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  4. Optical Analysis Equipment
  5. Raman Spectrophotometer
  6. Timegate Raman Spectrometer PicoramanM3

Timegate Raman Spectrometer PicoramanM3

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Timegate

last updated:Aug 06, 2025

HORIZO(ホライゾ)
HORIZO(ホライゾ)
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Faster than fluorescence. Timegate Raman spectroscopy.

Fluorescence has become a major challenge in Raman spectroscopy. Timegate Instruments' patented Timegated Raman technology was developed to address this challenge. The phenomena of Raman scattering and fluorescence occur on different time scales. Raman scattering occurs on a very short sub-picosecond (less than one trillionth of a second) time scale, while the decay time of fluorescence is characterized by being very long. By using time-gate technology, it not only distinguishes between fluorescence and Raman signals but also provides temporal information about the Raman signals. Additionally, delayed noise components such as thermal radiation are ignored in Timegate Raman, which means they do not affect measurements. This allows for the analysis of structural changes in materials that undergo polymorphism at high temperatures (500-900°C), such as spodumene, while suppressing the effects of fluorescence. Timegate Raman spectroscopy, equipped with a real fluorescence removal function, makes the development of biopharmaceutical processes faster and more reliable. We deliver data and results that were previously unattainable into your hands. Reference: https://youtu.be/bsi29R-K4bo

    Culture vesselRaman SpectrophotometerReaction Crystallizer
RGB

Timegate Raman Spectrometer PicoramanM3

RGB TG Picoraman M3 with ProbeproMini.jpg
RGB TG Picoraman M3 with ProbeproMini.jpg
  • Related Link - https://horizo.co.jp/catalogue_materials

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basic information

One of the features of the Timegate Raman spectrometer is that it is an advanced spectroscopic analysis device equipped with a unique "CMOS-SPAD sensor" developed by Timegate. This sensor can detect single photons with high precision. Furthermore, by using Timegate technology, it is possible to selectively detect photons within a specific time window (100 picoseconds), significantly suppressing the effects of fluorescence emission. This allows for the capture of Raman signals with very high accuracy. The Timegate Raman spectrometer demonstrates exceptional performance, especially in the analysis of weak signals, achieving precision and sensitivity that conventional spectrometers cannot provide. With this time-gated technology, high-speed and high-precision measurements enable true real-time monitoring and control of bioprocesses. The PicoRaman M3 is the first spectrometer in the biopharmaceutical market to feature real fluorescence suppression capabilities. Its non-destructive, non-contact, label-free, and user-friendly measurement technology ensures safe monitoring. *For more details, please feel free to contact us.*

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Applications/Examples of results

Biopharmaceuticals, CDMO, lithium-ion battery development research Bioprocess control, real-time reaction monitoring, exosome research, polymorphism research, etc. ■ For more details, please visit the link below. https://www.horizo.co.jp/ ■ You can also make a reservation for a demo through the website. Feel free to contact us with any inquiries. contact@sub.horizo.co.jp

Line up(3)

Model number overview
PicoRaman M3 Spectrometer Simplifies complex processes in the biomanufacturing field. The PicoRaman M3 spectrometer serves as a monitoring tool to optimize bioprocesses step by step, achieving high productivity and profitability in processing.
ProbePro Mini ProbePro Mini provides a solution for easily and continuously measuring critical process parameters through an optical interface. Specifically developed for liquid biopharmaceutical applications.
SampleCube SampleCube enables analysis over a wide sample surface. A larger surface area allows for more representative sampling. The sample cup holder has an option for eccentric rotation, and the measurement probe can be moved in a scanning motion.

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Transformation of biopharmaceutical manufacturing through real-time in-situ monitoring.

Transformation of biopharmaceutical manufacturing through real-time in-situ monitoring.

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Comprehensive Catalog 2025 04

Comprehensive Catalog 2025 04

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Timegate Raman Spectroscopy Rental Program

Timegate Raman Spectroscopy Rental Program

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Timegate Raman Spectroscopy Rental Program Launch

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The elimination of the effects of fluorescence, which has been difficult with conventional Raman spectroscopy, is achieved through Timegate's unique picosecond time-resolved technology. Analysis of biological samples and materials with strong fluorescent backgrounds will be possible with unprecedented clarity. Timegate's Timegated Raman technology solves the challenges of traditional Raman spectroscopy. Rental of Timegate Raman spectrometers has begun! We support non-destructive and high-speed analysis of biological materials, battery materials, polymers, and pharmaceuticals. We are accepting rentals of Timegate Raman spectrometers and are also looking for agents.

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Notice of Participation in the 40th Annual Meeting of the Japanese Society of Pharmaceutical Sciences: May 22 (Thursday) to 24 (Saturday), 2025. Equipment exhibition will be on the 23rd and 24th.

  • Seminar・Event

We will exhibit at the 40th Annual Meeting of the Japanese Pharmaceutical Society. ■ Timegate Corporation Raman Spectroscopy Device (Live Demonstration) A real-time Timegate Raman spectroscopy system that suppresses the effects of fluorescence. It instantly detects changes in crystal growth, polymorphism, and drying processes during the crystallization process, contributing to the optimization of formulation quality. Additionally, it minimizes variability in the manufacturing process of biopharmaceuticals, achieving stable quality control and process optimization. 【Other Products】 ■ Cellexus Corporation Airlift Bioreactor (Panel and Catalog Display) Real-time monitoring of biopharmaceutical production processes is possible through collaboration with Timegate Raman. ■ RheaVita Corporation Spin Freeze-Drying System (Panel and Catalog Display) A groundbreaking spin freeze-drying technology that enables rapid freeze-drying of biopharmaceuticals. ■ Magritek Corporation Desktop NMR System (Panel and Catalog Display) 【Venue Information】 TFT Building, West Wing, 2nd Floor, 3-4-10 Ariake, Koto-ku, Tokyo May 22 (Thursday) to 24 (Saturday), 2025 *Exhibition will be on the 23rd and 24th.

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HORIZO(ホライゾ)

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HORIZO Corporation leverages connections with various regions and people around the world to assist researchers and companies passionate about the advancement of science in solving and streamlining research challenges through new technologies. In promoting our business, we strive to provide technologies and products in the scientific field that are not bound by conventional practices, continuing to take on new challenges and working together with everyone to create a better future. In the scientific market, new products and technological services that no one has dared to challenge are often pursued by small businesses, but we will boldly take on those untapped areas as pioneers without hesitation.

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The related categories of Culture vessel

  • Pharmaceutical and food related
  • Optical Analysis Equipment
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  • Reaction Crystallizer
          

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