Fast! Clean! And complete! MS-grade trypsin to solve the challenges of protein digestion.
With RapiZyme trypsin, it is possible to achieve uncompromising speed and clean digestion due to extremely high self-digestion resistance, high purity, and improved activity. It solves issues such as long pre-treatment times, noise from impurities (self-digestion, incompatibility, non-specific cleavage, cleavage errors), and poor reproducibility, resulting in highly reproducible and efficient digestion with minimal artifacts and high coverage. 【Features】 - High self-digestion resistance allows for the use of a high ratio (1:5) of enzyme, enabling efficient digestion in a short time. - Clean baseline without peaks of noise or artifacts. - High sequencing coverage rate. - Achieves reproducibility and predictability with chemically optimized recombinant expressed porcine trypsin. - Improved stability, recovery rate from vials, and activity upon re-dissolution. - Excellent robustness and flexibility to accommodate various protocols.
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basic information
RapiZyme Trypsin is a uniformly methylated recombinant (non-animal derived) trypsin that does not contain chymotrypsin. Furthermore, it is freeze-dried with LC-MS compatible excipients, making re-dissolution easy and predictable, and improving recovery rates from vials.
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Applications/Examples of results
This is an MS-grade protein digestion enzyme that can be used for characteristic analysis such as peptide mapping of biopharmaceuticals, identification and monitoring of HCPs, and bottom-up proteomics. For customers conducting peptide mapping, we also offer the [PeptideWorks Trypsin Protein Digestion Kit], which includes RapiZyme Trypsin and other necessary items for purification in a kit format.
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Company information
Waters Corporation, headquartered in Milford, Massachusetts, USA, has played a pioneering role as a specialized manufacturer of liquid chromatography since its establishment in 1958. Actively engaged in the development of new products and technologies, it has grown into an international group company that supplies not only high-performance liquid chromatography but also mass spectrometers (MS) and thermal analysis instruments. Waters Japan started operations in 1973 (Showa 48) as the Japanese base of Waters Corporation. Inheriting the corporate ethos of the U.S. headquarters, we have made "Customer Success" our mission and continue to provide innovative technologies and lab solutions.
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