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  6. [Case Study] Efficient Analysis of Sunscreen Ingredients Using UHPLC System

[Case Study] Efficient Analysis of Sunscreen Ingredients Using UHPLC System

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last updated:Nov 19, 2025

サーモフィッシャーサイエンティフィック株式会社/Thermo Fisher Scientific K.K.
サーモフィッシャーサイエンティフィック株式会社/Thermo Fisher Scientific K.K.
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Rapid and accurate analysis of multiple ultraviolet filter components using a high-precision, environmentally friendly UHPLC method!

This technical document introduces a method for efficiently analyzing ten types of ultraviolet filter components contained in five types of sunscreen using a UHPLC system under a single analytical condition. The results of the validation of the method's accuracy and precision showed that the peak area RSD was below 1.10%, and the retention time RSD was below 0.50%, indicating high precision. Additionally, by transitioning the existing analytical method to the UHPLC method, we reduced solvent consumption and waste generation, and replaced tetrahydrofuran (THF) used in the sample solution with a more environmentally friendly solvent, thereby reducing the environmental impact. 【Features】 ■ Efficient analysis of ten types of ultraviolet filter components under a single analytical condition ■ High precision with peak area RSD below 1.10% and retention time RSD below 0.50% ■ Reduction of solvent consumption and waste generation through the UHPLC method ■ Thorough evaluation of accuracy, linearity, and precision ■ Use of environmentally friendly solvents to reduce environmental impact *For more details, please download the PDF or feel free to contact us.

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[Case Study] Efficient Analysis of Sunscreen Ingredients Using UHPLC System

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  • For more details about the Thermo Scientific Vanquish HPLC/UHPLC system, click here.
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【System Configuration】Thermo Scientific Vanquish Flex UHPLC System Pump: Thermo Scientific Vanquish Binary Pump F Autosampler: Thermo Scientific Vanquish Split Sampler FT Column Compartment: Thermo Scientific Vanquish Column Compartment H Detector: Thermo Scientific Vanquish Diode Array Detector FG Software: Thermo Scientific Chromeleon Chromatography Data System 7.3.1 Column: Thermo Scientific Accucore C18 Column 2.6 μm, 2.1 x 100 mm

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For more details, please download the PDF or feel free to contact us. It can only be used for research purposes and cannot be used for diagnostic purposes.

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UHPLC-DAD sunscreen analysis using simultaneous measurement of multiple sunscreen ingredients with the Vanquish Flex UHPLC system.

UHPLC-DAD sunscreen analysis using simultaneous measurement of multiple sunscreen ingredients with the Vanquish Flex UHPLC system.

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Vanquish Flex UHPLC System

Vanquish Flex UHPLC System

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サーモフィッシャーサイエンティフィック株式会社/Thermo

サーモフィッシャーサイエンティフィック株式会社/Thermo Fisher Scientific K.K.

Testing, Analysis and Measurement

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Thermo Fisher Scientific K.K., the Japanese subsidiary of Thermo Fisher Scientific Incorporated, is a sales company for comprehensive system analysis instruments, bio-related equipment, and research reagents. In Japan, it has bases in Yokohama, Tokyo, Osaka, Fukuoka, and Nagoya, handling various analytical instruments including mass spectrometers, various bio-related equipment, measuring instruments, medical devices, lab software, and research reagents.

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