Modeling tool for solid and powder processes 'gFORMULATE'
gPROMS FormulatedProducts 1.6.0
Process model library (reaction, crystallization, wet and dry grinding, spray drying, wet and dry granulation, blending, and tablet compression, etc.)
gPROMS Formulated Products is equipped with a library of process models for operations such as reactions, crystallization, wet and dry milling, spray drying, wet and dry granulation, blending, and tablet compression. In case studies applied to pharmaceutical processes, it enables consistent performance analysis of the entire system from active pharmaceutical ingredient (API) manufacturing through formulation processes to oral absorption risk analysis. ■ Solution crystallization analysis ■ Solid-liquid and solid-gas separation, classification, and granulation process analysis ■ Oral absorption analysis This product was developed with the cooperation of major pharmaceutical companies in Europe and the United States. By using mathematical models of raw materials, unit operations, and product performance, it allows for formulation design aimed at optimizing pharmaceuticals and their manufacturing. It enables faster screening of new formulation candidates against quality attributes, including in vivo performance and manufacturability.
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basic information
gPROMS FormulatedProducts allows you to select the necessary components for the basic platform. The functionalities for Simulation (steady state and dynamic) and GSA (Global System Analysis) are standard features. <Optional Features> * Flowsheet Construction & Modification * Custom Modelling * Optimisation: Process optimization considerations * Parameter Estimation * gPROMS High Performance Computing * Hybrid Multizonal gPROMS/CFD Interface * gSAFT – SAFT equation of state * Multiflash/Multiflash DIPPR and more <Optional Libraries> ■ Solution crystallization analysis ■ Solid-liquid and solid-gas separation, classification, granulation process analysis ■ Oral absorption analysis
Price information
For your reference: 3 million to 8 million (per year) We accept contracts on a monthly basis.
Delivery Time
P2
Applications/Examples of results
In the case applied to the pharmaceutical process, it is possible to achieve consistent overall system performance from active pharmaceutical ingredient manufacturing through the formulation process to risk analysis of oral absorption. PSE regularly conducts free training sessions regarding this product. Anyone is welcome to participate. Since the release of gPROMS FormulatedProducts 1.3 in December 2018, a food manufacturing process and mining process library have been added. The food manufacturing process library is the result of collaborative research with world-leading food nutrition organizations, and it includes models for membrane filtration, thermal processing, falling film evaporators, and multi-stage spray drying. In the recent version upgrade (gPROMS FormulatedProducts 1.6), a reaction calorimeter model and an HPLC model have been added. If you would like materials on software application cases, please contact us.
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Company information
Founded in 1997 by the gPROMS development team at Imperial College London, PSE became part of the Siemens Group in 2019 and has been providing products and services in Japan as Siemens Corporation since 2023. gPROMS features a powerful equation-based computation engine that differs from traditional simulators, allowing for seamless handling of both steady-state and dynamic simulations. This enables the effective scaling up of models adjusted with experimental data from batch processing for the design and operational optimization of continuous processing plants. With gPROMS's excellent capabilities in custom modeling, parameter estimation, and optimization, it is possible to quickly build optimal manufacturing processes, resolve issues, and achieve optimization.