[Sending recorded video] 4Cell Nutri-T Medium - Serum-free medium for the culture of CAR-T cells and TIL.

Excellent results and flexibility with xenofree serum-free medium for lymphocyte culture!

Cell-based immunotherapy is at the forefront of cancer treatment. The most common type of cell-based immunotherapy to date is T-cell therapy (with CAR-T and TIL being the mainstream). The cells used in immunotherapy are generally cultured in a medium supplemented with human serum. The use of serum introduces variability in the process due to individual differences among donors, leading to inconsistencies in cell growth and characteristics. By removing this serum and simplifying the process, regulatory risks are reduced, and the associated logistical burdens are alleviated. Nutri-T eliminates the need for serum by replacing its essential components with specific proteins, lipids, and other small molecules. <Product Overview> ■ Xeno-free ■ Serum-free, no serum supplementation required ■ Compliant with ISO13408 ■ For research use only ■ Developed using cells from actual cancer patients ■ Excellent results with PBMC, TIL, and CAR-T ■ Outstanding results at low initial seeding density

• others

An all-in-one solution designed for freezing and thawing cells, with a known chemical composition, particularly for cell therapy and clinical applications.

NutriFreez D5 Salt Based Cryopreservation Solution provides an environment that can protect cells even at ultra-low temperatures (-196°C), ensuring high survival rates, recovery rates, and performance for very delicate cells. It is manufactured under current GMP conditions and demonstrates industry-leading performance. This product is optimally formulated, containing 5% DMSO, and does not include antibiotics, antifungals, hormones, growth factors, serum, or proteins.

• others

A cost-effective and efficient standardized supplement designed to adhere human mesenchymal stem cells under serum-free and xeno-free culture conditions.

NutriCoat Attachment Solution is a cell adhesion substrate designed for human mesenchymal stem cells (hMSC) based on human fibrinogen, suitable for serum-free and xeno-free culture. It is optimized for human MSC derived from various tissues cultured in MSC NutriStem XF Medium. Additionally, it supports long-term culture of hMSC and the results of colony-forming unit-fibroblast (CFU-F) assays under serum-free and xeno-free culture conditions. This product is a ready-to-use solution that can be stored at room temperature, making it ideal for experiments in cell therapy research.

• others

Redefining the excellence of stem cells and advancing clinical applications: a complete xenofree serum-free system for the proliferation and expansion of hMSCs.

MSC NutriStem XF medium is a xeno-free medium for human mesenchymal stem cells (MSC) derived from various tissues such as bone marrow, fat, and Wharton's jelly. It supports the long-term culture of human MSC while maintaining the fibroblast-like morphology, self-renewal ability, and multipotency observed in normal MSC. MSC Attachment Solution - Xeno-free, purified human fibronectin/fibrinogen - Optimized for serum-free culture - For the proliferation and differentiation of hMSC MSC Dissociation Solution - Ready-to-use, known chemical composition - Recombinant trypsin solution NutriFreez D10 Cryopreservation Solution - Known chemical composition, animal-derived component-free, protein-free - Excellent cell adhesion and viability

• others

Xeno-free serum-free medium for hES cells and hiPS cells

NutriStem hPSC XF will be registered with the U.S. FDA Drug Master File (DMF)! NutriStem hPSC XF medium is a xeno-free (XF) medium optimized for the culture of human iPS/ES cells. It contains no animal-derived components and is composed entirely of human-derived proteins. NutriStem hPSC XF Medium has the capability to culture human pluripotent cells without the need for high concentrations of bFGF or other stimulatory growth factors or cytokines, enabling long-term culture while maintaining undifferentiated potential under both feeder-free (Matrigel coated) and on-feeder (MEF, HFF) conditions.

• others

Kanadebia Co., Ltd. will be exhibiting at the "9th Railway Technology Exhibition 2025 Mass-Trans Innovation Japan 2021" held at Makuhari Messe. This exhibition has been held since 2010 as a comprehensive trade fair where various railway-related technologies, including railway and transportation systems, infrastructure technology, facilities, power, transportation, operation management, vehicles, interiors, and passenger services, come together. We sincerely look forward to your visit.

This is a course where you can systematically learn the knowledge and skills necessary for management positions from the perspectives of leadership and labor management, and strengthen your "ability to motivate people." It is open to one participant per company. Content: - The ideal image of a leader - Team building that creates results - Ways to communicate that engage people - Methods for guiding and developing subordinates - Rules of labor management - Prevention of harassment - Mental health in the workplace Here are some comments from participants: - I have dreamed of becoming the best team, so I will share this with my members and take steps forward! - If I communicate what I am not doing to the staff, I won't gain their support. I will express it through my own actions. - The phrase "Strategies to enhance motivation without human relationships are meaningless" resonated with me. - I had no knowledge about labor issues, and it was a learning experience. I will study to be able to respond as a leader. We look forward to your participation. *Details can be downloaded from "Product Information." *For inquiries and applications, please contact us below or visit our website or call us. *Registration will close once we reach capacity.

We want to improve our operations with AI, but what exactly can we do... For those who want to actually try out and compare services, we have an announcement. The electronic contract and document management service paperlogic will be exhibiting at the 'Business Innovation Fair 2025 Autumn in Makuhari' hosted by Otsuka Shokai on November 13th (Thursday) and 14th (Friday) at the Hotel Green Tower Makuhari. Seminars on business improvement and AI utilization will also be held, so if you are nearby, please come and visit us. ● We will also be conducting product demonstrations of paperlogic at the venue. The biggest feature of paperlogic is that it is easy to use and simple, yet it complies with all document management regulations, including the Electronic Bookkeeping Act. We invite you to experience this simplicity firsthand.

What should we start with for the digital transformation (DX) in the quality assurance department? ■ Transitioning from manual input to automatic input for inspection sheet creation! ■ Connecting measurement result input tasks to digital calipers for automatic judgment! We propose to not only maximize the use of CAD drawings to streamline inspection operations but also to initiate the digital transformation starting from inspection tasks.

The electric actuator manufacturer LINAK will be exhibiting for the first time at the "International Robot Exhibition (iREX 2025)" held at Tokyo Big Sight. This exhibition is highly regarded both domestically and internationally as "one of the largest robot specialized exhibitions in the world." At the venue, we plan to showcase our lifting column "LC3 IC Elevate," which is suitable for lifting applications with collaborative robots, as well as electric cylinder solutions for AGV/AMR. We will propose sustainable and flexible automation solutions. Please be sure to visit our booth.