Introducing examples of techniques such as reaction, concentration, and crystallization! Developing methods to obtain high-quality raw materials reliably in a short time.
By utilizing chemical engineering "scale-up simulation technology" based on accumulated experience, we can proactively resolve issues that arise during scale-up and improve the robustness and productivity of manufacturing. For example, regarding the crystallization method of a raw material that is prone to oiling down and has significant variation in crystal particle size distribution, we developed a reproducible crystallization method using this technology. Additionally, for hydrated raw materials, we thoroughly examined vacuum drying conditions and developed a method to reliably obtain high-quality raw materials in a short time even at commercial scale. 【Examples of Simulation Technology (Partial)】 ■ Concentration - Simulation of solvent composition during single distillation of mixed solvents using proprietary software - Prediction of concentration time - Proposal of suitable concentration methods ■ Crystallization - Scale-up considering stirring power and changes in supersaturation over time - Development of operational methods to reproducibly obtain desired crystal forms and particle sizes - Connecting to LCM through the development of raw materials as cocrystals or suitable salts *For more details, please refer to the PDF document or feel free to contact us.
Inquire About This Product
basic information
【Other Examples of Simulation Technologies (Partial)】 ■Reaction - Heat generation characteristic acquisition using RC1 and unique simulation software incorporating the characteristics of on-site reaction kilns for heat generation control prediction. - Scale-up of gas absorption reactions. ■Filtration - Evaluation of various filtration characteristics and scale-up calculations using proprietary software (pressure filtration, centrifugal filtration, blockage filtration, aid filtration). - Simulation of cleaning and dewatering. - Proposal of suitable filtration methods. *For more details, please refer to the PDF document or feel free to contact us.
Price range
Delivery Time
Applications/Examples of results
For more details, please refer to the PDF document or feel free to contact us.
catalog（1）
Download All Catalogs
Company information
Our company is a pharmaceutical CMC research and development contract company that spun out from the CMC research division of Takeda Pharmaceutical Company Limited in July 2017. We support excellent pharmaceutical development as experts in CMC research. Our research team consists of experts with extensive experience and achievements in process chemistry, formulation research and development, and analytical testing development related to CMC research. We provide high-level services and solutions tailored to our customers' needs across each process from the early stages of pharmaceutical development to application, while flexibly collaborating. We have established a collaborative system with partner companies, enabling us to offer a one-stop service. Please utilize us as a platform for your pharmaceutical development.