Achieving a high survival rate and recovery rate.
- In the cell centrifugation process, shear forces are kept low, allowing for a seamless transition from process development (0.1 L) to GMP-compliant manufacturing (20 L). - In the closed system cell recovery process, cell processing time is reduced by 50%. - Cell recovery rate improved to over 90%. - Robust results achieved even at a cell density of up to 108 cells/mL. - Improved cell viability due to low shear counterflow separation.
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basic information
Conventional centrifugation methods generate high shear forces, which often damage cells during cell processing in advanced therapies. Ksep50 employs high-performance counter-flow centrifugation, reducing shear forces to minimize cell lysis and achieve high survival and recovery rates. By utilizing this automated single-use system, manual operations are reduced, enabling a seamless scale-up from process development to commercial production while maintaining high cell survival rates and quality, all while keeping the risk of contamination low.
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Company information
Sartorius Stedim, established in 2007 through the merger of the German company Sartorius, founded in 1870, and the French company Stedim, is a pioneer in "Single-Use Technology (SUT)." As a company capable of providing comprehensive technical support to the pharmaceutical and biotechnology industries, its cutting-edge technology is highly regarded worldwide in the fields of scientific instruments and biotechnology.