Natural amino acid 'Polylysine' as an additive in food preservatives, hygiene materials, and daily necessities. Information on the safety of Polylysine is introduced.
ε-Polylysine (hereinafter referred to as Polylysine) is a substance formally known as ε-Poly-L-lysine. It is a homopolymer consisting of 25 to 35 units linked by amide bonds, formed from the amino group at the ε position and the carboxyl group at the α position of the essential amino acid L-lysine. Since 1989, it has over 30 years of manufacturing experience and is widely used as a food preservative. Here, we introduce the safety of Polylysine. Polylysine has been confirmed to have high safety through acute toxicity, subacute toxicity, chronic toxicity, mutagenicity, and pharmacokinetic tests in accordance with the guidelines of the Ministry of Health, Labour and Welfare. 【Content Overview】 ■ Acute toxicity test (rats) ■ Carcinogenicity test (rats) ■ Mutagenicity test (microorganisms) ■ 3-month repeated dose toxicity test (rats) ■ Teratogenicity and reproductive test (rats) ■ Chronic toxicity/carcinogenicity combined test (rats) *For more details, please download the PDF or feel free to contact us.
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basic information
**Characteristics of Polylysine** - Exhibits excellent antibacterial effects against various microorganisms in small amounts. - Shows antibacterial effects over a wide pH range. - Has excellent thermal stability. - Demonstrates synergistic effects when used in combination with chelating agents. - Has a rich track record of use as an additive in cosmetics, hygiene materials, and daily necessities. - Possesses excellent properties as a preservative due to its high safety. - Highly soluble in water, making it easy to use in food. - Exhibits excellent growth inhibition effects against a wide range of microorganisms, including Gram-positive bacteria (such as Bacillus cereus), Gram-negative bacteria (such as Escherichia coli), and yeasts, particularly foodborne pathogens. - Also shows excellent growth inhibition effects against heat-resistant bacteria, including Bacillus subtilis. - Exhibits strong inhibitory effects against lactic acid bacteria, which significantly affect food spoilage. - High safety has been confirmed through acute toxicity, subacute toxicity, chronic toxicity, mutagenicity, and pharmacokinetic tests in accordance with the guidelines of the Ministry of Health, Labour and Welfare. *For more details, please download the PDF or feel free to contact us.*
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Line up（2）
| Model number | overview |
|---|---|
| 25% Aqueous Solution | Aqueous solution containing 25% Polylysine |
| 50% Powder | Powder consisting of 50% Polylysine and 50% dextrin |
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Our group was founded in 1906 as Sogi Electric Co., Ltd., and since then, we have been a pioneer in Japan's chemical industry, contributing to the development of society by expanding renewable energy generated by hydropower into the field of electrochemistry and developing domestic nitrogen fertilizers. Our unchanging mission is to engage in manufacturing that harmonizes with the global environment, to solve our customers' challenges in order to realize a rich life, and to cultivate outstanding human resources who can thrive globally, continuously serving society.