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  6. [Labor Accident Case] Organic Solvent Poisoning During Drying Operations of Pharmaceutical Intermediates

[Labor Accident Case] Organic Solvent Poisoning During Drying Operations of Pharmaceutical Intermediates

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last updated:Nov 30, 2021

理研計器 本社
理研計器 本社
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We will introduce a case where organic solvent poisoning occurred during the drying process of pharmaceutical intermediates.

This is a case study of the drying process of a pharmaceutical intermediate containing a large amount of acetone as a solvent in a pharmaceutical manufacturing facility. During the production of pharmaceuticals, workers were transferring intermediates to a drying room after filtration, moving them onto trays, and placing the trays onto the shelves of a low-temperature dryer, which resulted in exposure to high concentrations of acetone. After completing their work in the drying room, two workers reported feeling unwell and were taken to the hospital, where they were diagnosed with organic solvent poisoning and received inpatient treatment. **Suggestions** - Workers should wear personal PID monitors while working. - This will allow for monitoring exposure levels and assist in the risk assessment of chemical substances. *For more details, please refer to the PDF document or feel free to contact us.*

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[Labor Accident Case] Organic Solvent Poisoning During Drying Operations of Pharmaceutical Intermediates

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  • Related Link - https://www.rikenkeiki.co.jp/

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【Case Summary】 ■Location of Occurrence - Drying operations of a pharmaceutical intermediate containing a large amount of acetone as a solvent at a pharmaceutical manufacturing plant. ■Countermeasures - Install ventilation equipment with sufficient capacity. - Conduct measurements of the working environment. *For more details, please refer to the PDF document or feel free to contact us.

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[Labor Accident Case] Organic solvent poisoning during the drying process of pharmaceutical intermediates.

[Labor Accident Case] Organic solvent poisoning during the drying process of pharmaceutical intermediates.

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理研計器

理研計器 本社

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Riken Keiki Co., Ltd. was established as one of the companies in the "Riken Foundation" group and has since focused on the scientific and technological advancements of the Riken Institute. As a specialized manufacturer of industrial gas detection and alarm equipment, we have worked to ensure industrial disaster prevention safety by preventing explosions caused by flammable gases and monitoring harmful gases in the workplace. Moving forward, we aim for zero loss of precious human lives and valuable assets, further strengthening our technological development capabilities. We will supply high-quality industrial gas detection and alarm equipment, as well as various excellent gas sensors, to countries around the world, contributing to the assurance of industrial disaster prevention safety.

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