[Sending Recorded Video] 10/26 [Every Tuesday in Japan] Process Enhancement Series, All 3 Sessions - Session 1: Approaches to Strengthening Biopharmaceutical Manufacturing Processes

Process enhancement. Modify. Intensify. Amplify.

Process Intensification (PI) is a comprehensive framework aimed at maximizing overall production volume across manufacturing units, manufacturing processes, or biopharmaceutical facilities. Sartorius Stedim offers scalable and versatile modular solutions, including high-throughput process development tools. These can be implemented in current and future manufacturing facilities for a variety of upstream and downstream PI scenarios. - Enables faster drug development - Improves efficiency and productivity in GMP manufacturing - Applicable to various processes regardless of the pharmaceutical ◆ International Webinar [Process Intensification Webinar Series] This webinar series provides a comprehensive guide to maximizing process intensification. It covers upstream and downstream strategies, media management, data analysis, and more. You can watch it here: ⇒ https://bit.ly/3ihwdT1

• Other physicochemical equipment

Industry-standard high-throughput bioreactor system optimized for process characteristic analysis.

The Ambr 250 High Throughput Generation 2 is a multi-parallel bioreactor system that accelerates process development and characterization analysis schedules to achieve cost reduction. Its fully continuous gas supply system realizes similarity with large-scale bioreactors and optimizes the scale-down model. Through the integration of analysis options such as the capacitance-based BioPAT Viamass, it supports extensive feedback control.

• others
• Culture Equipment
• Bioreactor

Bioreactor system for cell line development and process optimization.

The Ambr1515 Generation 2 is a high-throughput "automated micro-scale bioreactor system" that reproduces the performance of laboratory-scale bioreactors. The system consists of single-use vessels, an automated workstation, and enhanced convenience software. It is designed to be installed in a standard biosafety cabinet for aseptic operations, allowing for parallel monitoring and control of 24 or 48 micro-bioreactor cultures. As the manufacturing processes for biopharmaceuticals become more complex and the density of cultures increases, scientists around the world are facing an unprecedented challenge in developing "clone, medium, and process" that meet new demands. The Ambr15 Generation 2 system enhances equipment performance that influences the success of cultures, improves flexibility, and incorporates new features that reflect user feedback. It helps address the aforementioned challenges and supports the acceleration of research by scientists.

• others

A fully automated bioreactor system for the development of high-density cell culture processes!

The "Ambr250 Perfusion" is a fully automated multi-parallel bioreactor system that uses single-use culture vessels of 100-250 mL to accelerate the development of scalable perfusion processes. This system allows for the simultaneous execution of up to 24 different perfusion cultures while returning cells to the culture vessel using hollow fibers, which are commonly reported specifications. This system transforms the perfusion processes that could not be achieved with multi-parallel or small-scale setups, reducing experimental costs with small volumes and accelerating the optimization of high-density cell culture processes. 【Features】 ■ Increased productivity / Reduced experimental costs ■ Simultaneous parallel fed-batch and perfusion cultures are also possible ■ Exceptional scalability ■ Sampling and reagent addition are performed by a fully automated liquid handler, reducing daily working hours *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

A fully automated tool for acquiring and fully utilizing Raman spectroscopy data to build a robust cultivation process for the production of uniform and high-quality products.

BioPAT(R) Spectro is a product specifically developed for Quality by Design (QbD). By generating more process data using this product, the potential of Raman spectroscopy can be maximized. This enables the construction of very robust processes, resulting in the production of consistently high-quality products.

• others

A single-use bioreactor system that dramatically enhances speed, quality, and productivity from process development to scale-up.

The "Biostat STR Series" is a single-use bioreactor system designed for rapid process development and seamless scale-up to commercial production. The newly launched third generation features a new automation platform, "BIOBRAIN," and the analytical tool "BioPAT(R)," enabling exceptional speed, quality, and productivity. Stable and predictable processes greatly contribute to providing safe and reliable biopharmaceuticals to patients worldwide, accelerating our customers' manufacturing operations and business.

• others

Seed culture for small-scale protein production.

- The BioStat RM is a single-use rocking bioreactor that is fully compliant with GMP. < BioStat RM 20 | 50 Basic > The BioStat RM 20 | 50 Basic is a standalone bioreactor that is the ideal size for benchtop use. < BioStat RM 200 > The BioStat B and RM 200 Rocker are single-use rocking bioreactors designed for large-scale applications. - The Flexsafe bags have a proven track record with a wide range of cell lines including CHO, NS0, SF9, E. coli, T cells, and mesenchymal stem cells. Using Flexsafe RM bags in the seed train allows for easy scale-up to the BioStat STR single-use bioreactor that utilizes Flexsafe STR bags. The same polyethylene film material can be used for all cell culture steps. Flexsafe RM bags can be used with rocking bioreactors from multiple manufacturers, providing excellent growth characteristics and robustness, with stable supply.

