We will introduce a case study of TRPV1 / TRPM8 measurement using Port-a-Patch.
Application Note: TRPV1 and TRPM8 recorded on Nanion's Port-a-Patch *For more details, please refer to the PDF document or feel free to contact us.
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basic information
A patch clamp system of the world's smallest class that allows for immediate data acquisition and verification at your fingertips, easily operable by anyone. This system is optimal for safety testing, toxicity testing, pharmacological testing, and screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes, capable of performing giga-seal recordings. 【Features】 - No need for manual patch clamp experience or difficult operations - No need for microscope, vibration table, manipulator, Faraday cage, or puller - 20 to 50 data points per day - Automation from giga-seal formation to whole-cell formation - Compatible with voltage-dependent, ligand-dependent, and temperature-dependent channels - Measurement of action potentials via current clamp is also possible - Supports a wide range of applications, enabling rapid assay system development - Borosilicate glass chips reduce compound adsorption - Optional temperature control (10 to 50°C), capable of extracellular/intracellular perfusion - Can be integrated with amplifiers such as HEKA and Axon that you already have.
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Delivery Time
※Delivery times may vary depending on stock availability, so please feel free to contact us.
Applications/Examples of results
For more details, please refer to the PDF document or feel free to contact us. For inquiries about products, requests for demos, requests for catalogs, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp
catalog（11）
Download All Catalogs![[Measurement Example] TRPV1 / TRPM8 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/eb3/724355/IPROS42625688419790382378.jpeg?w=120&h=170)
![[Measurement Example] GABAA | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/69d/743592/IPROS93255623448414496753.jpeg?w=120&h=170)
![[Measurement Example] Cardiomyocytes | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/e2a/779271/IPROS05954020397590055143.jpeg?w=120&h=170)
![[Measurement Example] NaV1.7 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/2a2/779272/IPROS75094622369255668323.jpeg?w=120&h=170)
![[Measurement Example] TRPV4 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/de7/724357/IPROS41434771184729375985.jpeg?w=120&h=170)
![[Measurement Example] hERG / Nav1.5 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/820/745363/IPROS34967891323291495648.jpeg?w=120&h=170)
![[Measurement Example] TRPA1 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/059/724273/IPROS77818150870468009918.jpeg?w=120&h=170)
![[Measurement Example] TRPM8 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/d2a/724352/IPROS06990709343623289639.jpeg?w=120&h=170)
Company information
Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp