OECD test guideline compliant! Conducting acute toxicity tests and subchronic/chronic toxicity tests.
We support the toxicity tests required for the registration application of new pesticides and formulations from the screening stage. We conduct tests using standard test subjects such as mice, rats, rabbits, dogs, and primates, as well as alternative methods using cultured cells, which have been increasingly requested both domestically and internationally in recent years. Inari Research is a GLP-compliant facility and has obtained certification from AAALAC International (the Association for Assessment and Accreditation of Laboratory Animal Care International). We conduct in vivo/in vitro tests in accordance with the regulations related to new pesticide applications and safety evaluations of pesticide formulations in various countries, as well as OECD guidelines. Additionally, we offer consulting on toxicity evaluations based on the regulations of each country. 【General Toxicity Tests】 - Conduct acute toxicity tests, as well as subchronic and chronic toxicity tests. - The test supervisor communicates with clients while conducting the tests. - Various necessary examinations and their evaluations are supported by experienced researchers and technicians. *For more details, please refer to the PDF document or feel free to contact us.
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【General Toxicity Testing】 ■Main Types of Tests - Acute/Subacute toxicity tests to evaluate short-term effects - 90-day repeated/1-year chronic toxicity tests to evaluate long-term effects - Various dose-setting tests - General toxicity tests for screening purposes, etc. ■Animal Species - Mice, rats, rabbits, dogs, monkeys ■Routes of Administration - Oral (forced, mixed feed), intravenous, intraperitoneal, ocular, dermal (application, patch) ■Observations and Tests, Measurements - General condition, body weight measurement, food and water intake measurement, ophthalmological examination, clinical tests, necropsy, organ weight measurement, pathological histological examination - Optionally, auditory tests, electrocardiogram tests, blood pressure measurement, body temperature measurement ■Toxicokinetics - Measurement of the concentration of the test substance and its metabolites in biological samples *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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Our company is located in the nature-rich city of Ina, Nagano Prefecture, surrounded by two Alps, and has been serving our customers as a non-clinical trial contract research organization (CRO) for 50 years. Since 2022, we have become a member of the Shin Nippon Science Group, expanding and enhancing our contract testing items and analyses, and we can quickly respond to the procurement of various testing materials (such as animals). Non-Clinical Trial Business We accept safety and efficacy testing for pharmaceuticals, chemicals, pesticides, food, medical devices, and more. We conduct in vivo tests using small animals, rabbits, dogs, and monkeys, as well as in vitro tests using bacteria and cells, and various alternative method tests. Additionally, we specialize in the creation of SEND data required for FDA applications for new drugs, and we also undertake work related to SEND conversion and QC for data creation and conversion only. Our facility was the first in Japan to obtain full accreditation from AAALAC International (the Association for Assessment and Accreditation of Laboratory Animal Care International), and we are committed to international standards of animal welfare. We also propose tests necessary for various applications and registrations in compliance with regulations in different countries and regions.