We will introduce a case study of measuring cardiomyocytes using Port-a-Patch.
Application Note: Recordings of Action Potentials in Mouse ES Cell-Derived Cor.At Cardiomyocytes on Nanion's Port-a-Patch *For more details, please refer to the PDF document or feel free to contact us.*
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basic information
A world-class, ultra-compact patch clamp system that allows anyone to easily operate and quickly obtain and verify data at hand. This ultra-compact patch clamp system is ideal for safety testing, toxicity testing, pharmacological testing, and screening of compounds at the cellular level in the functional structural analysis of ion channels, research on related diseases, and drug development processes, capable of performing giga-seal recordings. 【Features】 ■ No need for manual patch clamp experience or complicated operations ■ No need for microscope, vibration isolation table, manipulator, Faraday cage, or puller ■ 20 to 50 data points per day ■ Automation of giga-seal formation and whole-cell formation ■ Compatible with voltage-dependent, ligand-dependent, and temperature-dependent channels ■ Measurement of action potentials using current clamp is also possible ■ Supports a wide range of applications and enables rapid assay system development ■ Reduces compound adsorption with borosilicate glass chips ■ Optional temperature control (10 to 50°C), capable of extracellular/intracellular perfusion ■ Can be integrated with amplifiers such as HEKA and Axon that you already have.
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Applications/Examples of results
For more details, please refer to the PDF document or feel free to contact us. For inquiries about products, requests for demos, requests for catalogs, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp
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Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp