Support for toxicity testing from the screening stage to entering clinical trials!
Inari Research supports toxicity testing from the screening stage until entering clinical trials (clinical studies). We conduct a wide range of tests based on our extensive testing experience and accumulated background data in standard test systems such as mice, rats, rabbits, dogs, and of course, monkeys. The tests are conducted in a GLP-compliant facility that has obtained certification from AAALAC International (Association for Assessment and Accreditation of Laboratory Animal Care International). We can complete a series of non-clinical test sets, including genotoxicity tests and safety pharmacology tests necessary to enter clinical trials (Phase I), with the final report preparation finished within six months. 【Main Types of Tests】 ■ Single-dose tests ■ Expanded single-dose toxicity tests ■ Repeated dose tests for 2 weeks, 4 weeks (1 month), 13 weeks (3 months), 26 weeks (6 months), 39 weeks (9 months), and 52 weeks (12 months) ■ Various dose-setting tests ■ General toxicity tests in the drug discovery exploration stage, etc. *For more details, please refer to the PDF document or feel free to contact us.
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【Animal Species】 Mouse, rat, rabbit, guinea pig, hamster, dog, monkey 【Routes of Administration】 Oral (forced, mixed feed), intravenous (bolus, long-term infusion using infusion pump), intraperitoneal, subcutaneous, intradermal, intramuscular, ocular, transdermal (application, patch), rectal, intra-articular, oral mucosa, etc. 【Observations and Tests, Measurements】 General condition, body weight measurement, food and water intake measurement, ophthalmological examination, auditory examination, electrocardiogram examination, blood pressure measurement, body temperature measurement, clinical tests, necropsy, organ weight measurement, pathological histological examination, etc. 【Toxicokinetics】 Measurement of the concentration of the test substance and its metabolites in biological samples *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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Our company is located in the nature-rich city of Ina, Nagano Prefecture, surrounded by two Alps, and has been serving our customers as a non-clinical trial contract research organization (CRO) for 50 years. Since 2022, we have become a member of the Shin Nippon Science Group, expanding and enhancing our contract testing items and analyses, and we can quickly respond to the procurement of various testing materials (such as animals). Non-Clinical Trial Business We accept safety and efficacy testing for pharmaceuticals, chemicals, pesticides, food, medical devices, and more. We conduct in vivo tests using small animals, rabbits, dogs, and monkeys, as well as in vitro tests using bacteria and cells, and various alternative method tests. Additionally, we specialize in the creation of SEND data required for FDA applications for new drugs, and we also undertake work related to SEND conversion and QC for data creation and conversion only. Our facility was the first in Japan to obtain full accreditation from AAALAC International (the Association for Assessment and Accreditation of Laboratory Animal Care International), and we are committed to international standards of animal welfare. We also propose tests necessary for various applications and registrations in compliance with regulations in different countries and regions.