[Exhibition Information] 25th Annual Meeting of the Japanese Society for Protein Science

Easily measure channel activity at the molecular level.

【Measurement Target Examples】 Ion channels (voltage-dependent, ligand-dependent, temperature-sensitive), DNA nanopores, antimicrobial peptides, toxins, etc. In experiments using artificial lipid bilayers, the formation of lipid membranes, reconstitution of membrane proteins, and measurement of single-channel currents can be easily performed. Purified target membrane proteins (such as ion channels in vivo or artificial ion channels) can be reconstituted on artificially formed lipid bilayers, allowing for the evaluation of drug effects and functional/structural analysis. ■ Simultaneous formation and measurement of 4 channels of artificial lipid bilayers is possible ■ Lipid membranes can be formed with just pipetting operations ■ No need for microscope, vibration isolation table, manipulator, or Faraday cage ■ Direct reconstitution of target membrane proteins or membrane fusion with proteoliposomes ■ Temperature control (10–50°C) available (optional) ■ Palm-sized, easy connection via USB

• Other physicochemical equipment
• Analytical Equipment

Easily measure channel activity at the molecular level.

【Measurement Target Examples】 Ion channels (voltage-dependent, ligand-dependent, temperature-sensitive), DNA nanopores, antimicrobial peptides, toxins, etc. Experiments using artificial lipid bilayers allow for easy formation of lipid membranes, reconstitution of membrane proteins, and measurement of single-channel currents. It is possible to reconstitute purified target membrane proteins (such as ion channels found in vivo or artificial ion channels) on artificially formed lipid bilayers for drug action evaluation and functional/structural analysis. By rapidly and automatically forming 16-channel artificial lipid bilayers at once and conducting fully simultaneous measurements, researchers are freed from the burdens of the painting method in experiments using artificial lipid bilayers. ■ Simultaneous formation and measurement of 16-channel artificial lipid bilayers is possible ■ Automatic lipid membrane formation using a stirrer bar ■ No need for microscope, vibration isolation table, manipulator, or Faraday cage ■ Direct reconstitution of target membrane proteins or membrane fusion with proteoliposomes ■ Temperature control available (10–50°C)

• Other physicochemical equipment
• Analytical Equipment

Direct measurement of transporter currents in a label-free and real-time manner without using fluorescent probes or radiolabeled ligands.

Currently, the mainstream method for evaluating transporter activity is the uptake assay using RI-labeled substrates. However, there are several issues, such as the need for specialized experimental facilities, the complexity of waste liquid treatment, the fact that the desired substrates are not always commercially available as RI-labeled, and the measurement of endpoints after uptake. SURFE²R (Surface Electrogenic Event Reader) technology does not require RI labeling, specialized experimental facilities, or waste liquid treatment, and it allows for real-time evaluation of the activity of transporters (symporters, exchangers, unipoters) and pumps. ■ Direct measurement of transporter currents using Solid Supported Membrane (SSM) ■ Experiments can be conducted using membrane fragments prepared from biological membranes or proteoliposomes reconstituted with the target membrane proteins ■ Light stimulation is possible (optional) ■ An all-in-one device that integrates a dispensing machine, measurement section, and computer ■ 150 data points per day

• Other physicochemical equipment
• Analytical Equipment
• Other Analysis

Direct measurement of transporter currents in a label-free and real-time manner without using fluorescent probes or radiolabeled ligands.

Currently, the mainstream method for evaluating transporter activity is the uptake assay using RI-labeled substrates. However, there are several issues, such as the need for specialized experimental facilities, complicated waste disposal processes, the fact that the desired substrates are not always commercially available as RI-labeled, and that the endpoint is measured after uptake. The SURFE²R (Surface Electrogenic Event Reader) technology does not require RI labeling, does not need specialized experimental facilities or waste disposal, and allows for real-time evaluation of the activity of transporters (symporters, exchangers, unipoters) and pumps. ■ Direct measurement of transporter currents using Solid Supported Membrane (SSM) ■ Experiments can be conducted using membrane fragments prepared from biological membranes or proteoliposomes reconstituted with the target membrane proteins ■ Simultaneous measurement in 96 wells ■ 10,000 data points per day

• Other physicochemical equipment
• Analytical Equipment
• Other Analysis

A patch clamp system that incorporates a patch clamp amplifier, achieving miniaturization and reduction of installation costs, allowing for easy data acquisition and verification.

