Comprehensive quantification and identification of trace proteins is possible!
Exosomes are gaining attention as targets with new biomarkers, and there is a demand for high-precision analysis of the proteins contained in exosomes. When analyzing blood samples, it is necessary to identify extremely small amounts of target molecules that are only present in exosomes secreted from the disease site, among the overwhelming majority of exosomes derived from normal cells. For this purpose, proteomics analysis methods that allow for the identification of more proteins and quantitative comparisons between samples are the optimal means. In DIA proteome analysis, we conduct proteome analysis using the Data-independent acquisition (DIA) method, which is renowned for its analytical depth and quantitativeness, with the state-of-the-art mass spectrometer Q-Exactive HF-X (Thermo Fisher Scientific). This method allows for the observation of up to 8,000 types of proteins in a single analysis and enables quantitative comparisons of individual proteins between samples. This service is a one-stop service that consistently handles everything from sample preparation to DIA proteome analysis, so customers can obtain high-depth proteome analysis data simply by sending in their samples.
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basic information
Service Menu ▶ Exosome preparation from samples ▶ Protein expression and relative quantification analysis using simple DIA proteomics ▶ Protein expression and relative quantification analysis using DIA proteomics ▶ Protein expression and relative quantification analysis using high-depth DIA proteomics ▶ Option: Sample cleanup processing ▶ Option: Repeated measurements
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Proteome analysis of exosomes
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Company information
Hakarel Co., Ltd. primarily supports research on exosome detection methods and offers contract services such as the production of recombinant proteins, the creation of monoclonal antibodies, the establishment of ELISA measurement systems, exosome ELISA measurements, and proteomics analysis. We respond flexibly to customer requests and provide support for research and development. Please feel free to contact us if you have any inquiries.