[Sending recorded video] 11/2 [Every Tuesday in Japan] Process Enhancement Series, all 3 sessions - Session 2: High-Throughput Bioreactor Supporting Process Enhancement Efforts

Process enhancement. Modify. Intensify. Amplify.

Process Intensification (PI) is a comprehensive framework aimed at maximizing overall production volume across manufacturing units, manufacturing processes, or biopharmaceutical facilities. Sartorius Stedim offers scalable and versatile modular solutions, including high-throughput process development tools. These can be implemented in current and future manufacturing facilities for a variety of upstream and downstream PI scenarios. - Enables faster drug development - Improves efficiency and productivity in GMP manufacturing - Applicable to various processes regardless of the pharmaceutical ◆ International Webinar [Process Intensification Webinar Series] This webinar series provides a comprehensive guide to maximizing process intensification. It covers upstream and downstream strategies, media management, data analysis, and more. You can watch it here: ⇒ https://bit.ly/3ihwdT1

• Other physicochemical equipment

Industry-standard high-throughput bioreactor system optimized for process characteristic analysis.

The Ambr 250 High Throughput Generation 2 is a multi-parallel bioreactor system that accelerates process development and characterization analysis schedules to achieve cost reduction. Its fully continuous gas supply system realizes similarity with large-scale bioreactors and optimizes the scale-down model. Through the integration of analysis options such as the capacitance-based BioPAT Viamass, it supports extensive feedback control.

• others
• Culture Equipment
• Bioreactor

A fully automated bioreactor system for the development of high-density cell culture processes!

The "Ambr250 Perfusion" is a fully automated multi-parallel bioreactor system that uses single-use culture vessels of 100-250 mL to accelerate the development of scalable perfusion processes. This system allows for the simultaneous execution of up to 24 different perfusion cultures while returning cells to the culture vessel using hollow fibers, which are commonly reported specifications. This system transforms the perfusion processes that could not be achieved with multi-parallel or small-scale setups, reducing experimental costs with small volumes and accelerating the optimization of high-density cell culture processes. 【Features】 ■ Increased productivity / Reduced experimental costs ■ Simultaneous parallel fed-batch and perfusion cultures are also possible ■ Exceptional scalability ■ Sampling and reagent addition are performed by a fully automated liquid handler, reducing daily working hours *For more details, please refer to the PDF document or feel free to contact us.

• Other physicochemical equipment

A fully automated tool for acquiring and fully utilizing Raman spectroscopy data to build a robust cultivation process for the production of uniform and high-quality products.

BioPAT(R) Spectro is a product specifically developed for Quality by Design (QbD). By generating more process data using this product, the potential of Raman spectroscopy can be maximized. This enables the construction of very robust processes, resulting in the production of consistently high-quality products.

• others

Bioreactor system for cell line development and process optimization.

The Ambr1515 Generation 2 is a high-throughput "automated micro-scale bioreactor system" that reproduces the performance of laboratory-scale bioreactors. The system consists of single-use vessels, an automated workstation, and enhanced convenience software. It is designed to be installed in a standard biosafety cabinet for aseptic operations, allowing for parallel monitoring and control of 24 or 48 micro-bioreactor cultures. As the manufacturing processes for biopharmaceuticals become more complex and the density of cultures increases, scientists around the world are facing an unprecedented challenge in developing "clone, medium, and process" that meet new demands. The Ambr15 Generation 2 system enhances equipment performance that influences the success of cultures, improves flexibility, and incorporates new features that reflect user feedback. It helps address the aforementioned challenges and supports the acceleration of research by scientists.

• others

A single-use bioreactor system that dramatically enhances speed, quality, and productivity from process development to scale-up.

The "Biostat STR Series" is a single-use bioreactor system designed for rapid process development and seamless scale-up to commercial production. The newly launched third generation features a new automation platform, "BIOBRAIN," and the analytical tool "BioPAT(R)," enabling exceptional speed, quality, and productivity. Stable and predictable processes greatly contribute to providing safe and reliable biopharmaceuticals to patients worldwide, accelerating our customers' manufacturing operations and business.

• others

Seed culture for small-scale protein production.

- The BioStat RM is a single-use rocking bioreactor that is fully compliant with GMP. < BioStat RM 20 | 50 Basic > The BioStat RM 20 | 50 Basic is a standalone bioreactor that is the ideal size for benchtop use. < BioStat RM 200 > The BioStat B and RM 200 Rocker are single-use rocking bioreactors designed for large-scale applications. - The Flexsafe bags have a proven track record with a wide range of cell lines including CHO, NS0, SF9, E. coli, T cells, and mesenchymal stem cells. Using Flexsafe RM bags in the seed train allows for easy scale-up to the BioStat STR single-use bioreactor that utilizes Flexsafe STR bags. The same polyethylene film material can be used for all cell culture steps. Flexsafe RM bags can be used with rocking bioreactors from multiple manufacturers, providing excellent growth characteristics and robustness, with stable supply.

