Real-time measurement of the details of cells in solution! For cell structure inspection and drug discovery testing.
The newly developed laser phase contrast microscope, unlike the conventional Zernike-type phase contrast microscope, not only enables "imaging of refractive index changes in phase objects such as cells" but also achieves "imaging through interference" using coherent parallel laser light illumination. 【Features】 ■ Non-invasive, wide-field, and deep depth of field observation method for phase objects using parallel laser light illumination ■ Accurate observation of transparent object shapes and sizes without halos using parallel laser light illumination ■ Clear imaging technology through the capture of higher-order diffracted light from refraction and scattering at the nucleus and periphery of transparent biological cells *For more details, please contact us or download the PDF for more information.
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Traditionally, when observing phase objects (such as colorless transparent specimens, living cells, bacteria, etc.) without staining, phase contrast microscopes have been used. In phase contrast observation, the phase differences caused by refractive index and thickness are converted into variations in image brightness; however, this does not represent the shape of the objects. Additionally, it is said that samples with excessively large phase differences or those that are too thick are not suitable for phase contrast observation.
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The Advanced Technology Research Institute has successfully commercialized a laser phase contrast microscope that allows for the non-staining observation of transparent objects such as biological tissues, cells, and bacteria, and has begun accepting orders. We believe it will be useful not only for the culture and examination of iPS cells but also in the fields of biological sciences and medicine, as well as in the development of bioscience products such as cosmetics and health foods. We would be grateful if people from various fields could view and evaluate the product materials and images of the "Laser Phase Contrast Microscope FTM1," which features a novel optical system.