a presentation on "Cultivating, activating, and screening the 99.9...% of microorganisms yet to be discovered." A roundtable discussion between the lecturer and our company representatives was also held. Please take a look. 【Presentation Details】 ■ Presentation 1: Introduction to Onchip products and applications ■ Presentation 2: "Cultivating, activating, and screening the 99.9...% of microorganisms yet to be discovered" ■ Discussion: Roundtable with the lecturer and our company representatives ■ Date and Time: January 7, 2021 (Thursday) from 16:00 to 17:00 *For more details, please refer to the PDF document or feel free to contact us.

• Technical Seminar

We are broadcasting the third webinar hosted by our company, which took place on October 9, 2020. We invited a lecturer from Keio University’s Advanced Biosciences Research to conduct a lecture. A roundtable discussion with our company representatives was also held. In addition, we are offering various webinars that have been conducted in the past. Please take a look. 【Lecture Content】 ■Lecture 1: Introduction to Onchip Products and Applications ■Lecture 2: "Metabologenomics Approach Towards Understanding Gut Microbiome Function" ■Discussion: Roundtable with the lecturer and our company representatives ■Date and Time: October 9, 2020 (Friday) from 16:00 to 17:00 *For more details, please refer to the PDF document or feel free to contact us.

• Technical Seminar

We are broadcasting the second webinar hosted by our company, which took place on August 6, 2020. The presentation topic is "Development of Single Cell High-Throughput Screening Technology Utilizing Water-in-Oil Droplets and Gel Microdroplets." Our Head of Application Development will provide an explanation. In addition, we are also broadcasting various webinars that have been held in the past. Please take a look. 【Presentation Content】 ■Presentation 1: Technical Introduction and Application of Onchip Products ■Presentation 2: "Development of Single Cell High-Throughput Screening Technology Utilizing Water-in-Oil Droplets and Gel Microdroplets" ■Q&A: Answers to questions by our representatives ■Date and Time: August 6, 2020 (Thursday) from 16:00 to 17:00 *For more details, please refer to the PDF document or feel free to contact us.

• Technical Seminar

The "On-chip(R) Droplet Selector" is the world's only device capable of rapidly analyzing, separating, and dispensing single droplets, such as water droplets containing a large number of encapsulated cells and microorganisms. Its innovation and usefulness have been recognized, and it received the "Minister of Small and Medium Enterprises Award" for first place in the Excellent New Technology and New Product Award for Small and Medium Enterprises in April 2024. By reducing the labor and time required for screening, it significantly improves efficiency, bringing innovation to cell and microorganism screening. Compared to traditional methods using microplates, it enables a throughput that is 1,000 times greater. 【Features】 ■ Dispenses droplets collected in a microfluidic chip ■ Separates target droplets one by one through air pressure control ■ Capable of analyzing not only droplets but also cells and GMD (gel microdroplets) ■ The air inside the device is always clean due to a HEPA filter ■ The working environment can be controlled by enclosing it in a special anaerobic chamber *For more details, please refer to the PDF document or feel free to contact us.

• Separation device

The On-chip Droplet generator allows for the easy production of W/O emulsions. It can easily encapsulate cells, intestinal bacteria, environmental microorganisms, protozoa, DNA, beads, and more. *An optional temperature control feature is available, enabling the production of gel balls as well. ■Stable and uniform droplets can be produced By using our proprietary disposable microfluidic chip, stable and uniform droplets can be created. ■Droplet size can be adjusted through easy pressure control By controlling the pressure applied to the sample and oil, the size of the produced droplets can be adjusted. ■Observation of droplets during production is possible with the observation unit Using the included observation unit, droplets can be observed after production.

• Chemicals
• Separation device
• incubator

"On-chip Sort" is a flow cell exchange-type cell sorter. It adopts a unique cell separation method that controls the flow within a microfluidic chip. It allows sorting without damaging cells, making it possible to sort large cells such as stress-sensitive cells and spheroids. Emulsion analysis and separation using oil are also possible. It is a product that is compact yet thoroughly prioritizes user safety. Additionally, we also offer the flow cytometer "On-chip Flow," which can be upgraded to "On-chip Sort." 【Features】 ■ Separates cells without damage ■ Aseptic, contamination-free cell separation ■ Capable of separating and analyzing spheroids and emulsions in oil ■ Allows repeated sorting of samples ■ Compact ■ Easy operation, biohazard compliant *For more details, please refer to the PDF materials or feel free to contact us.

• Analytical Equipment and Devices
• Cleaning agents
• Other environmental analysis equipment

The "On-chip T buffer" is a cell wash and recovery solution that includes a cell non-toxic through-pass, preventing cell loss due to processes such as cell washing and leukocyte separation from peripheral blood. Simply coating chips or tubes with this product can prevent loss due to cell adhesion. It minimizes losses from cell washing and can be used as a washing solution for various applications. [Examples of Use] ■ Cell washing solution for various analyses ■ Washing solution during leukocyte separation ■ Cell staining solution ■ Adding about 0.5% BSA further prevents loss and acts as a blocking agent *For more details, please refer to the PDF document or feel free to contact us.

• Cleaning agents

The "on-chip SPiS" is capable of determining how many cells are present in a small pipette (0.3μl suction) using image recognition, and can dispense them accordingly. If the number of cells cannot be confirmed, the suction operation will be repeated until one cell is confirmed, after which dispensing will begin. It allows for easy and flexible usage, such as dispensing one cell at a time into each well of a well plate or dispensing multiple cells. 【Features】 ■ Easily and reliably dispense 1 or more cells into a well plate ■ Simple operation ■ Disposable pipette tip dispensing method ■ Automatic dilution function + image recognition with CCD camera ■ Affordable price *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

"On-chip Flow" is a flow cytometer with a flow cell exchange system. In addition to manipulating cells with minimal pressure, it improves microfluidic chip design and processing speed. It is a product that is compact to the utmost while thoroughly pursuing user safety. We also offer a cell sorter called "On-chip Sort" that separates cells in a small volume, in a sterile manner, and without damage. 【Features】 ■ Separates cells without damage ■ Sterile, contamination-free cell separation ■ Capable of separating and analyzing spheroids and emulsions in oil ■ Allows for repeated sorting of samples ■ Compact ■ Easy operation, biohazard compliant *For more details, please refer to the PDF materials or feel free to contact us.

• Other physicochemical equipment

In recent years, water-in-oil (w/o) droplets have been utilized in the field of genetic analysis, such as digital PCR (ddPCR) and next-generation sequencing (NGS), with each droplet serving as a small reaction system. This document provides detailed information on the principles of the "On-chip Droplet Generator," examples of emulsion encapsulation, specifications, and more. [Contents] ■ Principles of the On-chip Droplet Generator ■ Examples of emulsion encapsulation using the On-chip Droplet Generator ■ Applications of the On-chip Droplet Generator and On-chip Sort ■ A Water-in-Oil Emulsion Droplet Generator with Full Potential *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment