Seed culture for small-scale protein production.
- The BioStat RM is a single-use rocking bioreactor that is fully compliant with GMP. < BioStat RM 20 | 50 Basic > The BioStat RM 20 | 50 Basic is a standalone bioreactor that is the ideal size for benchtop use. < BioStat RM 200 > The BioStat B and RM 200 Rocker are single-use rocking bioreactors designed for large-scale applications. - The Flexsafe bags have a proven track record with a wide range of cell lines including CHO, NS0, SF9, E. coli, T cells, and mesenchymal stem cells. Using Flexsafe RM bags in the seed train allows for easy scale-up to the BioStat STR single-use bioreactor that utilizes Flexsafe STR bags. The same polyethylene film material can be used for all cell culture steps. Flexsafe RM bags can be used with rocking bioreactors from multiple manufacturers, providing excellent growth characteristics and robustness, with stable supply.
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<Process> – Production of proteins and cells for preclinical purposes – Seed culture for large bioreactors – GMP production <Cell> – Mammalian, insect, and plant cells – Suspended and adherent cells on microcarriers – Low to medium density microbial cultures – Shear-sensitive cells (stem cells or T cells) <Purpose> – Scale-up from shaker or T-flask – Rapid production of samples for preclinical trials – Proliferation and differentiation of stem cells – Production of recombinant proteins, mAbs, and vaccines – Continuous culture at a cell density of 1.5 × 10^8 cells/mL <Capacity> – Culture volumes from 100 mL to 100 L – Two body sizes: 20/50 and 200
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Sartorius Stedim, established in 2007 through the merger of the German company Sartorius, founded in 1870, and the French company Stedim, is a pioneer in "Single-Use Technology (SUT)." As a company capable of providing comprehensive technical support to the pharmaceutical and biotechnology industries, its cutting-edge technology is highly regarded worldwide in the fields of scientific instruments and biotechnology.