[Sending recorded video] Cutting-edge pDNA and AAV therapeutics: Comprehensive upstream process technology covering everything from process development to actual production.

Enhancing equipment performance that influences the success of cultivation! We have achieved improved flexibility.

The "Ambr15 Generation2" is a high-throughput automated micro-scale bioreactor system that replicates the performance of laboratory-scale bioreactors. The system consists of single-use vessels, an automated workstation, and user-friendly software. It is designed to be installed in standard biosafety cabinets for aseptic operations, allowing for parallel monitoring and control of 24 or 48 micro-bioreactor cultures. 【Features】 ■ Reduces operator time and increases work efficiency ■ Facilitates the process of determining the best clone ■ Enables faster and more accurate operations ■ Capable of complex liquid mixing and addition for multifactorial experimental designs (DoE) ■ Used in research facilities worldwide *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

Introducing options and accessories that can be added to the Ambr 15 Generation 2.

You can find the following information in this catalog: ▪ System specifications ▪ Compatible at-line analyzers ▪ Expandable options ▪ Accessories ▪ Ambr 15 microbioreactor (culture vessel) ▪ Plates and chips

• Other physicochemical equipment
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Industry-standard high-throughput bioreactor system optimized for process characteristic analysis.

The Ambr 250 High Throughput Generation 2 is a multi-parallel bioreactor system that accelerates process development and characterization analysis schedules to achieve cost reduction. Its fully continuous gas supply system realizes similarity with large-scale bioreactors and optimizes the scale-down model. Through the integration of analysis options such as the capacitance-based BioPAT Viamass, it supports extensive feedback control.

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• Culture Equipment
• Bioreactor

A fully automated bioreactor system for the development of high-density cell culture processes!

The "Ambr250 Perfusion" is a fully automated multi-parallel bioreactor system that uses single-use culture vessels of 100-250 mL to accelerate the development of scalable perfusion processes. This system allows for the simultaneous execution of up to 24 different perfusion cultures while returning cells to the culture vessel using hollow fibers, which are commonly reported specifications. This system transforms the perfusion processes that could not be achieved with multi-parallel or small-scale setups, reducing experimental costs with small volumes and accelerating the optimization of high-density cell culture processes. 【Features】 ■ Increased productivity / Reduced experimental costs ■ Simultaneous parallel fed-batch and perfusion cultures are also possible ■ Exceptional scalability ■ Sampling and reagent addition are performed by a fully automated liquid handler, reducing daily working hours *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

A single-use benchtop bioreactor with simple operation aimed at improving productivity.

The industry-standard multi-channel, compact fully automated bioreactor, Ambr250 in a benchtop configuration, has arrived with new features and applications for regenerative medicine. It allows for independent cultivation with highly controlled single-use containers with operating capacities of 100-250 mL, arranged in a maximum of 8 channels. There are three types of containers, each specialized for cells, microorganisms, and regenerative medicine, with a refined design that contributes to process development and optimization. Since the containers are single-use and sterilized, they enable fast turnover, accelerating customers' research and development activities. Because it is geometrically identical to bioreactors used for production scale in pharmaceuticals and regenerative medicine products, it is possible to quickly transition and implement optimized cultivation and production conditions.

• Other physicochemical equipment

A new bioreactor system for parallel operation of microbial culture or cell culture!

The "Ambr250" is a new bioreactor system for parallel operations of microbial or cell cultures using single-use bioreactors with a capacity of 100 to 250 mL, controlled by an automated liquid handling platform. This system was developed in collaboration with two major pharmaceutical companies, based on the micro bioreactor technology held by Sartorius Stedim's TAP division. It supports the necessary culture conditions required for microbial cultivation and mammalian cell culture, which demand advanced technology, as well as applications that require larger sample collections. 【Features】 ■ Individual control of all process parameters ■ Improved operating environment ■ Efficient and rapid miniaturization system ■ Equipped for scalability to benchtop bioreactors ■ Capable of screening a wide range of culture conditions and strains or cell lines *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

New user interface

Biostat RM has been renewed with a new control tower that adopts the automation platform Biobrain, which is suitable for commercial production using a shaking-type bioreactor. 【Features】 ▪ Accelerates the market launch of customer products ▪ Simple transition from process development to commercial production ▪ Flexible specifications for diverse manufacturing needs and culture styles ▪ High-precision process control ▪ Support system by technical personnel stationed in various countries

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A single-use bioreactor system that dramatically enhances speed, quality, and productivity from process development to scale-up.

The "Biostat STR Series" is a single-use bioreactor system designed for rapid process development and seamless scale-up to commercial production. The newly launched third generation features a new automation platform, "BIOBRAIN," and the analytical tool "BioPAT(R)," enabling exceptional speed, quality, and productivity. Stable and predictable processes greatly contribute to providing safe and reliable biopharmaceuticals to patients worldwide, accelerating our customers' manufacturing operations and business.

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Seed culture for small-scale protein production.

- The BioStat RM is a single-use rocking bioreactor that is fully compliant with GMP. < BioStat RM 20 | 50 Basic > The BioStat RM 20 | 50 Basic is a standalone bioreactor that is the ideal size for benchtop use. < BioStat RM 200 > The BioStat B and RM 200 Rocker are single-use rocking bioreactors designed for large-scale applications. - The Flexsafe bags have a proven track record with a wide range of cell lines including CHO, NS0, SF9, E. coli, T cells, and mesenchymal stem cells. Using Flexsafe RM bags in the seed train allows for easy scale-up to the BioStat STR single-use bioreactor that utilizes Flexsafe STR bags. The same polyethylene film material can be used for all cell culture steps. Flexsafe RM bags can be used with rocking bioreactors from multiple manufacturers, providing excellent growth characteristics and robustness, with stable supply.

