We will introduce a case study of GABAA measurement using Port-a-Patch.
Application Note: Activation and inhibition of GABAA a5b3g2 receptors on the Port-a-Patch *For more details, please refer to the PDF document or feel free to contact us.
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basic information
A patch clamp system of the world's smallest class that allows for immediate data acquisition and verification at your fingertips, easily operable by anyone. This system is optimal for safety testing, toxicity testing, pharmacological testing, and screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes. It can perform giga-seal recordings. 【Features】 - No need for manual patch clamp experience or complicated operations - No need for microscope, vibration table, manipulator, Faraday cage, or puller - 20 to 50 data points per day - Automation from giga-seal formation to whole-cell formation - Compatible with voltage-dependent, ligand-dependent, and temperature-dependent channels - Capable of measuring action potentials using current clamp - Supports a wide range of applications, enabling rapid assay system development - Reduces compound adsorption with borosilicate glass chips - Optional temperature control (10 to 50°C), capable of extracellular/intracellular perfusion - Can be integrated with amplifiers such as HEKA and Axon that you already have.
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Delivery Time
※Delivery times may vary depending on stock availability, so please feel free to contact us.
Applications/Examples of results
For more details, please refer to the PDF document or feel free to contact us. For inquiries about products, requests for demos, requests for catalogs, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp
catalog（11）
Download All Catalogs![[Measurement Example] GABAA | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/69d/743592/IPROS93255623448414496753.jpeg?w=120&h=170)
![[Measurement Example] Cardiomyocytes | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/e2a/779271/IPROS05954020397590055143.jpeg?w=120&h=170)
![[Measurement Example] NaV1.7 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/2a2/779272/IPROS75094622369255668323.jpeg?w=120&h=170)
![[Measurement Example] hERG / Nav1.5 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/820/745363/IPROS34967891323291495648.jpeg?w=120&h=170)
![[Measurement Example] TRPA1 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/059/724273/IPROS77818150870468009918.jpeg?w=120&h=170)
![[Measurement Example] TRPM8 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/d2a/724352/IPROS06990709343623289639.jpeg?w=120&h=170)
![[Measurement Example] TRPV1 / TRPM8 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/eb3/724355/IPROS42625688419790382378.jpeg?w=120&h=170)
![[Measurement Example] TRPV4 | Port-a-Patch](https://image.mono.ipros.com/public/catalog/image/01/de7/724357/IPROS41434771184729375985.jpeg?w=120&h=170)
Company information
Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp