ブルカージャパン List of Products and Services

■ Low cost per sample, around several dozen yen ■ 7854 types. Original library can be expanded and shared ■ Identification of 1 sample in 11 minutes, 96 samples in 100 minutes using the smear method (※standard case) ■ Samples: bacteria, yeast, molds, etc. ■ Established protocols for filamentous fungi and acid-fast bacteria ■ Equipment used: microflex LT, microflex LT smart MALDI-TOF mass spectrometer

• Analytical Equipment and Devices

■ Low cost of approximately 400 yen per sample ■ Applicable to various microbial species (general bacteria, yeasts, etc.) ■ Results can be analyzed within 3 hours with a simple procedure (standard case) ■ Supports differentiation between strains of the same species ■ Allows for free selection of analysis areas ■ Typing analysis such as serotype differentiation is possible with the learning function of artificial intelligence ■ New analysis methods can be created using the differential display function of analysis areas ■ Equipment used: Microbial strain typing system IR Biotyper

• Analytical Equipment and Devices

■ Low cost per sample, around several dozen yen ■ 4274 types of general bacteria (Gram-negative/positive bacteria). Original library can be expanded and shared ■ Identification of one sample in 1 minute, 96 samples in about 40 minutes using the cell smear method (standard case) ■ Samples: general bacteria (Gram-negative/positive bacteria), yeast, mold, etc. ■ Established protocols for filamentous fungi and acid-fast bacteria ■ Certified by AOAC OMA (official method) ■ Audit-compliant software (21 CFR Part 11 support) ■ Manufacturer's warranty for 7 years or 500 million shots of the measuring laser, whichever comes first ■ Identification of difficult-to-identify bacteria in lipids using negative ion mode (Negative ion mode is only available on Sirius) ■ Equipment used: Microbial rapid identification MALDI Biotyper Sirius / Sirius One

• Analytical Equipment and Devices

■ Low cost per sample, around several dozen yen ■ General bacteria (Gram-negative/positive bacteria), 4274 species. Original library can be expanded and shared ■ Identification of one sample in 1 minute and 96 samples in about 40 minutes using the cell smear method (standard case) ■ Samples: General bacteria (Gram-negative/positive bacteria), yeast, mold, etc. ■ Established protocols for filamentous fungi and acid-fast bacteria ■ Certified by AOAC OMA (official method) ■ Manufacturer's warranty for 7 years or 500 million shots, whichever comes first, for the measurement laser ■ Identification of difficult-to-identify bacteria in lipids using negative ion mode (Negative ion mode is only available on Sirius) ■ Equipment used: Microbial rapid identification MALDI Biotyper Sirius / Sirius One

• Analytical Equipment and Devices

This document explains how to save time with rapid and easy microbial strain typing using the IR BioTyper at Technosuruga Lab (Shizuoka Prefecture). The IR BioTyper has the significant advantage of not being limited to specific types of microorganisms, allowing for the identification of a wide variety of microbial strains. Images and diagrams are included for a detailed explanation. We encourage you to read it. 【Contents】 - Saving time with rapid and easy microbial strain typing using the IR BioTyper - Advanced infrared spectroscopy - Looking towards the future *For more details, please refer to the PDF document or feel free to contact us. *This product is for research purposes only and cannot be used for clinical diagnostic purposes.

• Other physicochemical equipment

This document explains the birth of MALDI-TOF MS, the development of the MALDI Biotyper, and the expansion of its applications. It reflects on the history of MALDI-TOF MS, the early role of scientists at Bruker in the manufacturing of commercial MALDI-TOF MS systems, and the impact of the widespread adoption of this technology. We encourage you to read it. 【Contents (partial)】 ■ Introduction ■ The birth of MALDI and the history of its early days ■ Bruker's first commercial MALDI-TOF MS system ■ Early applications of MALDI-TOF MS ■ Improvements in the usability of MALDI-TOF MS systems *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

To facilitate the difficult identification of filamentous fungi such as molds and multicellular fungi, we have developed a cultivation method for creating reference spectra for the MALDI Biotyper (MBT) filamentous fungi library and a standard three-step workflow for identification. This catalog includes analyses that can be measured directly from agar media and the three-step identification workflow for filamentous fungi. We invite you to read it. 【Contents (partial)】 ■ Tackling the issues of MALDI Biotyper filamentous fungi ■ Workflow for routine testing: analyses that can be measured directly from agar media ■ Three-step identification workflow to complement the diversity of filamentous fungi ■ Beyond just a library ■ MBT Filamentous Fungi Library *For more details, please refer to the PDF materials or feel free to contact us. *This product is for research use only and cannot be used for clinical diagnostic purposes.

