We accept the increase of Tm value, the addition of nuclease resistance, and LNA synthesis.

Insertion into DNA and RNA, combinations with various modifications are also possible! It can be used for applications such as antisense research.

We offer DNA/RNA synthesis services. We support a wide range of nucleic acid synthesis, including cross-linked artificial nucleic acids (LNA), 2’F (fluoro) RNA, 2’MOE (2’-O-methoxyethyl) RNA, and 2’-OMe RNA. These can be utilized for applications such as antisense research and partial incorporation into dual-labeled probes. We can also accommodate insertions into DNA and RNA, as well as combinations with various modifications, so please feel free to consult us. 【Overview】 ■ Nucleic Acid Derivatives ・Artificial Nucleic Acids (LNA) ・2’F (Fluoro) RNA ・2’MOE (2’-O-methoxyethyl) RNA ・2’-OMe RNA ■ Nuclease-Resistant Modifications ・S-Oligo (Phosphorothioate) ・Inverted dT, etc. *For more details, please refer to the PDF document or feel free to contact us.

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The "24 Tissue Tubes 3.0ml Type" features a wide inner diameter of 13.4mm at the mouth, a low height of 25.9mm, and a flat bottom design, making it easy to insert and remove samples. Each tube is equipped with a 2D code on the bottom, allowing for efficient sample information management by using a 2D scanner to reflect the code in a PC database. Additionally, it is compatible with automated systems due to its SBS format. 【Features】 ■ Easy insertion and removal of samples ■ Particularly suitable for tissue/cell samples measuring 5mm to 7mm ■ Using our dedicated rack for 24 tubes allows for bulk reading of the 2D codes on the tube bottoms ■ Compatible with automated systems due to its SBS format ■ Made of polypropylene, autoclavable, and compatible with DMSO *For more details, please refer to the related links or feel free to contact us.

■Disadvantages of Conventional Antistatic Fluororesin Coatings - Requires high-temperature firing (around 400°C) - Applicable only to metals - Limited color options - Low mechanical strength ■Features of Safron LF+ - Can be processed at low temperatures (below 100°C) - Applicable to metals and resins - Color variations available - High friction coefficient and mechanical strength - Antistatic performance is equivalent to conventional Safron For more details, please check the product site.

The "Mechanical Stitching Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed, and repairs are made without causing any thermal impact to the base material. Repairs can be carried out in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.

The "Mechanical Stitch Method" by Nichinichisui Road Machinery Co., Ltd. is a new technique that allows for the repair of metal cracks without the application of heat. By using special bolts and reinforcement plates, cracks are physically removed, and repairs are made without causing any thermal impact to the base material. Repairs can be carried out in environments where open flames cannot be used. Since no heat is applied, the disassembly of equipment is minimized. ◎ For more details, please contact us. ◎ If a detailed technical explanation is needed, please contact us.

<Title> Development of Gene Expression Control Technology through RNA Hacking In the latest presentation paper, we have utilized Abby. Associate Professor Yosuke Katsuta from Kumamoto University Graduate School of Advanced Science and Technology, Analytical Chemistry Laboratory (also co-founder of StapleBio), will be giving a presentation in an online seminar. He is working on the development of RNA hacking technology aimed at controlling gene expression by utilizing short nucleic acids named Staple to change the higher-order structure of target mRNA. He will present the latest data focusing on the results of cell experiments and animal experiments in the development of this technology. Related paper on the presentation content: Staple oligomers induce a stable RNA G-quadruplex structure for protein translation inhibition in therapeutics | Nature Biomedical Engineering