How do ion channels explain pain?

A central role in both the physiological pain response and the pathophysiological changes underlying chronic pain.

One in three adults experiences chronic pain in their lives, and the effectiveness of treatments is limited, leading to a worsening opioid crisis. Understanding the balance between pain and chronic pain, as well as methods for pain treatment, is becoming increasingly important. Ion channels play a central role in both the physiological pain response and the pathophysiological changes underlying chronic pain. These specialized protein structures embedded in the cell membrane control the flow of ions such as sodium (Na+), potassium (K+), and calcium (Ca2+) across the cell membrane. The movement of these ions generates electrical signals that propagate along neurons and ultimately reach the brain, where they are recognized as pain. *For more detailed information, please refer to the related links. Feel free to contact us for further inquiries.*

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