Solving the Mystery of Neurons: A new application report introduces an assay method that correlates ion channel currents with the excitability of dementia neurons derived from hiPSCs.

An assay method that correlates ion channel currents with neuronal excitability in hiPSC-derived dementia neurons is introduced.

Human induced pluripotent stem cells (hiPSCs) are a highly versatile platform for modeling human neurons, enabling the generation of excitatory neurons for in vitro models. To understand the electrophysiological properties of neurons, such as excitability and synaptic transmission, recording ion channels in hiPSC-derived neurons is key. Researchers can investigate healthy neurophysiological functions by capturing the dynamics of ion channel currents, such as sodium, potassium, and calcium, as well as explore dysfunctions related to neurological disorders like epilepsy, autism, and neurodegenerative diseases. These models provide valuable tools for studying disease mechanisms and testing potential therapeutic interventions in patient-specific contexts. *For more details, please refer to the related links. Feel free to contact us for more information.*

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Do you have any concerns or requests regarding wired bed exit sensors? × Tangling and tripping of wired cables × Cable disconnection or damage × Worry about forgetting to turn on the switch after temporarily stopping the sensor. × Want to be notified of bed exit even from a location away from the nurse call outlet. Such concerns can be resolved simply by connecting to a wireless set linked to the nurse call system! Our nurse call linked wireless set allows you to connect bed exit sensors like "Ugo-kun," "Foldable Thin Matta-kun," "Ayumi-chan," and "Just Place Pole-kun" to transmitters and receivers, reducing wiring around the bed, alleviating concerns about tripping and falling due to cables, and contributing to a tidier work environment. Furthermore, it enables the use of bed exit sensors even from locations away from the nurse call outlet, allowing for more flexible equipment placement.

● This is a leak testing device for small electronic components that does not use fluorinated inert liquids (PFAS-free). ● There is no longer a need for unstable visual confirmation through liquid immersion testing. It adopts a quantitative testing method that allows for stable pressure leak testing. ● It is a tabletop leak testing device specifically for gross leaks, with accuracy equal to or greater than that of liquid immersion testing. ● The detectable range is approximately 1×10⁻² Pa·m³/s to 1×10⁻⁶ Pa·m³/s (varies depending on the target product). ● It is suitable for sealed structures ranging from a few millimeters to a maximum of 80 × 70 mm. Please feel free to contact us for more information!

Hotron's vehicle detection sensors allow you to search for products that meet your needs in three categories: "Purpose of Use," "Location of Use," and "Product List." The sensors detect the passage of vehicles, alerting you with rotating lights or switching the display of parking availability. They manage vehicle presence, full parking, and exit warnings in parking lots, contributing to safe driving and smooth operational management within the parking area. They are used in various settings, from coin-operated parking to large-scale parking lots.

The "Mechanical Stitching Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed, and repairs are made without causing any thermal impact to the base material. Repairs can be carried out even in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.

The RNP-45 is a surface mount power film resistor designed to be compatible with the TO-252 package, weighing only 0.33 grams, with a thermal resistance of 3.0°C/W and a rated power of 45W. The resistive element is a pulse-resistant thick film, featuring excellent high-frequency characteristics with a reactance component of 2.7pF and 14.7nH, while also having a pulse power performance of 1kW-1µs despite its small size. The operating temperature range is from -55 °C to +175 °C. Additionally, it incorporates several design features, such as the removal of the metal flange to maximize the thermal performance of the resistor, compatibility with standard reflow SAC solder joints instead of wire bond connections, making it suitable for automatic mounting, an increased resistive element area to enhance surge performance, and the adoption of a 0.8mm substrate to strengthen bending stress.