Scalp microbiome regulation, slowing hair loss, improving hair health and hair density, promoting Wnt/β-catenin signaling.
Alopecia is a common disorder caused by the miniaturization of hair follicles, leading to the softening of hair. The most common type of hair loss is androgenetic alopecia, which accounts for 90% of cases, with 28% of men aged 18-29 and 53% of men over 40 being affected by this condition. From a pathophysiological perspective, the causes of alopecia are multifactorial, including stress, nutrition, exposome, genetic predisposition, and hormonal sensitivity. The scalp microbiome has a significant relationship with hair growth disorders. Finding the optimal balance of both bacterial and fungal communities in hair is a step towards maintaining healthy hair. GREENTECH has developed anti-hair loss ingredients aimed at normalizing the scalp microbiome and regenerating follicular cells, focusing on the Wnt pathway, which plays a key role in the hair follicle and hair growth cycle. In Vitro 1) Inhibition of key signaling pathways for hair growth: - DDK-1 inhibition: 89% - TGFβ1 inhibition: 55% - sFRP-1 inhibition: 21% - Endothelin-1 inhibition: 21% 2) Increased proliferation of dermal papilla cells: 41% increase (better than minoxidil) 3) Adjustment of the microbiome In Vivo Hair density: 28.5% improvement
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Green Tech Co., Ltd. is a company established in 1992. The company has been importing and selling various types of plant extracts in Japan for about 20 years, and we have heard that customers in Japan perceive Green Tech as a manufacturer of plant extracts with a wide range of products. In fact, the company handles over 5,000 types of plant extracts. In addition to traditional plant extracts, we also produce and sell products that focus on the biodiversity of South America and the Amazon, including plant extracts and oils, as well as products developed based on research on microbial communities that demonstrate effectiveness in maintaining homeostasis. We also manufacture products derived from algae and microalgae, including components and extracted extracts. In recent years, we have been focusing on research and development, not only enhancing the evaluation data for our products in In-Vivo and In-Vitro studies but also conducting research and development in response to new trends such as skin microbiomes. Additionally, we are committed to developing and manufacturing products that have demonstrated effectiveness by increasing the concentration of active ingredients using our proprietary freeze technology (preservation, grinding, extraction) and fermentation technology. These manufacturing technologies are not only applied to the development of our own products but also support the development of customized products.
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Recommended usage: 1-5% - Scalp microbiome care products - Anti-hair loss products - Anti-aging hair care products - Daily hair care products
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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.