Silica-based medium-polarity filler with carboxypropyl groups.
Bond Elut CBA is a silica-based medium-polarity packing material with carboxypropyl groups, which exhibits hydrophilic/hydrophobic interactions depending on the matrix and solvent environment. Its main characteristic lies in weak cation exchange. Due to its pKa value of 4.8, CBA does not require the extremely high alkaline environment that other cation exchange packing materials need for elution. At pH 4.8 and above, most of the functional groups carry a negative charge as cation exchange sites. Lowering the pH to 2.8 neutralizes CBA, allowing it to release and elute the compounds it has retained from the packing material. CBA is particularly suitable when dealing with very strong cationic compounds. Additionally, CBA broadens the selectivity range for counterions compared to other cation exchangers, increasing the options for elution buffers. *For more details, please refer to the PDF document or feel free to contact us.*
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**Features** - Irregular acid-purified silica of 40μm or 120μm - Average pore size: 60Å - Functional groups: Carboxylic acid - End-capping: Yes - Carbon loading rate: 7% - Packing material pKa: 4.8 - Ion exchange capacity: 0.35 meq/g - Retention mechanism: Weak cation exchange - Packing amounts: 50mg, 100mg, 200mg, 500mg, 1g, 2g - Column sizes: 1mL, 3mL, 6mL, 10mL, 12mL - Column shapes: Straight, LRC *For more details, please refer to the PDF document or feel free to contact us.*
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For more details, please refer to the PDF document or feel free to contact us.
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