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  6. Oral fast-dissolving tablet

Oral fast-dissolving tablet

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Zaidis

last updated:Sep 04, 2023

キャタレント・ジャパン 東京本社
キャタレント・ジャパン 東京本社
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Zydis is a unique orally disintegrating tablet from Catalent that dissolves instantly in the mouth and can be taken without water.

The speed at which it dissolves in just 3 seconds is up to 10 times faster compared to typical orally disintegrating tablets. This is top-class technology in over-the-counter pharmaceuticals. The easy-to-take and swallowable dosage form is ideal for patients with swallowing difficulties, as well as for children and the elderly. Additionally, it serves as an ideal platform for active ingredients that need to be rapidly absorbed after administration, such as pain relievers, allergy medications, and motion sickness preventatives. Currently, Zydus's technology is utilized in over 20 products across 60 countries. In the process, we have pursued new dosage forms that are easier to take, contributing to the expansion of our customers' product portfolios. The improved pharmacokinetics before gastrointestinal absorption, the ease of use that aids patient adherence to dosage, and the dosage form that makes it easy to highlight product features. Catalent is an innovative partner that enhances the cost-effectiveness of development investments and contributes to our customers' branding.

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Oral fast-dissolving tablet

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  • Related Link - https://japan.catalent.com/oral-dose/zydis-odt-tec…

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basic information

Zydis's technical team provides data packages that support regulatory submissions by evaluating active ingredients and characteristics during formulation throughout the entire development process using analysis and data interpretation: ■ Feasibility studies ■ Analytical and regulatory services ■ Consistent lifecycle management from drug discovery to market launch ■ Handling of highly pharmacologically active drugs and regulated pharmaceuticals by experts ■ Non-clinical, pilot, and large-scale production compliant with cGMP in Europe and the United States

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Applications/Examples of results

■Ease of ingestion: Dissolves in just 3 seconds, has a pleasant mouthfeel, and can be taken anywhere without water. ■Taste and flavor: Essential taste-masking technology and a variety of flavors for specific markets such as pediatric and veterinary medicines. ■Improved absorption rates for all active ingredients. ■Unique packaging: Child-resistant packaging, among others. ■Flexibility: A wide range of target users and diseases. ■For specific patients: - Those with swallowing difficulties. - Children and the elderly who require ease of ingestion. - Those who need rapid onset of effects. ■Wide range of disease areas: - Allergy medications (antihistamines, immunotherapy, etc.) - Antiemetics (motion sickness) - Gastrointestinal medications (diarrhea, constipation, etc.) - Antipsychotics (schizophrenia, etc.) - Anxiolytics (antidepressants)

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キャタレント・ジャパン

キャタレント・ジャパン 東京本社

Manufacturing and processing contract

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Our company is a global enterprise that provides advanced and excellent development and manufacturing technologies in the fields of oral pharmaceuticals, biopharmaceuticals, and consumer health. As an innovator in formulation development and manufacturing, we propose better treatment and health-appropriate solutions, and we support the stable delivery of high-quality products that are highly reliable.

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