• Other physicochemical equipment

The MBT STAR-BL software module, when used in conjunction with the MBT STAR-Carba and MBT STAR-Cepha kits, enables reliable, rapid, and cost-effective analysis of β-lactamase activity in bacteria. [Contents (partial)] ■ MBT STAR-BL Assay - Simple Workflow ■ MBT STAR-Cepha Kit ■ MBT STAR-Carba Kit ■ Analysis of MBT STAR-BL - Convenient Kit *For more details, please refer to the PDF materials or feel free to contact us. *This product is for research use only and cannot be used for clinical diagnostic purposes.

• Analytical Equipment and Devices

The MBT subtyping module enables the differentiation of important closely related species and the automatic detection of specific drug resistances, all achievable in a single workflow thanks to the excellent identification capability of the MALDI-TOF mass spectrometer. Examples: Detection of KPC-producing Klebsiella pneumoniae Subtyping of MRSA Subtyping of Bacteroides fragilis cfiA Differentiation of Mycobacterium chimaera and M. intracellulare Identification of Listeria monocytogenes *For more details, please refer to the PDF document or feel free to contact us. *This product is for research use only and cannot be used for clinical diagnostic purposes.

• Analytical Equipment and Devices

The "MALDI Biotyper Mycobacteria Library" provides a comprehensive solution for laboratories that require higher reliability and rapid identification of mycobacteria through MALDI-TOF mass spectrometry. The Mycobacteria Library 7.0 includes 182 species. Out of 1069 strains, 584 are clinical isolates, covering the diversity of mycobacteria in nature. Furthermore, by applying the MBT Mycobacteria software module to the acquired and analyzed data, highly sensitive identification of mycobacteria can be performed. 【Features】 ■ MycoEX protocol for suitable and safe extraction ■ Same workflow for solid media and liquid media ■ Improved strain coverage by the International Mycobacteria Consortium ■ Suitable mycobacteria identification *For more details, please refer to the PDF document or feel free to contact us. *This product is for research use only and cannot be used for clinical diagnostic purposes.

• Other physicochemical equipment

The "MBT Biotarget 96" is a disposable target plate specifically designed for the MALDI Biotyper. It allows the use of all 96 spots without wasting any unused spots. Additionally, each plate comes with a unique barcode to support traceability. The hydrophilic sample application area is surrounded by a hydrophobic surface treatment, which allows liquids to concentrate on the spots, enabling the application of reagents in a clean circular shape. By eliminating the need for cleaning, it reduces working time and enhances the reliability of analytical results by preventing contamination. It has gained support from the perspective of laboratory management and has built a solid track record. 【Features】 ■ No cleaning required ■ Prevention of contamination due to insufficient cleaning ■ Suppression of sample leakage from spots ■ Efficient use of all 96 spots without waste *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

The IR Biotyper is a rapid and simple strain typing device that utilizes Fourier Transform Infrared (FT-IR) spectroscopy systems. Regular strain typing of collected microbial isolates allows for proper monitoring of microbial contamination and facilitates proactive root cause analysis and corrective actions for cleaning process management. 【Features】 ■ Low cost of approximately 400 yen per sample ■ Applicable to various microbial species (general bacteria, yeasts, etc.) ■ Results can be analyzed within 3 hours with simple techniques (standard case) ■ Capable of distinguishing between strains of the same species ■ Flexible selection of analysis areas ■ Typing analysis such as serotyping is possible with the learning function of artificial intelligence ■ New analysis methods can be created using the differential display function of analysis areas ■ Equipment used: Microbial strain typing system IR Biotyper *For more details, please refer to the PDF document or feel free to contact us.

• Analytical Equipment and Devices