[Sending recorded video] Cutting-edge pDNA and AAV therapeutics: Comprehensive upstream process technology covering everything from process development to actual production.

Enhancing equipment performance that influences the success of cultivation! We have achieved improved flexibility.

The "Ambr15 Generation2" is a high-throughput automated micro-scale bioreactor system that replicates the performance of laboratory-scale bioreactors. The system consists of single-use vessels, an automated workstation, and user-friendly software. It is designed to be installed in standard biosafety cabinets for aseptic operations, allowing for parallel monitoring and control of 24 or 48 micro-bioreactor cultures. 【Features】 ■ Reduces operator time and increases work efficiency ■ Facilitates the process of determining the best clone ■ Enables faster and more accurate operations ■ Capable of complex liquid mixing and addition for multifactorial experimental designs (DoE) ■ Used in research facilities worldwide *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

Introducing options and accessories that can be added to the Ambr 15 Generation 2.

You can find the following information in this catalog: ▪ System specifications ▪ Compatible at-line analyzers ▪ Expandable options ▪ Accessories ▪ Ambr 15 microbioreactor (culture vessel) ▪ Plates and chips

• Other physicochemical equipment
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Industry-standard high-throughput bioreactor system optimized for process characteristic analysis.

The Ambr 250 High Throughput Generation 2 is a multi-parallel bioreactor system that accelerates process development and characterization analysis schedules to achieve cost reduction. Its fully continuous gas supply system realizes similarity with large-scale bioreactors and optimizes the scale-down model. Through the integration of analysis options such as the capacitance-based BioPAT Viamass, it supports extensive feedback control.

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• Culture Equipment
• Bioreactor

A fully automated bioreactor system for the development of high-density cell culture processes!

The "Ambr250 Perfusion" is a fully automated multi-parallel bioreactor system that uses single-use culture vessels of 100-250 mL to accelerate the development of scalable perfusion processes. This system allows for the simultaneous execution of up to 24 different perfusion cultures while returning cells to the culture vessel using hollow fibers, which are commonly reported specifications. This system transforms the perfusion processes that could not be achieved with multi-parallel or small-scale setups, reducing experimental costs with small volumes and accelerating the optimization of high-density cell culture processes. 【Features】 ■ Increased productivity / Reduced experimental costs ■ Simultaneous parallel fed-batch and perfusion cultures are also possible ■ Exceptional scalability ■ Sampling and reagent addition are performed by a fully automated liquid handler, reducing daily working hours *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

A single-use benchtop bioreactor with simple operation aimed at improving productivity.

The industry-standard multi-channel, compact fully automated bioreactor, Ambr250 in a benchtop configuration, has arrived with new features and applications for regenerative medicine. It allows for independent cultivation with highly controlled single-use containers with operating capacities of 100-250 mL, arranged in a maximum of 8 channels. There are three types of containers, each specialized for cells, microorganisms, and regenerative medicine, with a refined design that contributes to process development and optimization. Since the containers are single-use and sterilized, they enable fast turnover, accelerating customers' research and development activities. Because it is geometrically identical to bioreactors used for production scale in pharmaceuticals and regenerative medicine products, it is possible to quickly transition and implement optimized cultivation and production conditions.

• Other physicochemical equipment

A new bioreactor system for parallel operation of microbial culture or cell culture!

The "Ambr250" is a new bioreactor system for parallel operations of microbial or cell cultures using single-use bioreactors with a capacity of 100 to 250 mL, controlled by an automated liquid handling platform. This system was developed in collaboration with two major pharmaceutical companies, based on the micro bioreactor technology held by Sartorius Stedim's TAP division. It supports the necessary culture conditions required for microbial cultivation and mammalian cell culture, which demand advanced technology, as well as applications that require larger sample collections. 【Features】 ■ Individual control of all process parameters ■ Improved operating environment ■ Efficient and rapid miniaturization system ■ Equipped for scalability to benchtop bioreactors ■ Capable of screening a wide range of culture conditions and strains or cell lines *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

New user interface

Biostat RM has been renewed with a new control tower that adopts the automation platform Biobrain, which is suitable for commercial production using a shaking-type bioreactor. 【Features】 ▪ Accelerates the market launch of customer products ▪ Simple transition from process development to commercial production ▪ Flexible specifications for diverse manufacturing needs and culture styles ▪ High-precision process control ▪ Support system by technical personnel stationed in various countries

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A single-use bioreactor system that dramatically enhances speed, quality, and productivity from process development to scale-up.

The "Biostat STR Series" is a single-use bioreactor system designed for rapid process development and seamless scale-up to commercial production. The newly launched third generation features a new automation platform, "BIOBRAIN," and the analytical tool "BioPAT(R)," enabling exceptional speed, quality, and productivity. Stable and predictable processes greatly contribute to providing safe and reliable biopharmaceuticals to patients worldwide, accelerating our customers' manufacturing operations and business.

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Seed culture for small-scale protein production.

- The BioStat RM is a single-use rocking bioreactor that is fully compliant with GMP. < BioStat RM 20 | 50 Basic > The BioStat RM 20 | 50 Basic is a standalone bioreactor that is the ideal size for benchtop use. < BioStat RM 200 > The BioStat B and RM 200 Rocker are single-use rocking bioreactors designed for large-scale applications. - The Flexsafe bags have a proven track record with a wide range of cell lines including CHO, NS0, SF9, E. coli, T cells, and mesenchymal stem cells. Using Flexsafe RM bags in the seed train allows for easy scale-up to the BioStat STR single-use bioreactor that utilizes Flexsafe STR bags. The same polyethylene film material can be used for all cell culture steps. Flexsafe RM bags can be used with rocking bioreactors from multiple manufacturers, providing excellent growth characteristics and robustness, with stable supply.

