[On-Demand Streaming Available] International Webinar "2nd Process Enhancement Webinar Series News and Seminar Information"

Process enhancement. Modify. Intensify. Amplify.

Process Intensification (PI) is a comprehensive framework aimed at maximizing overall production volume across manufacturing units, manufacturing processes, or biopharmaceutical facilities. Sartorius Stedim offers scalable and versatile modular solutions, including high-throughput process development tools. These can be implemented in current and future manufacturing facilities for a variety of upstream and downstream PI scenarios. - Enables faster drug development - Improves efficiency and productivity in GMP manufacturing - Applicable to various processes regardless of the pharmaceutical ◆ International Webinar [Process Intensification Webinar Series] This webinar series provides a comprehensive guide to maximizing process intensification. It covers upstream and downstream strategies, media management, data analysis, and more. You can watch it here: ⇒ https://bit.ly/3ihwdT1

• Other physicochemical equipment

Introducing a medium system for protein production using the CHO system!

The starter kit for the culture system "4Cell XtraCHO" includes all the necessary culture components for cell acclimatization and fed-batch culture at a 3L capacity. When progressing to larger-scale cultures, all individual culture components are available in various forms, both liquid and powder. Using production media and feed media offers benefits such as "eliminating process variability and contamination risks." 【Customer Benefits】 ■ Production Efficiency: Ideal efficiency from bench scale to manufacturing scale ■ Compliance with Regulatory Guidelines: Eliminates process variability and contamination risks ■ Reduces Process Complexity: Facilitates purification *For more details, please refer to the PDF materials or feel free to contact us.

• others

A single-use benchtop bioreactor with simple operation aimed at improving productivity.

The industry-standard multi-channel, compact fully automated bioreactor, Ambr250 in a benchtop configuration, has arrived with new features and applications for regenerative medicine. It allows for independent cultivation with highly controlled single-use containers with operating capacities of 100-250 mL, arranged in a maximum of 8 channels. There are three types of containers, each specialized for cells, microorganisms, and regenerative medicine, with a refined design that contributes to process development and optimization. Since the containers are single-use and sterilized, they enable fast turnover, accelerating customers' research and development activities. Because it is geometrically identical to bioreactors used for production scale in pharmaceuticals and regenerative medicine products, it is possible to quickly transition and implement optimized cultivation and production conditions.

• Other physicochemical equipment

A fully automated bioreactor system for the development of high-density cell culture processes!

The "Ambr250 Perfusion" is a fully automated multi-parallel bioreactor system that uses single-use culture vessels of 100-250 mL to accelerate the development of scalable perfusion processes. This system allows for the simultaneous execution of up to 24 different perfusion cultures while returning cells to the culture vessel using hollow fibers, which are commonly reported specifications. This system transforms the perfusion processes that could not be achieved with multi-parallel or small-scale setups, reducing experimental costs with small volumes and accelerating the optimization of high-density cell culture processes. 【Features】 ■ Increased productivity / Reduced experimental costs ■ Simultaneous parallel fed-batch and perfusion cultures are also possible ■ Exceptional scalability ■ Sampling and reagent addition are performed by a fully automated liquid handler, reducing daily working hours *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

A new bioreactor system for parallel operation of microbial culture or cell culture!

The "Ambr250" is a new bioreactor system for parallel operations of microbial or cell cultures using single-use bioreactors with a capacity of 100 to 250 mL, controlled by an automated liquid handling platform. This system was developed in collaboration with two major pharmaceutical companies, based on the micro bioreactor technology held by Sartorius Stedim's TAP division. It supports the necessary culture conditions required for microbial cultivation and mammalian cell culture, which demand advanced technology, as well as applications that require larger sample collections. 【Features】 ■ Individual control of all process parameters ■ Improved operating environment ■ Efficient and rapid miniaturization system ■ Equipped for scalability to benchtop bioreactors ■ Capable of screening a wide range of culture conditions and strains or cell lines *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

Enhancing equipment performance that influences the success of cultivation! We have achieved improved flexibility.

The "Ambr15 Generation2" is a high-throughput automated micro-scale bioreactor system that replicates the performance of laboratory-scale bioreactors. The system consists of single-use vessels, an automated workstation, and user-friendly software. It is designed to be installed in standard biosafety cabinets for aseptic operations, allowing for parallel monitoring and control of 24 or 48 micro-bioreactor cultures. 【Features】 ■ Reduces operator time and increases work efficiency ■ Facilitates the process of determining the best clone ■ Enables faster and more accurate operations ■ Capable of complex liquid mixing and addition for multifactorial experimental designs (DoE) ■ Used in research facilities worldwide *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

Bioreactor system for cell line development and process optimization.

The Ambr1515 Generation 2 is a high-throughput "automated micro-scale bioreactor system" that reproduces the performance of laboratory-scale bioreactors. The system consists of single-use vessels, an automated workstation, and enhanced convenience software. It is designed to be installed in a standard biosafety cabinet for aseptic operations, allowing for parallel monitoring and control of 24 or 48 micro-bioreactor cultures. As the manufacturing processes for biopharmaceuticals become more complex and the density of cultures increases, scientists around the world are facing an unprecedented challenge in developing "clone, medium, and process" that meet new demands. The Ambr15 Generation 2 system enhances equipment performance that influences the success of cultures, improves flexibility, and incorporates new features that reflect user feedback. It helps address the aforementioned challenges and supports the acceleration of research by scientists.

