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  6. Seamless capsule

Seamless capsule

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OptiGel Micro

last updated:Sep 04, 2023

キャタレント・ジャパン 東京本社
キャタレント・ジャパン 東京本社
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A new drug delivery system (DDS) technology that makes it smaller and easier to drink, while also allowing for an increase or adjustment of the active ingredient content.

As an innovator in soft capsule technology, we have pursued various formulations to enhance product value over many years, resulting in the birth of OptiGel Micro (seamless capsule). This is truly the crystallization of drug delivery system (DDS) technology that clears the challenges of formulation development, such as complex formulations, the formulation of poorly soluble compounds, and the pursuit of better bioavailability. OptiGel Micro (seamless capsule) forms spherical capsules using a manufacturing process that utilizes droplets from the laminar flow of coating liquid and fill liquid, unlike the rotary die method used for soft capsule formation. The capsule size ranges from 1 to 7 mm, allowing for the production of smaller capsules than traditional soft capsules. The excipients are made from the same materials as other gelatin capsule coatings and can accommodate a wide range of contents, just like other products.

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Seamless capsule

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  • Related Link - https://japan.catalent.com/oral-dose/softgel/optig…

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basic information

Utilizing size, we can effectively deliver active ingredients to all patients: ■ Ideal for patients who may have difficulty swallowing, such as children, the elderly, and cancer patients. The seamless capsule technology supports adherence to dosage and improves compliance. ■ When a gradual increase in dosage is required for treatment, appropriate amounts of capsules can be packaged in sachets. Each capsule contains the same amount of active ingredient, allowing for a gradual increase in dosage through the number of capsules, enabling multiple packaging specifications from the same manufacturing lot. ■ Over 10 years since commercial production began. More than 6 billion capsules are produced annually, demonstrating a proven track record of drug delivery system (DDS) technology. ■ Excellent content uniformity of the compound minimizes variability in intake among patients. ■ Contributes to a faster onset of pharmacological action, reduction of API dosage, and overall improvement in therapeutic performance.

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Applications/Examples of results

■Ease of swallowing ■Ideal for indications that require adjustment of drug content ■Coating similar to other gelatin capsules, accommodating a wide range of contents ■Available in various sizes and colors, contributing to differentiation and branding

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キャタレント・ジャパン

キャタレント・ジャパン 東京本社

Manufacturing and processing contract

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Our company is a global enterprise that provides advanced and excellent development and manufacturing technologies in the fields of oral pharmaceuticals, biopharmaceuticals, and consumer health. As an innovator in formulation development and manufacturing, we propose better treatment and health-appropriate solutions, and we support the stable delivery of high-quality products that are highly reliable.

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