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  6. Process Intensification

Process Intensification

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last updated:Nov 06, 2025

Sartorius Stedim Japan K.K.
Sartorius Stedim Japan K.K.
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Process enhancement. Modify. Intensify. Amplify.

Process Intensification (PI) is a comprehensive framework aimed at maximizing overall production volume across manufacturing units, manufacturing processes, or biopharmaceutical facilities. Sartorius Stedim offers scalable and versatile modular solutions, including high-throughput process development tools. These can be implemented in current and future manufacturing facilities for a variety of upstream and downstream PI scenarios. - Enables faster drug development - Improves efficiency and productivity in GMP manufacturing - Applicable to various processes regardless of the pharmaceutical ◆ International Webinar [Process Intensification Webinar Series] This webinar series provides a comprehensive guide to maximizing process intensification. It covers upstream and downstream strategies, media management, data analysis, and more. You can watch it here: ⇒ https://bit.ly/3ihwdT1

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Process Intensification

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TEI-Intro-Blog-Post-Visual-B-0001265-Sartorius.jpg The key PI products across the complete PD and manufacturing process.png PI.PNG
  • Process Intensification
  • Special site - Product/service details - https://pr.mono.ipros.com/sartorius-stedim/product…

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basic information

Biopharmaceutical manufacturers and CDMOs are facing the challenge of improving throughput and reducing costs to maintain competitiveness, making PI seem like a natural solution. However, the reality is that implementing the level changes that many expect is difficult. Sartorius Stedim will enhance key processes to help manufacturers align current demand with future developments, allowing them to experience the current benefits of PI while building for the future.

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Applications/Examples of results

Key PI products across PD and the entire manufacturing process: Biostat RM and Flexsafe RM Biostat STR Generation 3 and Biobrain Automation Platform CellcaCHO Expression Platform Ambr 15 Cell Culture System Ambr 250 for perfusion-enabled processes 4Cell XtraCHO-Media System Integrated, scalable PAT Solutions With a comprehensive PD portfolio, customers can submit Investigational New Drug (IND) applications more quickly.

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[Report] Process Improvement (PI) Research: Insights from Experts

[Report] Process Improvement (PI) Research: Insights from Experts

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Biostat STR Generation 3 (Commercial Production Model)

Biostat STR Generation 3 (Commercial Production Model)

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BIOSTAT STR Generation 3 Bioreactor and Flexsafe STR Bag

BIOSTAT STR Generation 3 Bioreactor and Flexsafe STR Bag

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Biostat RM and FlexSafe RM

Biostat RM and FlexSafe RM

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Ambr15 Cell Culture System Generation 2 Catalog

Ambr15 Cell Culture System Generation 2 Catalog

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Ambr250 High-Throughput Perfusion

Ambr250 High-Throughput Perfusion

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4Cell XtraCHO Medium System Product Data Sheet

4Cell XtraCHO Medium System Product Data Sheet

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Ambr 15 Cell Culture References

Ambr 15 Cell Culture References

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Sending recorded video: What are the equipment requirements needed for the process enhancement challenge?

  • Seminar・Event

Participation in this webinar has ended. If you wish to view it, please contact us, and we will send you the URL for the recorded video at a later date. Since last year, Sartorius has been presenting various proposals and suitable solutions for the challenges of "enhancing processes." In this first webinar of 2022, we will delve deeper than last year's trilogy and discuss several examples regarding cost and equipment considerations. The focus will particularly be on how to manage media that significantly impacts costs and how to design equipment. Please note that this webinar will be presented as the Japanese version of the overseas webinar "Overcoming Facility Constraints Posed by Process Intensification." ▪ Method of holding: Webinar recorded broadcast [Japanese, Free]

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[Sending recorded video] 11/2 [Every Tuesday in Japan] Process Enhancement Series, all 3 sessions - Session 2: High-Throughput Bioreactor Supporting Process Enhancement Efforts

  • Seminar・Event

Participation in this webinar has ended. If you wish to view it, please contact us, and we will send you the URL for the recorded video at a later date. The success or failure of the cultivation process significantly contributes to subsequent productivity, quality, and yield, even within the overall enhanced process. Therefore, the role of process development and optimization for cultivation is positioned as extremely important, and it is necessary to implement these approaches in conjunction with production bioreactors. As the number of considerations increases, there is a demand for cost and labor reduction, and our Amber System is the solution to achieve this. Since 2020, our model capable of perfusion cultivation has received positive feedback, and in the second installment, we will thoroughly convey this feature and its advantages. [Learnable Elements] - Evolved approaches to process development - Advantages of parallel implementation in multi-channel setups [Method of Hosting] Webinar recorded broadcast [Japanese, Free] *Special novelty items will be sent from our company to those who participated in all sessions from the first to the third on the same day.

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[Sending Recorded Video] 10/26 [Every Tuesday in Japan] Process Enhancement Series, All 3 Sessions - Session 1: Approaches to Strengthening Biopharmaceutical Manufacturing Processes

  • Seminar・Event

Participation in this webinar has ended. If you wish to view it, please contact us, and we will send you the URL for the recorded video at a later date. In recent years, the manufacturing processes of biopharmaceuticals have been shifting from large-scale equipment structures to enhancing individual processes to increase overall production volume. The core technology continues to heavily utilize single-use systems, and various approaches are available in both upstream and downstream processes to meet the goals of drug manufacturing. We will convey how to enhance your individual processes, including approaches, solutions, and ideal states, and will delve into specific topics in subsequent sessions. [Learnable Elements] - Approaches to process enhancement - Single-use bag bioreactors - Continuous chromatography technology [Method of Delivery] Recorded broadcast [in Japanese, free of charge] *Novelty items will be sent from our company to those who participated continuously from the first to the third session on the same day.

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[On-Demand Streaming Available] 9/30 (Thursday) International Webinar "Strengthening Upstream Processes and Overcoming Challenges in Commercial Production"

  • Seminar・Event

Registration for this webinar has ended. Those who wish to view it on demand can register through the details and application section. In this webinar, we will explain the main features of the Amber system that correspond to various stages of clone selection under perfusion mimic conditions and complete perfusion conditions, as well as media and feed screening, and optimization of process parameters in small-scale bioreactors. [Topics] - Introduction of high-throughput capabilities for upstream intensification in various modes of Amber: perfusion mimic, ATF, TFF - Amber user case studies: showcasing performance in high-throughput enhanced process development - Discussion of a modular concept for enhanced seed trains utilizing perfusion and decision-making based on specific needs - Evaluation of time and cost advantages of modular seed trains based on predetermined process types Even if you cannot attend the live webinar, a link to the on-demand archive will be sent to those who registered.

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Sartorius

Sartorius Stedim Japan K.K.

Pharmaceuticals and Biotechnology

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Sartorius Stedim, established in 2007 through the merger of the German company Sartorius, founded in 1870, and the French company Stedim, is a pioneer in "Single-Use Technology (SUT)." As a company capable of providing comprehensive technical support to the pharmaceutical and biotechnology industries, its cutting-edge technology is highly regarded worldwide in the fields of scientific instruments and biotechnology.

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