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  6. Body care ingredients: Thymilin, a cellulite removal ingredient that acts on fat cells.

Body care ingredients: Thymilin, a cellulite removal ingredient that acts on fat cells.

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last updated:Feb 03, 2026

HIGUCHI INC.
HIGUCHI INC.
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Inhibition of mature adipocytes, cellulite removal, slimming, collagen production, activation of lipase, inhibition of adipocyte hypertrophy, inhibition of lipid integrity, inhibition of fat accumulation.

Timiline is a polyglucuronic acid obtained by purifying bacterial fermentation products and chemically modifying them. Greentech developed Timiline as a cellulite removal ingredient based on transcriptome analysis using DNA chips, screening 44,000 human genes and finding that Timiline promotes the expression of the FIAF adipokine gene. <Mechanism of Action> TIMILINE targets four factors to remove cellulite: - It inhibits LPL to reduce lipid biosynthesis and fat accumulation. - It stimulates ATGL to break down accumulated fat and release it extracellularly. - It promotes the transport of fatty acids from subcutaneous tissue to peripheral tissue. - It suppresses the differentiation of preadipocytes into mature adipocytes. <Efficacy> In Vitro - Suppression of intracellular lipids: -26% - Inhibition of differentiation of preadipocytes into mature adipocytes - Promotion of production: collagen +30%, integrin +17%, glycosaminoglycan +17% - Promotion of integrin production: In Vivo - Cellulite removal: improvement in 64% of subjects - Thigh circumference: approximately 67% reduction - Improvement in elasticity: 67% reported feeling it - Improvement in dimpling: 53% reported feeling it

    Cosmetic materials and raw materialsOther pharmaceutical intermediates and cosmetic ingredientsOther medical supplies and cosmetic manufacturing materials
ティミリン表紙_page-0001.jpg

Body care ingredients: Thymilin, a cellulite removal ingredient that acts on fat cells.

ティミリン表紙_page-0001.jpg
ティミリン表紙_page-0001.jpg
  • Higuchi Trading Company - Cosmetic Ingredients Product Site (Ipros)
  • Special site - Product/service details - https://pr.mono.ipros.com/higuchi-inc/product/

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Green Tech Co., Ltd. is a company established in 1992. The company has been importing and selling various types of plant extracts in Japan for about 20 years, and we have heard that Japanese customers perceive Green Tech as a manufacturer with a wide range of plant extracts. In fact, the company handles over 5,000 types of plant extracts. In addition to traditional plant extracts, it also produces and sells products focused on the biodiversity of South America, particularly Brazil, including plant extracts and oils, as well as products developed based on microbial research that demonstrate effectiveness in maintaining microbial homeostasis. The company also manufactures products derived from algae and microalgae, including components and extracted extracts. In recent years, it has been focusing on research and development, enhancing evaluation data for products in both In-Vivo and In-Vitro settings, as well as conducting research and development in response to new trends such as skin microbiomes. Additionally, it is committed to the development and manufacturing of products that have demonstrated effectiveness by increasing the concentration of active ingredients using its proprietary freeze technology (preservation, grinding, extraction) and fermentation technology. These manufacturing technologies are not only used for the development of its own products but also support the development of customized products.

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Properties: Powder (water-soluble) Recommended addition amount: 0.5 to 3.0% Products for slimming, cellulite removal, and unevenness improvement Beauty body care products Body care products for improving firmness

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Body care ingredients that work on fat cells for slimming and cellulite removal: Thymilin.

Body care ingredients that work on fat cells for slimming and cellulite removal: Thymilin.

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Body care ingredients: African traditional breast enhancement plant extract Kigerin (the best-selling product in France among GT products).

Body care ingredients: African traditional breast enhancement plant extract Kigerin (the best-selling product in France among GT products).

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Body care ingredient, deodorizing component that balances the bacterial flora, lactoferrin.

Body care ingredient, deodorizing component that balances the bacterial flora, lactoferrin.

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Cosmetic ingredients: Introducing over 100 active components produced in 17 regions of France.

Cosmetic ingredients: Introducing over 100 active components produced in 17 regions of France.

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Company information

HIGUCHI

HIGUCHI INC.

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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.

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