• others

The latest published paper utilized Abby. This will be an online seminar featuring Associate Professor Yosuke Katsuta from the Graduate School of Advanced Science and Technology, Kumamoto University, who is also a co-founder of StapleBio. He is working on RNA hacking technology development aimed at altering the higher-order structure of target mRNA using short nucleic acids named Staple nucleic acids, with the goal of controlling gene expression. He will present the latest data focusing on the results of cell experiments and animal experiments in the development of this technology. Related paper on the lecture content: "Staple oligomers induce a stable RNA G-quadruplex structure for protein translation inhibition in therapeutics" | Nature Biomedical Engineering

[Speaker] Yoshirō Tsuruhara, Representative of Auto Insight Inc. / Technology Journalist and Editor [Key Lecture Content] The global automotive industry is undergoing significant upheaval. The term "CAST," which is bringing about even greater changes than the previously used keyword "CASE," is at the forefront. It stands for four elements: "China," which has begun to lead global automotive technology; "AI" (Artificial Intelligence), which is transforming the development process; "SDV" (Software Defined Vehicle), which is revolutionizing the creation of vehicle value; and "Trump," which is altering the rules of the world. What does the future of the automotive industry look like with CAST? [Lecture Items] 1. Current state of the automotive industry 2. The keyword "CAST" symbolizing transformation and its meaning 3. How China is dismantling the old order of the automotive industry 4. Generative AI infiltrating all development processes 5. How SDV is transforming "value creation" in the automotive industry 6. How the second Trump administration will change the rules of the global automotive industry 7. Changes in how the automotive industry generates revenue 8. Q&A

[Lecture Items] 1. Energy-saving Project for Data Centers National Research and Development Agency New Energy and Industrial Technology Development Organization Next Generation Green Data Center Technology Development Project Project Manager Toshiyuki Ando 1. About NEDO 2. Overview of the Next Generation Green Data Center Technology Development Project 3. Future of Data Centers 4. Elements Necessary for Energy Saving 5. Overview of Research and Development 6. Q&A / Business Card Exchange 2. Technology Trends of GaN Power Devices Expected to Contribute to Energy Saving in Data Centers and Other Industrial Applications Professor Noriyuki Iwamuro, Tsukuba University, Mathematical and Physical Sciences 1. Current and Future of the Power Device Market 2. Key Points in Power Device Development 3. Technologies Supporting the Latest Silicon MOSFETs 4. Why GaN Devices for Data Centers 5. Latest Technologies of GaN Power Devices 6. Differentiation Between GaN and SiC Power Devices 7. Q&A / Business Card Exchange

This is an announcement for a seminar hosted by our group company, Jemco Japan Management Co., Ltd. ■ Theme: "Mastering 'DX that Can Be Used on the Ground'! Business Reform in Management and Indirect Departments Utilizing DX" ■ Date and Time: November 12, 2025 (Wednesday) 14:00–15:00 ■ Format: ZOOM Webinar 【Seminar Content】 1. The 2030 Problem and Productivity Challenges in Management Departments 2. An Overview of Business Reform Utilizing Digital Technology 3. Automation of Routine Tasks with RPA (Power Automate) 4. Knowledge Search and Document Utilization with Generative AI × RAG 5. Implementation Examples of "Small-Scale DX" with Power Apps 6. Development of DX Talent and Internal Deployment Models If you wish to participate in the seminar, please apply using the URL below. (You will be redirected to the group company's site) *Please apply early as the registration will close once capacity is reached. https://www.jemco.co.jp/seminar/20251112dx/?lfpeid=kqbONicaYDDx&lfmaid=1000360919-5

At our booth, we will propose products that enable "improved production efficiency" and "cost reduction" through the stabilization of plastic molding. In particular, for recycled plastics, which have been gaining importance recently, the representatives of each device will explain the test results verified with demo machines conducted in-house. We will have a demo unit of the polymer moisture meter "AquaTrack V," and customers who bring samples will be able to conduct actual measurements. Larger samples, such as preforms, can also be measured as they are. *Please inquire in advance about the types of samples. Additionally, we will present a booklet titled "Dr. Plastic Molding's Rheology Lecture Notes," summarizing the understanding of material properties and predictions of viscosity and flowability, to those we speak with at the booth. We sincerely look forward to your visit. ◎ Exhibition Contents - Polymer moisture meter "AquaTrack V" (actual machine on display; demo measurements available) - Ultra-compact polymer dehumidifying dryer "Card Series" (full-size mock-up on display) - Capillary rheometer "R6000" (panel on display)