This is a world-class patch clamp system capable of performing gigaseal recordings, optimal for safety testing/toxicity testing/pharmacological testing/screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. ■ No experience with manual patch clamping or difficult operations required ■ No need for microscope/vibration isolation table/manipulator/Faraday cage/puller ■ 20 to 50 data points per day ■ Automation from gigaseal formation to whole cell formation ■ Compatible with voltage-dependent and ligand-dependent channels through pipetting ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications, enabling rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips

• Other physicochemical equipment
• Analytical Equipment
• Patch clamp system

【Seminar Overview】 The construction industry faces many challenges, including labor shortages, regulations on working hours, and the need for operational efficiency. Additionally, the aging workforce presents significant issues, and there is a concerning trend of high turnover rates among younger employees who are supposed to carry on the skills and knowledge. In this seminar, we will discuss the causes of turnover based on case studies and explain key points on how advancing IT can help reduce turnover rates.

We would like to extend our heartfelt congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will introduce a number of products, including our new product, the Pillow Packaging Full Air Tightness Inspection Machine MSQ-2003. We sincerely apologize for the inconvenience during your busy schedule, but we would like to invite you to visit us at this opportunity. 【 Exhibition Name 】 JAPAN PACK 2025 Japan Packaging Industry Exhibition https://www.japanpack.jp/ 【 Dates 】 October 7 (Tuesday) to October 10 (Friday), 2025 *4 days 10:00 AM to 5:00 PM 【 Venue / Booth Number 】 Tokyo Big Sight / East Hall 8, Booth 8-505

We will be exhibiting at the "Monozukuri Fair 2025" held at Marine Messe Fukuoka from October 15 (Wednesday) to October 17 (Friday). "For those in the manufacturing industry who want to advance automation and labor-saving but find the knowledge and cost barriers too high..." Mikasa Trading will introduce solutions that are easy to implement at low cost and have high effectiveness. 【Example of Exhibited Product Lineup】 ■ Collaborative Robot Control Solutions ■ Prototype of Stop Detection Solution ■ AI Camera Solutions for Factories ■ Lenovo PCs for factory edge applications with long-term supply, high reliability, and low cost Please come and find hints to solve your on-site challenges!

FUJI is a leading company in atmospheric pressure plasma devices. In recent years, the introduction of atmospheric pressure plasma as a pre-treatment device to improve adhesive strength and quality has been progressing in manufacturing sites. FUJI's plasma device, Tough Plasma, has world-class processing capabilities and can perform continuous processing at high speeds. At this exhibition, we will showcase the latest model of the Tough Plasma series, "ATOM," which operates solely on air and electricity. Please come and see its world-class capabilities, quality, and safety monitoring features. We will also have a corner where you can experience the effects of plasma treatment firsthand with adhesive sample experiences. If you are having trouble with adhesion, please feel free to stop by our booth. During the exhibition, our engineers will be stationed at the booth. They will be happy to answer any questions you may have, from basic knowledge of plasma to the types of materials that can be processed and processing speed estimates, so please feel free to visit us. You can complete pre-registration from the link below [Details & Application].

[Instructor] Mr. Takashi Momiyama Incubation Producer, Innovation Strategy Center, Japan Research Institute, Ltd. [Key Lecture Content] From the perspective of resource security and the creation of new markets, the realization of a circular economy for EV batteries is anticipated. However, in our country, there are still numerous challenges, and the majority of EV batteries are flowing overseas along with used EVs. In recent years, protectionist policies have been promoted in various countries, such as the U.S. tariff policies and China's rare earth export regulations, and there are concerns that if our country delays its response, the outflow will accelerate further. In light of this situation, we will analyze the impact of geopolitical risks on the formation of a circular economy domestically, overview what initiatives the government, local governments, and private companies have been advancing in the country, and propose measures deemed necessary to further accelerate the formation of a circular economy. We look forward to the participation of individuals from a wide range of industries who may be involved as suppliers or users in the circular economy of EV batteries.