Solution for real-time monitoring and controlling of occlusion
Hemolysis is one of the major blood trauma in extracorporeal circulation. The occlusion is a parameter to eliminate deteriorative blood trauma as well as to improve assisted circulation efficacy during cardiopulmonary bypass (CPB). The strength of occlusion is adjusted manually in common method currently used, so the variation or deterioration of roller pumps or tubes causes hemolysis or multiple organ failure. The present invention relates to a new occlusion simulation model for evaluating the occlusion by the thickness of the flow in the tubing compressed with the CPB roller and raceway. The red-colored densitometry images were used to calculate the thickness of occluded flow channel.
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The revenue generated from technology transfer is reinvested as new research funding for universities and researchers, and is utilized to create further research outcomes. To ensure the smooth operation of this cycle, known as the "Intellectual Creation Cycle," we will vigorously promote technology transfer. The types of seeds we handle include patents, know-how, databases, and programs. We have established a collaborative framework by signing basic technology transfer agreements with the following universities (as of June 1, 2025): Tohoku University, Hirosaki University, Iwate University, Akita University, Fukushima University, Yamagata University, Tohoku Gakuin University, Iwate Medical University, Fukushima Medical University, Aizu University, Miyagi University, Hokkaido University, Muroran Institute of Technology, and Showa Medical University.
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