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A multi-talented benchtop bioreactor that supports the research and development of biopharmaceuticals.

"Biostat B" is a benchtop bioreactor equipped with a control tower that possesses multi-talented capabilities to meet the diverse and varied needs of our customers. It offers a multitude of possibilities by combining three types of culture vessels with proven performance in single and twin configurations. With thousands of units delivered in over 50 countries worldwide, our extensive experience and collaboration with customers globally support this track record. [Features] ■ A bioreactor with proven performance worldwide ■ Custom-made devices can be produced to meet customer specifications using our unique design system ■ Established high quality *For more details, please refer to the PDF document or feel free to contact us.

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A fully automated tool for acquiring and fully utilizing Raman spectroscopy data to build a robust cultivation process for the production of uniform and high-quality products.

BioPAT(R) Spectro is a product specifically developed for Quality by Design (QbD). By generating more process data using this product, the potential of Raman spectroscopy can be maximized. This enables the construction of very robust processes, resulting in the production of consistently high-quality products.

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We would like to extend our heartfelt congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will introduce a number of products, including our new product, the Pillow Packaging Full Air Tightness Inspection Machine MSQ-2003. We sincerely apologize for the inconvenience during your busy schedule, but we would like to invite you to visit us at this opportunity. 【 Exhibition Name 】 JAPAN PACK 2025 Japan Packaging Industry Exhibition https://www.japanpack.jp/ 【 Dates 】 October 7 (Tuesday) to October 10 (Friday), 2025 *4 days 10:00 AM to 5:00 PM 【 Venue / Booth Number 】 Tokyo Big Sight / East Hall 8, Booth 8-505

Nitto Kohki will exhibit at the "30th Mechanical Components Technology Exhibition [Tokyo]" held at Makuhari Messe Hall 5 from July 9 (Wednesday) to July 11 (Friday). [Booth Number: Hall 5 31-32] At this exhibition, we will showcase a variety of products, including the electric suction hand "e-VEE" with a built-in pump that does not require compressed air, a cordless belt sander, the electric driver "Delvo" that can be mounted on robots, and the "Flow Monitor" that allows for easy visualization of the flow of cooling water in molds and other applications.

[Instructor] Mr. Tsuyoshi Igarashi, CEO of Leaders Creative Lab Inc. [Key Lecture Content] "Each individual has potential, yet the team fails to achieve results." "Members only do what they are told; they lack proposal skills." "I am struggling with what to do as a leader." "I want to increase the engagement of both members and leaders." "I want to create a self-managing team." Are you facing such concerns and challenges? The daily words and actions of a leader can significantly change the team. When just one leader changes, a team of dozens or even hundreds can achieve remarkable results, even with the same members. We will share know-how from real experiences on how both leaders and members can create a vibrant and fulfilling self-managing team.

[Lecturer] Professor, Aichi Institute of Technology, Comprehensive Technology Research Institute Member, Ministry of Economy, Trade and Industry, Subcommittee on Decarbonized Fuel Policy Member, Carbon Management Subcommittee, among others Mr. Motohiro Kondo [Former Toyota Motor Corporation] [Key Lecture Content] In our country, there are already recycling laws for specific products, and in the automotive sector, appropriate recycling and processing are progressing in accordance with the "Automobile Recycling Law." On the other hand, in response to carbon neutrality and the issue of marine plastic waste, the structure and materials of automobiles themselves are changing, and it is necessary to change our efforts towards recycling used products to facilitate the transition to a circular society. Additionally, some countries have already strengthened their initiatives, starting from addressing these environmental issues, with a focus on enhancing their industrial competitiveness and fostering new industries. In this seminar, we will explain the trends in these foreign countries and our country's policies, as well as efforts towards recycling automotive plastic waste in the formation of a circular society. [Lecture Items] 1. Direction of our country's efforts towards GX and CE 2. Trends in automotive recycling in foreign countries 3. Towards advanced automotive recycling 4. Summary 5. Q&A / Business card exchange

[Lecturer] Professor Kazuhiro Fukushiro, Graduate School of Technology Management, Yamaguchi University [Key Lecture Content] As the electric vehicle (EV) market grows, a pressing issue is the processing of used lithium-ion batteries utilized in EVs. From the perspective of environmental conservation and securing metal resources, the recycling of used lithium-ion batteries has become an urgent challenge. This lecture will explain the current state of upstream processes in recycling, such as the collection and dismantling of used batteries, trends in the development and practical application of recycling technologies like hydrometallurgical and pyrometallurgical processes, and the realities of domestic and international businesses involved in recycling. Additionally, it will touch upon the recycling of solid-state batteries, which are expected to be practical in the future. [Lecture Items] 1. Market trends for EVs and lithium-ion batteries for EVs 2. Structure, positive electrode materials, and lifespan of lithium-ion batteries 3. Collection and dismantling of used lithium-ion batteries 4. Recycling technologies (hydrometallurgy, pyrometallurgy, and others) 5. Development trends in recycling technologies for solid-state batteries 6. Realities and future prospects of the recycling business 7. Q&A