Cosmetic ingredient Elastin for elasticity improvement with reconstructed pentapeptide Elacelf.
A pentapeptide synthesized by mimicking the fragment of MFAP4. It recognizes damage, stimulates the production of MFAP4, and reconstructs elastin.
Elaself is a pentapeptide (valine-serine-glycine-isoleucine-arginine) synthesized to mimic a fragment of MFAP4. MFAP4 is necessary for binding fibrillin chains to form microfibrils. These microfibrils are then further modified to become mature elastic fibers (elastin). <In Vitro> MFAP4 gene expression (+30%) Collagen type I gene expression (+30%) Increased intracellular collagen levels in NHDF cells (20-60%) Increased elastin levels <In Vivo> Improvement in skin elasticity (R2: 20%, R5: 25%) Reduction in wrinkle depth (-40%)
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basic information
Contipro is a biotechnology company and a global manufacturer of active ingredients used in the pharmaceutical and cosmetics industries for nearly 30 years. We offer a range of products including sodium hyaluronate and its derivatives produced by fermentation, as well as distinctive peptides and natural polysaccharides.
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Recommended blending amount: 0.01 – 1% It is recommended to add during the cold process.
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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.