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A multi-talented benchtop bioreactor that supports the research and development of biopharmaceuticals.

"Biostat B" is a benchtop bioreactor equipped with a control tower that possesses multi-talented capabilities to meet the diverse and varied needs of our customers. It offers a multitude of possibilities by combining three types of culture vessels with proven performance in single and twin configurations. With thousands of units delivered in over 50 countries worldwide, our extensive experience and collaboration with customers globally support this track record. [Features] ■ A bioreactor with proven performance worldwide ■ Custom-made devices can be produced to meet customer specifications using our unique design system ■ Established high quality *For more details, please refer to the PDF document or feel free to contact us.

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A fully automated tool for acquiring and fully utilizing Raman spectroscopy data to build a robust cultivation process for the production of uniform and high-quality products.

BioPAT(R) Spectro is a product specifically developed for Quality by Design (QbD). By generating more process data using this product, the potential of Raman spectroscopy can be maximized. This enables the construction of very robust processes, resulting in the production of consistently high-quality products.

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We will hold a webinar on the theme "What are the appropriate methods to protect intellectual property?" This seminar will explain the key points of intellectual property document management to achieve evidential strength, tampering prevention, and operational efficiency. We will also introduce the solution "WWDS Intellectual Property Archive," which automatically clarifies the location of documents and ensures authenticity through timestamps. ■ Date and Time: December 18, 2025 (Thursday) 13:30 - 14:30 ■ Location: Online Webinar (scheduled to be held via Zoom Webinar)

[Speaker] Yoshimitsu Umabashi, Senior Researcher, Smart Resilience Network Ambassador, Research Coordination Office, Grid Innovation Research Headquarters, Central Research Institute of Electric Power Industry (Former Vice President of TN Cross Corporation) [Lecture Items] 1. What is Watt-Bit? (1) Current state of power supply capacity (2) Changes in power demand and their causes (3) Integration of communication and electricity (the essence of Watt-Bit) 2. Impact of changes in power demand (1) Data centers as a significant factor (2) Supply chain surrounding data centers 3. Data centers as large-scale demand (1) Demand control and data centers (2) Perspectives of stakeholders surrounding data centers (3) Impact of data centers on the grid (4) Expectations from stakeholders surrounding data centers (5) New technologies anticipated in data centers 4. Current state and future of Watt-Bit (1) Watt-Bit Public-Private Liaison Council (2) Direction of international initiatives (3) Relation to the MESH concept (4) What can be achieved with Watt-Bit 5. Q&A / Business card exchange

[Speaker] Mr. Kei Nishishita, Senior Researcher, Advanced Technology Lab, Japan Research Institute, Ltd. [Key Lecture Content] Neurotech is a collective term for technologies that utilize insights from neuroscience, and in recent years, it has also been referred to as brain tech, with accelerated research and development and commercialization efforts both domestically and internationally. This seminar will systematically organize the foundational technologies and latest trends in the neurotech field, while also highlighting advanced initiatives underway in Japan and abroad, explaining their characteristics and implications. Additionally, considering the current state of neurotech being implemented in society, we will also address changes in the surrounding environment, such as ethics, legal frameworks, and social acceptance. Furthermore, as the integration with the AI field progresses, we will explore what developments can be anticipated in the future and what opportunities and risks may arise in business development from a multifaceted perspective. [Lecture Items] 1. Overview and Current Status of Neurotech 2. Advanced Examples of Neurotech 3. Social Trends Surrounding Neurotech 4. Future Outlook and Strategies for Business Applications 5. Q&A

[Speaker] Takuki Nakani, Representative and Analyst, Nakanishi Automotive Industry Research Co., Ltd. Author of "Toyota vs. Chinese EVs" [Key Lecture Content] A powerful group of the strongest EV manufacturers in the Chinese market and their robust supporting ecosystem are emerging prominently. This is organically linked to China's digital national strategy. As the competitive landscape of the global automotive industry changes with the evolution of SDVs and AI, can Japanese manufacturers chart a path to victory? With an eye on the fragmentation of industrial hegemony, we will examine the future structure of the automotive industry. [Lecture Items] 1. The structure of the battle over intelligence 2. Competitiveness of the strongest Chinese EV manufacturers 3. Japan's OEM strategy against China 4. Japan's path to victory – SDV value chain strategy 5. Evolution of manufacturing accompanying the SDV shift 6. Q&A / Business card exchange

Sansin Manufacturing Co., Ltd. will be exhibiting at the "SURTECH 2026 Surface Technology Elements Exhibition" held at Tokyo Big Sight. At our booth, we plan to showcase wastewater treatment equipment utilizing IoT technology. We look forward to your visit. <Event Overview> ■ Venue: Tokyo Big Sight, South Hall 4 ■ Address: 3-11-1 Ariake, Koto-ku, Tokyo 135-0063 ■ Booth Number: 3S-U22 ■ Nearest Stations: - Rinkai Line: Kokusai Tenjijo Station (approximately 7 minutes on foot) - Yurikamome: Tokyo Big Sight Station (approximately 3 minutes on foot)