We will introduce a measurement example of TMEM175 using SURFE²R 96SE.
Measurement Example: Investigating TMEM175 with the SURFE2R 96SE *For more details, please refer to the PDF document or feel free to contact us.
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basic information
Currently, the mainstream method for evaluating transporter activity is the uptake assay using RI-labeled substrates. However, there are several issues, such as the need for specialized experimental facilities, the requirement for complex waste disposal, the fact that the desired substrate is not always commercially available as RI-labeled, and that the endpoint is measured after uptake. The SURFE²R (Surface Electrogenic Event Reader) technology does not require RI labeling, specialized experimental facilities, or waste disposal, and it enables real-time evaluation of the activity of transporters (symporters, exchangers, unipoters) and pumps. - Direct measurement of transporter currents using Solid Supported Membrane (SSM) - Experiments can be conducted with membrane fragments prepared from biological membranes or proteoliposomes reconstituted with the target membrane protein - Light stimulation is possible (optional) - An all-in-one device that integrates a dispenser, measurement section, and computer - 150 data points per day
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※The delivery time may vary depending on the stock status, so please feel free to contact us.
Applications/Examples of results
For more details, please refer to the PDF document or feel free to contact us. For inquiries about products, requests for demos, requests for catalogs, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp
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Company information
Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp