Introduction to platform technologies in drug discovery business.
Our drug discovery business is focused on controlling protein-protein interactions. We are developing our business based on two pillars: one is the research and development of small molecule drugs based on our unique "in silico molecular design method, INTENDD (Interprotein's Engine for New Drug Design)." The second is the research and development of medium-sized molecule drugs using peptide technology with a "helix-loop-helix" structural motif. [Business Overview] ■ INTENDD ■ Helix-loop-helix structural regulatory peptides *For more details, please refer to our catalog or feel free to contact us.
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basic information
【Business Description】 ■INTENDD - A method for exploring compound binding sites using 3D models (3D prints) that emphasize shape complementarity, devised, implemented, and accumulated by our advisor, Dr. Yuji Matsuzaki, who is a pioneer in this field. - A unique compound design technology based on a proprietary algorithm that emphasizes shape complementarity (SBSG method: Structure Based Scaffold Generation). ■Helix-loop-helix structural regulatory peptides - To complete the foundation of drug discovery molecules, two peptides with helical structures are connected by two loops, allowing for the free arrangement of amino acids in a helix-loop-helix structure, enabling the creation of a new type of peptide that strongly binds to target molecules. - Achieves high stability in vivo, which has been a challenge in peptide drug discovery, allowing for unprecedented types of peptide drug development. - Adaptable to target molecules both inside and outside cells, with no need for structural information of the target molecules. Additionally, it can be produced through organic synthesis, differentiating it from conventional antibody drugs and small molecule pharmaceuticals. *For more details, please refer to the catalog or feel free to contact us.
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For more details, please refer to the catalog or feel free to contact us.
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Company information
Our company has the management philosophy of "contributing to the health and welfare of humanity by supplying pharmaceuticals to patients around the world" and aims to create "innovative, versatile pharmaceuticals that minimize the burden of medical expenses from the patient's perspective" as our management vision. We operate in two main areas: our core business of "drug discovery" and the "consulting business related to drug discovery," which handles advisory services such as business development and research and development.