An easy-to-handle electric micromanipulator optimal for the manipulation of suspended cells.
This is an easy-to-use electric micromanipulator that is optimal for the micromanipulation of suspended cells. It is ideal for the transfer of ES cells and iPS cells, the creation of transgenic animals, and ICSI. The electric design allows for accurate and precise work, with the capillary driven in proportion to the joystick movements, enabling intuitive operation. Features such as position saving and driving range limitation allow manipulation tasks, which previously required skill, to be performed efficiently and easily even by beginners. It offers flexible adjustment of installation position and capillary angle, accommodating a wide range of experimental techniques.
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【Intuitive, Accurate, and Precise Operations Possible】 The movement of the joystick is proportional to the movement of the capillary, allowing for intuitive operation. With a maximum operating speed of 10,000 μm/s and the ability to move the capillary in increments of 20 nm, rapid and precise operations are achievable. The drive speed can be easily adjusted finely using an independent dial and a switch key for coarse, fine, and ultra-fine movements. The unique DualSpeed joystick makes it easy to move over long distances. 【User-Friendly Features for Efficient Work Even for Beginners】 Various features enable complex micromanipulation tasks to be performed efficiently and easily by beginners. Up to 5 positions can be saved, allowing the capillary to move to the saved position with the push of a button. Drive range limits can be set to prevent mistakes such as damage to the capillary or collisions with the condenser. 【Flexible Adjustments and Compatibility with a Wide Range of Experimental Techniques】 The adjustment range for installation positions is broad, allowing for flexible addition of accessories. The angle of the capillary can be easily adjusted from 0 to 90°, accommodating a wide range of applications. Adapters compatible with major microscope manufacturers are available.
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Applications/Examples of results
**Microinjection into Suspended Cells** > Creation of transgenic animals using injections into pronuclei or cytoplasm (e.g., TALEN) > Experimental techniques in reproductive medicine for animals (e.g., mouse ICSI) > Continuous injection into fish embryos (e.g., zebrafish, medaka) > Injection into nematodes and other worms, insects, etc. **Manipulation of Suspended Cells** > Transfer of stem cells > Transfer of nuclei > Cell transplantation > Selection and isolation of single cells (e.g., biopsy) **Other Experimental Technique Examples** > Semi-automatic microinjection into adherent cells > Positioning and selection of microparticles > Microdissection of chromosomes, etc. > Automatic dispensing of cell suspensions or solutions
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