• others

At Eihon Seiki, we handle Brookfield's rotational viscometers, which are widely used by many customers. We offer consulting services such as measurement method proposals and data analysis to assist our customers with viscometers and rheometers. As part of our ongoing commitment to customer service, we have planned a viscometer user seminar. We will invite Professor Toshiyuki Shikata, an emeritus professor at Tokyo University of Agriculture and Technology, who is active in the field of rheology, to give a lecture covering the basics of viscosity and an introduction to viscoelasticity. There will also be opportunities to ask questions to Professor Shikata and our technical staff regarding any issues or uncertainties you may have in your daily work. We encourage you to consider participating in this opportunity. Seminar Overview: - We will provide an easy-to-understand lecture on the basics of viscosity and viscosity measurement. - We will explain points that can help improve the reproducibility of daily measurements and maintenance within your company. - We will introduce the dispersion of solutions and stability evaluation through live demonstrations. - You will have the opportunity to ask questions directly to Professor Shikata and Eihon Seiki's technical staff.

[Key Lecture Content] 1. The current status of geothermal heat in our country and the Ministry of the Environment's initiatives for its promotion Ministry of the Environment, Water and Air Quality Bureau, Environmental Management Division, Environmental Pollution Control Office Assistant Director Matsui Tatsu 1. About geothermal heat 2. About groundwater heat 3. Utilization for energy conservation 4. Utilization for decarbonization 5. Q&A / Business card exchange 2. Technological trends of geothermal heat pumps and advanced examples from Japan and abroad Non-profit organization Geothermal Utilization Promotion Association Chairman Sasada Masakatsu 1. Overview of geothermal heat pumps and their energy-saving and environmental properties 2. Trends in closed-loop technology 3. Trends in open-loop technology 4. Technological trends of air conditioning systems using geothermal heat as a heat source 5. Future prospects for geothermal heat pumps 6. Q&A / Business card exchange

[Speaker] Cabinet Office, Government of Japan Science and Technology Innovation Promotion Office Planning Officer Takayuki Sato [Key Lecture Content] Japan's AI policy is structured around the fundamental directions of "balancing innovation promotion and risk response" and "international cooperation." In the AI Basic Plan established at the end of last year, we aim to pursue "trustworthy AI" that maintains a human-centered AI society where individual dignity is respected, enabling continuous collaboration between humans and AI. Our goal is to make Japan "the easiest country in the world to develop and utilize AI." This lecture will provide an overview of Japan's AI policies, including examples of initiatives. [Lecture Items] 1. Evolution and development trends of AI 2. Japan's AI policy (background of the AI law enactment, promotion system, etc.) 3. AI-related initiatives (AI Basic Plan, AI guidelines, etc.) 4. Q&A / Business card exchange

In this 5S seminar, we won't just stop at "organizing and tidying up." We will provide plenty of tips on how to utilize 5S as a "visualization of work" and a "tool for discovering waste," evolving the workplace into a more comfortable and productive environment! ✅ Improvement tips you can use starting tomorrow ✅ Engaging and practical exercises and workshops that will inspire and excite you From "doing it because I was told to" to "wanting to take action myself" Your step forward will lead to the evolution of the entire team. This is an opportunity to cultivate a "mindset for improvement" among young employees and enhance the autonomy of the entire organization. From "waiting for instructions" to "thinking and taking action" As you become more accustomed to your work, you will notice the waste and potential that exists. Now, let's gain the "power to change" with 5S! Benefits of 5S: 1. People grow 2. Time becomes more abundant 3. The workplace environment improves 4. 5S does not require significant costs 5. It can be implemented regardless of company size or job type 6. It is appreciated by stakeholders We will teach you the tips to transform 5S from something done because a superior said to do it, or only when there is time, into an enjoyable and sustainable practice. *For more details, please download the PDF or contact us.

This exhibition is one of the largest specialized symposiums in Japan, focusing on fullerenes, carbon nanotubes (CNT), graphene, nanomaterials, advanced materials, functional materials, and two-dimensional materials. Many researchers and engineers involved in material development, device applications, measurement and analysis, research and development, and mass production technology will attend. At our booth, we will introduce products and technological solutions that support research in nanocarbon, advanced material evaluation, device development, and industrial applications from fundamental research. ■ Planned Exhibits - Products from PicoQuant - Ultra-high stability interferometer "GEMINI" (NIREOS) - Superconducting nanowire single-photon detector (SNSPD) (Single Quantum) - Broadband wavelength-tunable laser 400–1000nm SuperK CHROMATUNE (NKT Photonics)