It can be used to predict the permeation of drugs in biomembranes similar to skin, using fillers that form immobilized artificial membranes similar to natural cell membranes.
IAM stands for Immobilized Artificial Membrane, which was developed for the separation and purification of membrane proteins. It is a filler that forms an immobilized artificial membrane similar to natural cell membranes and can also be used to predict the permeation of drugs in biological membranes, such as skin.
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basic information
IAM.PC is a filler that immobilizes phosphatidylcholine on silica, demonstrating a strong affinity for membrane proteins, making it effective for the purification of membrane proteins and the study of drug-protein interactions. IAM.PC.DD2 A filler that is end-capped with C10/C3 alkyl groups using IAM.PC filler.
Price range
P3
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Applications/Examples of results
It can be used to predict the permeation of drugs in biomembranes similar to skin, using fillers that form immobilized artificial membranes similar to natural cell membranes.
Detailed information
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Chemical structure of the stationary phase
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Company information
Kemco Plus Co., Ltd. is a company located in Higashi-Osaka City, Osaka Prefecture, that develops, manufactures, and sells scientific separation and analysis equipment, particularly high-performance liquid chromatography (HPLC) related devices, as well as filling columns for HPLC packing materials and the export and import of related products. Based on 37 years of achievements and experience from its predecessor, the company sells its own developed brands Chemcosorb and Chemcobond, in addition to filling well-known packing materials such as Nucleosil, Hypersil, and MCI-GEL, which are packed in-house and sold as ChemcoPak columns. The unique packing technology cultivated through the development of HPLC column packing equipment has received high acclaim in the market.