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A multi-talented benchtop bioreactor that supports the research and development of biopharmaceuticals.

"Biostat B" is a benchtop bioreactor equipped with a control tower that possesses multi-talented capabilities to meet the diverse and varied needs of our customers. It offers a multitude of possibilities by combining three types of culture vessels with proven performance in single and twin configurations. With thousands of units delivered in over 50 countries worldwide, our extensive experience and collaboration with customers globally support this track record. [Features] ■ A bioreactor with proven performance worldwide ■ Custom-made devices can be produced to meet customer specifications using our unique design system ■ Established high quality *For more details, please refer to the PDF document or feel free to contact us.

• others

A single-use bioreactor system that dramatically enhances speed, quality, and productivity from process development to scale-up.

The "Biostat STR Series" is a single-use bioreactor system designed for rapid process development and seamless scale-up to commercial production. The newly launched third generation features a new automation platform, "BIOBRAIN," and the analytical tool "BioPAT(R)," enabling exceptional speed, quality, and productivity. Stable and predictable processes greatly contribute to providing safe and reliable biopharmaceuticals to patients worldwide, accelerating our customers' manufacturing operations and business.

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[Instructor] Shintaro Fukasawa, President of BM Consulting Co., Ltd. Business Mathematics Educator [Key Lecture Content] There are things we somewhat think about. However, when asked for our opinions, we hesitate to speak up because we dread being questioned with "What is your basis?" This is a growing issue among business professionals. Shintaro Fukasawa, the only advocate of business mathematics in Japan and a business mathematics educator, identifies the inability of modern business people to articulate their thoughts and ideas as a "symptom." He finds commonalities between mathematical thinking and verbalization, and has developed a verbalization framework that anyone can easily practice. This content has been compiled into a book titled "How Can an Idea Become 'My Opinion'? - A Class to Turn Intuition into Logical Opinions" (2023). In this session, we will extract the essence of that book and explain how to create "logical and communicative opinions." You will take home tips that will dramatically change your business communication starting tomorrow.

[Speaker] Tokyo Electric Power Company Holdings, Inc. Area Energy Innovation Business Office Battery Business Group Manager Akira Oguri [Key Lecture Content] In a carbon-neutral society where renewable energy becomes the main power source, batteries play a crucial role in avoiding output suppression of renewable energy and providing adjustment capabilities to the power grid. Utilizing the knowledge, business experience, and engineering skills cultivated through NAS batteries and the electric power business, we will introduce our efforts to provide battery energy services that align with the actual usage of customers aiming for carbon neutrality and resilience enhancement. [Lecture Items] 1. Tokyo Electric Power Group's initiatives toward carbon neutrality 2. Current situation surrounding the battery market 3. Safety requirements for battery systems 4. Introduction of Tokyo Electric Power Group's initiatives related to batteries 5. Future business outlook 6. Q&A / Business card exchange

[Speaker] Takuya Oue, Executive Officer COO, ExaWizards Inc. Hiroaki Izuma, Advisor, Business Creation Division, Tohoku Electric Power Co., Inc. Advisor, ExaWizards Inc. [Key Lecture Content] Since the emergence of ChatGPT at the end of 2022, generative AI has rapidly permeated various aspects of society, fundamentally changing its nature. In Japan's energy industry, which is faced with the extremely challenging task of simultaneously addressing the supreme issues of decarbonization, stable supply, and economic growth, AX (AI Transformation) based on the utilization of AI plays a crucial role. This lecture will illustrate the AX in the energy sector and depict the vision for 2030 based on a wealth of examples. [Lecture Topics] 1. Structural transformation facing the energy industry 2. Energy AX from the field perspective 3. Learning from the AX strategies of major domestic players 4. Learning from advanced overseas examples 5. Vision for 2030 6. Q&A / Business card exchange

Thank you very much for your continued support. We are pleased to announce the 2024 Cutting Heat Treatment Research Conference, which will be held as follows. This year, it will be conducted online via ZOOM. <Date and Time> February 13, 2025 (Friday) Event Time: 10:00 AM - 5:00 PM (Login starts at 9:30 AM) Cutting Part: 10:00 AM - DX & Environment: 1:00 PM - Heat Treatment Part: 3:00 PM - <Registration Method> This event will be conducted by prior reservation. Participation Fee: Free Registration Deadline: February 6, 2026 (Friday) *Please check the details at the provided URL. We look forward to your participation. Thank you very much for your cooperation. ◆ Seminar Information URL https://www.idemitsu.com/jp/business/lube/news/2025/251212.pdf

We will be exhibiting at "Japan IT Week Nagoya," which will be held at Port Messe Nagoya from February 25 (Wednesday) to February 27 (Friday), 2026. Japan IT Week Nagoya is the largest comprehensive exhibition in the Chubu region related to system development, operation, and maintenance. It consists of four exhibitions. Our company will be participating in the "Embedded, Edge, and IoT Development EXPO." At our booth, we will offer free consultations on our production management cloud system, "SmartF." If you have any of the following concerns, please feel free to stop by our booth: ✅ I want to know how to digitalize the manufacturing site. ✅ I am considering implementing barcode management. ✅ I want to move away from manual management using handwritten notes or Excel. ✅ I want to streamline the management of inventory, quality, and costs. ✅ I want to know the differences from the production management system I am currently using. We can also provide proposals based on the challenges faced by attendees. If you have any issues with digitalizing your operations, please feel free to consult with us!