Filling: PUPSIT-compatible vial filling assembly line

We are pleased to announce that we will be exhibiting at BioJapan 2024. At our booth, we will showcase products across the three processes of 'Testing', 'Culturing', and 'Formulation'. In the 'Testing Process', we will introduce "alternative methods to animal testing" such as organ-on-a-chip and monocyte activation tests. In the 'Culturing Process', we will propose various assembly products and depth filters for building manufacturing lines. In the 'Formulation Process', we will present products related to the washing and storage solutions for cell therapies, as well as filling and logistics for final products. We understand that you will be busy during this period, but we sincerely look forward to welcoming many of you, so please feel free to invite others. ◆ Testing Process – Alternative Methods to Animal Testing – - Drug screening & toxicity testing with organ-on-a-chip - Pyrogen testing with MAT kits ◆ Culturing Process – Consumables – - Cell lysis enzyme endonuclease - Cryopreservation bags - Cell culture bags - Media bags - Intermediate product transfer & storage bags - Culturing depth filters ◆ Pharmaceutical Process – Filling & Logistics – - Cell product filling machines - Non-freezing cell storage solutions - Regenerative medicine product logistics boxes & loggers

We exhibited at the "9th Bio Pharmaceutical EXPO" held at Tokyo Big Sight from July 9 to 11, 2025! Thank you very much to everyone who visited us. Main Exhibited Products 【Solid Dosage Form Related Products】 Mixer, Torque, Rheometer Tabletop Tablet and Granule Coating Equipment Powder Sampler IVIVC Dissolution Tester BIO-DIS III Functional additives for improving the solubility of poorly soluble drugs Pharmaceutical cleaning agents compatible with cleaning validation Granulated lactose developed for direct compression, spray-dried lactose Tablet press mortar and pestle, reducing compression time by up to 50% Functional ready-to-fill capsules galenIQ Isomalt Hydrate, and others 【Bio Pharmaceutical Related Products】 Single-use Depth Filter Single-use Mixer Bag System Single-use Assembly Bag Culture Bag SafeCell Pyrogen Test Kit (MAT Test Method) instaCELL High-precision Incubator AVATAR ODYSSEY Biomimetic System Organ-on-a-Chip, and others

Thank you very much for visiting our booth at the "24th Annual Meeting of the Japanese Society for Regenerative Medicine" held at Pacifico Yokohama from March 20 to 22, 2025, during the latest technology introduction corner. Thanks to your support, we were able to conclude the event successfully. If you have any questions regarding the products you viewed, please feel free to reach out to us. We will respond to inquiries received during the event in due course. We appreciate your continued support of Higuchi Shokai. Exhibited Products: - Non-freezing cell preservation solution (Cellgentec) - Single-use bags, sterilized capsule filters (Advanced Microdevices) - Assembly tubes, bottles (WHK BioSystems) - Bags for cell freezing preservation and culture (TECHNO FLEX) - Culture devices (xcellbio)