Poster presentation on HTLV-1 clonal analysis technology.

Developed through joint research with the National Institute of Infectious Diseases. Achieves determination of the insertion site of foreign DNA in a short time, with high sensitivity and low cost.

The "RAISING method" is a technique for detecting the insertion sites of foreign DNA in the genome. It allows for rapid and reproducible measurement results with a small amount of DNA. It can identify insertion sites of viral genome insertions, viral vector insertions, searches for fusion genes that could be drug discovery targets, and off-target knock-ins in genome editing, among others. 【Features】 - Analysis can be arranged according to the purpose and target. - Multiple insertion sites can be detected in a single analysis. - High reproducibility of results is achieved through proprietary technology. 【Analysis Examples】 - HTLV-1 (Human T-cell Leukemia Virus) Clonality Analysis Leveraging the characteristics of the RAISING method, which can quickly detect with a small amount of DNA, we achieved high detection sensitivity even with a proviral load of 0.032%. - Off-target Detection of Knock-ins in Genome Editing For knock-in mice created using CRISPR/Cas, we conducted detection of knock-in efficiency and off-target sites by combining with NGS. *For details on examples and services, please refer to the materials available for download.

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Features ● Equipped with Intel Core i9-13900E/i5-13500E *Optional upgrade available ● 64GB memory installed *Optional upgrade available (up to 128GB) ● 2.5-inch 3D TLC SSD 512GB installed *Optional upgrade available ● Windows 11 IoT Enterprise installed *Optional upgrade available ● HDMI x1, DP x1, VGA x1 ports available ● Rear I/O side USB 3.2 Gen 2 x4, USB Type-C x1, GbE x2, 2.5GbE x2, RS-232/422/485 x1

Features ● Equipped with Intel Core i9-13900E / i5-13500E *optional change available ● Equipped with 64GB memory *optional change available ● Equipped with 512GB 3D TLC SATA SSD *optional change available ● Equipped with Windows 11 IoT Enterprise *optional change available ● HDMI x2, DP x2 included ● Rear I/O includes USB 3.2 (Gen2) x3, USB 3.2 (Gen1) x2 ● BTO support available from one unit

Features ● Compatible with 12th/13th/14th generation Intel Core i series ● Equipped with 32GB memory and 512GB 3DTLC SSD *Changeable as an option ● Comes with Windows 11 IoT Enterprise *Changeable as an option ● Equipped with 1 HDMI, 1 DP, and 1 VGA port ● Rear I/O includes 4 USB 3.2, 4 LAN, and 1 COM ● Long-term supply model ● BTO options available from a single unit, allowing changes to CPU, memory, etc.

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