Introducing cells alive into the interior of porous materials!
This is a method to solve the issue of "incomplete infiltration" in tissue regeneration materials. Using vacuum-pressure infiltration, we were able to introduce cells deep into porous materials (e.g., collagen, PLA, etc.). Subsequent proliferation and differentiation have also been confirmed.
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basic information
Patent application filed [Application No. 2020-094285]
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Applications/Examples of results
Regenerative materials for organizations, three-dimensional culture research materials, etc.
Detailed information
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For the regeneration of three-dimensional tissues in the human body, such as cartilage and bone, "porous materials" are used as scaffold materials to promote greater cell infiltration. However, it has been pointed out that in practice, cells do not infiltrate, leading to a problem known as "infiltration deficiency." (Left figure) This issue has been completely resolved by the vacuum pressure impregnation method. (Right figure)
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