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  6. Improving the separation of ionic compounds using "ion-pair reagents" for HPLC!

Improving the separation of ionic compounds using "ion-pair reagents" for HPLC!

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last updated:Aug 11, 2021

関東化学株式会社 バイオケミカル部
関東化学株式会社 バイオケミカル部
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Recommended for reverse phase chromatography: Improve the chromatographic analysis issues of samples containing ionic compounds! Suppress dissociation and increase retention to the stationary phase.

"Ion Pair Reagent" is a reagent for HPLC. In chromatographic analysis of samples containing ionic compounds, issues may arise with solute retention and peak shape. In such cases, it is known that adding an ion pair reagent to the mobile phase can improve separation, and it is particularly useful in reverse phase chromatography. When this reagent is added to the mobile phase, ions of opposite charges attract each other to form neutral ion pairs, which suppresses the dissociation of the sample in the mobile phase. Additionally, since the ion pair reagents are bonded with various alkyl groups, the formed ion pairs become more lipophilic, resulting in increased retention on ODS packing materials. We offer a lineup for both basic and acidic samples. If you require more guarantee items for use in pharmaceutical testing, we can provide a quote. Please feel free to consult us. In addition, we handle other HPLC reagents: ◇ Solvent for High-Performance Liquid Chromatography HLC-SOL ◇ For LC/MS ◇ For pharmaceutical testing ◇ Pre-prepared mobile phases (custom orders available) …etc. For more details, please download the catalog or feel free to contact us.

    Chemicals
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Improving the separation of ionic compounds using "ion-pair reagents" for HPLC!

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イオンペア.png RCA-00液体クロマトグラフィー用関連製品.png RCA-01液体クロマトグラフィー用溶媒・試薬.png
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In the chromatography analysis of samples containing ionic compounds, issues may arise with solute retention and peak shape. In such cases, a method known to improve separation involves adding ion-pair reagents to the mobile phase, which is particularly useful in reverse phase chromatography. 【Product Lineup】 ◇ Sodium 1-decanesulfonate ◇ Sodium n-dodecyl sulfate ◇ Sodium 1-heptanesulfonate ◇ Sodium 1-hexanesulfonate ◇ Sodium 1-nonanesulfonate ◇ Sodium 1-octanesulfonate ◇ Sodium 1-pentan sulfonate ◇ Tetra-n-butylammonium hydrogen sulfate ◇ Tetra-n-butylammonium hydroxide solution ◇ Tetra-n-butylammonium phosphate solution If you require more guarantee items for use in pharmaceutical testing, we can provide a quote. Please feel free to consult with us.

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Detailed information

  • RCA-00液体クロマトグラフィー用関連製品.png

    Comprehensive Catalog ≪Products Related to Liquid Chromatography≫ We provide detailed information on products related to liquid chromatography. A wide range of items, including columns and solvents, are included. 【Table of Contents (Excerpt)】 ◇ HPLC Columns ◇ Related Products for Column Chromatography ◇ Related Products for Thin Layer Chromatography ◇ Solvents and Reagents for HPLC ◇ Sample Preparation Products ◇ Equipment Products

  • RCA-01液体クロマトグラフィー用溶媒・試薬.png

    Product Catalog: Solvents and Reagents for Liquid Chromatography We provide detailed information on "HLC-SOL Solvent for High-Performance Liquid Chromatography" and "Prepsol Solvent for Preparative Liquid Chromatography." Each solvent's features and specifications are included. 【Product Lineup】 ◆ HLC-SOL for High-Performance Chromatography Plus Series (with particle guarantee) Compatible with three systems (for pharmaceutical testing) For LC/MS Premixed products Ion-pair reagents Deuterated solvents ◆ Prepsol for Large-Scale Preparative Chromatography

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Model number overview
37453-53 1-Decanesulfonic acid sodium salt
37203-33 n-Dodecyl sulfate sodium salt
37431-43 1-Heptanesulfonic acid sodium salt
37457-43 1-Hexanesulfonic acid sodium salt
37449-53 1-Nonanesulfonic acid sodium salt
37447-43 1-Octanesulfonic acid sodium salt
37423-43 1-Pentanessulfonic acid sodium salt
40465-43 Hydrogen sulfide tetrabutylammonium
42012-1A Tetrabutylammonium hydroxide solution 100g
42012-2A Tetrabutylammonium hydroxide solution 500g
40466-53 Tetrabutylammonium phosphate
42017-1A Tetrabutylammonium phosphate solution

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Kanto Chemical Co., Inc. Related Products for Liquid Chromatography [Comprehensive Catalog]

Kanto Chemical Co., Inc. Related Products for Liquid Chromatography [Comprehensive Catalog]

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Solvents and reagents for liquid chromatography

Solvents and reagents for liquid chromatography

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Product List of Solvents and Reagents for Liquid Chromatography

Product List of Solvents and Reagents for Liquid Chromatography

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関東化学株式会社

関東化学株式会社 バイオケミカル部

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Since its establishment in 1944, Kanto Chemical has continued to develop competitive products in four fields: reagents, electronic materials, clinical diagnostic reagents, and chemical products, under a strict quality control system as a comprehensive reagent manufacturer.

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